Complex Regional Pain Syndrome Clinical Trials
Here are the 6 most popular medical studies for complex regional pain syndrome
Non-invasive Brain Stimulation
TMS for Complex Regional Pain Syndrome
This trial is testing whether TMS can help with the Complex Regional Pain Syndrome (CRPS). It is hypothesized that those who receive TMS will have less pain and other symptoms than those who don't.
Opioid Antagonist
LDN for Complex Regional Pain Syndrome
This trial is testing whether low-dose naltrexone can help relieve symptoms of complex regional pain syndrome. Participants will be given either LDN or a placebo for a few weeks, and will be asked to come in for several visits, which will include tests, physical assessments, and questionnaires.
Cannabinoid
BRC-002 for Complex Regional Pain Syndrome
This trial aims to study how cannabinoids can help relieve pain in complex regional pain syndrome (CRPS). They will use various tests to see how cannabinoids affect pain and inflammation in patients with CRPS. The
Behavioural Intervention
rTMS + Rehabilitation for Complex Regional Pain Syndrome
This trial will test if rTMS and rehab can reduce pain from CRPS Type 1. Subjects get 4 rTMS treatments and 2 rehab treatments in 1st wk, then 2 rTMS and 2 rehab treatments in following wks. Outcome measured by pain ratings, PROMIS, GROC, grip strength/leg press.
Popular filter options for complex regional pain syndrome trials
CRPS Clinical Trials
View 18 CRPS medical studies.
Procedure
Nerve Block + Physiotherapy for Complex Regional Pain Syndrome
This trial will assess a novel treatment protocol for Complex Regional Pain Syndrome (CRPS), a debilitating condition affecting 1 of 5 Canadians, to determine its efficacy and reduce healthcare cost.
Chronic Pain Clinical Trials
View 7 Chronic Pain medical studies.
Opiate Antagonist
Low dose naltrexone for Complex Regional Pain Syndrome
This trial aims to study the effects of low dose naltrexone on patients with Complex Regional Pain Syndrome (CRPS). Patients will be randomly assigned to receive either low dose naltrexone or
Behavioural Intervention
Virtual Reality Therapy for Complex Regional Pain Syndrome
This trial tests if VR can help reduce chronic pain due to CRPS. It's noninvasive and cost-effective, with potential to help people with this condition. #virtualreality #CRPS #chronicpain
Behavioral Intervention
Resilience Coaching for Adolescent Chronic Pain
This trial will research how resilience coaching could help teens with chronic pain. It'll compare those who receive resilience coaching to those who receive usual care. Results will show if it helps with functional disability, psychological distress, and pain intensity.
Complex Regional Pain Syndrome Clinical Trials With No Placebo
View 19 complex regional pain syndrome medical studies that do not have a placebo group.
Procedure
Nerve Block + Physiotherapy for Complex Regional Pain Syndrome
This trial will assess a novel treatment protocol for Complex Regional Pain Syndrome (CRPS), a debilitating condition affecting 1 of 5 Canadians, to determine its efficacy and reduce healthcare cost.
Neurotoxin
Botulinum Toxin Injection for Complex Regional Pain Syndrome
Objective: The primary aim is to evaluate the efficacy of botulinum toxin A in reducing overall limb pain in patients with complex regional pain syndrome (CRPS). Additionally the investigators would like to see if quality of life is improved and disability scores decreased. Research Design: This is a double blinded, randomized cross-over study that will be conducted over a 7 month period. It is a pilot study that will include twenty subjects recruited from the Neurology CRPS clinic at VA Connecticut and from outside VA hospitals within a 150 mile radius. Subjects will receive an intramuscular injection Treatment A which is only 1% lidocaine or Treatment B which is mixture of botulinum toxin A + 1% lidocaine in the affected limb only. This is a cross over study where patients will receive Treatment A or B initially during the first of four study visits and during the third study visit while receive whichever treatment not given during the first visit. Dr. Sameer Ali, VA neurology fellow, will be blinded when administering the treatments. Dr. Hajime Tokuno, VA neurologist who is the principal investigator of the trial will prepare the treatments. Clinical pharmacy will be randomizing the treatments. Dr. Tokuno will not be blinded as he needs to know which treatment has been given in case of complications. Impact/Significance: The significance of this study is the possible discovery of a new, safer, less invasive, and more efficacious therapeutic option for patients suffering from CRPS. Currently medical management with neuropathic pain meds, interventions such as sympathetic nerve blocks and ketamine infusion has helped some patients and not others. The investigators are trying to see whether either of the two treatments and especially the treatment with botulinum toxin may be a more viable alternative than existing modalities.
Behavioral Intervention
Graded Motor Imagery for Complex Regional Pain Syndrome Prevention After Wrist Fracture
This trial will test whether graded motor imagery can help prevent complex regional pain syndrome, a painful condition that can develop after a forearm fracture.
View More Complex Regional Pain Syndrome Trials
See another 2 medical studies focused on complex regional pain syndrome.
Frequently Asked Questions
Introduction to complex regional pain syndrome
What are the top hospitals conducting complex regional pain syndrome research?
Complex regional pain syndrome (CRPS) is a debilitating condition that affects a patient's nervous system, causing severe and chronic pain. In the quest for effective treatments and interventions, several top hospitals are leading the way in conducting clinical trials dedicated to CRPS. Stanford University, situated in Palo Alto and Stanford, has emerged as a frontrunner with its ongoing commitment to addressing this complex and challenging disorder. Currently, they have two active trials focused on CRPS, building upon their previous two studies since undertaking their initial trial in 2015. Meanwhile, the University of Washington in Seattle has made notable strides by exclusively offering clinical trials specifically tailored to CRPS patients; their dedication includes an ongoing trial and one previously conducted study starting from 2022.
Furthermore, groundbreaking efforts can be witnessed at the Fralin Biomedical Research Institute located in Roanoke where they are actively pursuing one trial targeting complex regional pain syndrome while also having completed another investigation since initiating research endeavors into this condition just last year—2023.Though relatively new to the field compared to other institutions mentioned here,the UCSF Medical Center based out of San Francisco showcases equal determination with its present-day engagement in an ongoing clinical trial alongside gainful utilization of opportunities provided by their past singular investigations beginning from 2022 onwards.
These hospitals' unwavering dedication towards advancing our understanding of CRPS demonstrates a commitment to improving the lives of those living with this excruciating condition. By pioneering innovative approaches through rigorous scientific investigations,collaborating across specialties,and employing cutting-edge technologies these institutions endeavor not only provide much-needed relief but also strive toward finding long-lasting solutions for a better quality life for individuals battling Complex Regional Pain Syndrome
Which are the best cities for complex regional pain syndrome clinical trials?
When it comes to clinical trials for complex regional pain syndrome, several cities are leading the way in research and treatment options. Palo Alto, California and San Francisco, California both have 2 active trials each, focusing on interventions such as Empowered Relief for Youth, LDN, High Frequency rTMS, Active DBS. Additionally, Stanford University in California has 1 active trial investigating treatments like Ketamine and Midazolam. Seattle in Washington also has 1 ongoing trial exploring Roosevelt "in Clinic VR" + "VR homeworks". Finally, Roanoke in Virginia offers 1 active trial studying LIFU - CRPS. These cities serve as hubs of innovation and provide individuals with complex regional pain syndrome access to cutting-edge clinical trials that offer hope for improved outcomes and relief from their condition.
Which are the top treatments for complex regional pain syndrome being explored in clinical trials?
Clinical trials exploring treatments for complex regional pain syndrome (CRPS) have identified two top contenders. First on the list is Empowered Relief for Youth, which has shown promise in its ongoing trial specifically targeting CRPS. Introduced in 2023, this treatment aims to provide relief and improvement for young patients suffering from this debilitating condition. Another contender making waves is High Frequency rTMS, with an active trial dedicated to investigating its effectiveness against CRPS. This innovative therapy was first listed in 2022 and holds potential as a non-invasive option for managing the symptoms of CRPS. As research progresses, these treatments offer hope for individuals living with the burdensome challenges of CRPS.
What are the most recent clinical trials for complex regional pain syndrome?
In the realm of complex regional pain syndrome (CRPS), recent clinical trials have focused on exploring the potential benefits of ketamine and midazolam. In a Phase 2 trial, these medications are being investigated for their effectiveness in alleviating the symptoms associated with CRPS. By targeting and managing the unique challenges posed by this condition, researchers aim to enhance patient outcomes and provide relief from chronic pain. With ongoing studies delving into innovative treatment approaches, there is hope for improved quality of life for individuals battling CRPS.
What complex regional pain syndrome clinical trials were recently completed?
Recently completed clinical trials have made significant progress in the field of complex regional pain syndrome (CRPS). These trials aimed to enhance our understanding and develop improved treatments for this debilitating condition. One notable trial was sponsored by the National Institute of Neurological Disorders and Stroke, which explored new therapeutic approaches and concluded recently. Another important study, conducted by Johns Hopkins University School of Medicine, examined the effectiveness of a novel intervention technique on CRPS symptoms. These successful advancements offer hope to individuals living with CRPS and highlight the ongoing efforts to find better solutions for managing this challenging condition.