Myeloma Clinical Trials
Here are the 6 most popular medical studies for myeloma
Proteasome Inhibitor
BLd Combination Therapy for Multiple Myeloma
This trial is testing a new combination therapy for multiple myeloma. The goal is to find the highest dose of the combination that can be given safely, and to see how well it works in newly diagnosed patients.
Bexxar therapeutic for Multiple Myeloma
This trial is for patients with newly diagnosed or relapsed multiple myeloma who will receive consolidation treatment with Bexxar, a radioactive antibody. The study will look at how patients respond to the treatment and what side effects occur.
Proteasome Inhibitor
Chemotherapy + Stem Cell Transplant for Multiple Myeloma
This trial is studying the side effects and best dose of bortezomib when given together with fludarabine phosphate and melphalan with or without total marrow irradiation for patients with high-risk stage I or II multiple myeloma.
Monoclonal Antibodies
PD-1 Blockade + Dendritic Cell Fusion Vaccine + CT-011 for Multiple Myeloma
This trial is testing the safety of CT-011 and the combination of the Dendritic cell fusion vaccine and CT-011 after ASCT in patients with multiple myeloma. They are also testing to see if the combination is more successful in preventing or delaying the disease from coming back, compared to treatment with ASCT alone.
Popular filter options for myeloma trials
Multiple Myeloma Clinical Trials
View 87 Multiple Myeloma medical studies.
Alkylating agents
Melphalan + Prednisone + Thalidomide/Lenalidomide for Multiple Myeloma
This trial compares melphalan/prednisone with thalidomide to melphalan/prednisone with lenalidomide to see which is more effective in treating newly diagnosed multiple myeloma.
MM (Multiple Myeloma) Clinical Trials
View 87 MM (Multiple Myeloma) medical studies.
Alkylating agents
Melphalan + Prednisone + Thalidomide/Lenalidomide for Multiple Myeloma
This trial compares melphalan/prednisone with thalidomide to melphalan/prednisone with lenalidomide to see which is more effective in treating newly diagnosed multiple myeloma.
Phase 3 Myeloma Clinical Trials
View 89 phase 3 myeloma medical studies.
Alkylating agents
Melphalan + Prednisone + Thalidomide/Lenalidomide for Multiple Myeloma
This trial compares melphalan/prednisone with thalidomide to melphalan/prednisone with lenalidomide to see which is more effective in treating newly diagnosed multiple myeloma.
Immunomodulatory Agent
Lenalidomide for Smoldering Multiple Myeloma
This trial compares lenalidomide to observation in treating patients with asymptomatic high-risk multiple myeloma. It is not yet known whether lenalidomide is more effective than observation alone.
Myeloma Clinical Trials With No Placebo
View 89 myeloma medical studies that do not have a placebo group.
Alkylating agents
Melphalan + Prednisone + Thalidomide/Lenalidomide for Multiple Myeloma
This trial compares melphalan/prednisone with thalidomide to melphalan/prednisone with lenalidomide to see which is more effective in treating newly diagnosed multiple myeloma.
View More Myeloma Trials
See another 69 medical studies focused on myeloma.
Frequently Asked Questions
Introduction to myeloma
What are the top hospitals conducting myeloma research?
When it comes to innovative clinical trials in the treatment of myeloma, several leading hospitals are pushing boundaries and offering hope. Memorial Sloan Kettering Cancer Center in New york is at the forefront with 12 active myeloma trials, demonstrating their commitment to finding breakthroughs for this challenging condition. While they may not have any previous myeloma trials on record, their dedication to ongoing research sets them apart. In Denver, the Colorado Blood Cancer Institute is making significant strides with nine current myeloma trials. The absence of past trials does not diminish their efforts in advancing treatment options for patients with this blood cancer.
The Mayo Clinic in Rochester is also actively involved in tackling myeloma through eight ongoing clinical trials. Their expertise and experience across various medical specialties make them a trusted institution when it comes to exploring new avenues for treating this disease. Similarly, the Levine Cancer Institute in Charlotte ensures that six active clinical trials are underway to provide patients with cutting-edge options and improved outcomes.
Notably, Massachusetts General Hospital in Boston contributes its expertise by conducting five active myeloma trials despite having no all-time records so far.These esteemed institutions illustrate how collaboration between dedicated researchers leads us closer towards effective treatments for those battling against myeloma—an aggressive form of blood cancer characterized by abnormal plasma cell growth within bone marrow.The collective effort made by these top hospitals instills hope among patients worldwide while reinforcing our belief that scientific advancements hold immense potential to transform lives affected by such diseases as we collectively strive toward a healthier tomorrow
Which are the best cities for myeloma clinical trials?
When it comes to myeloma clinical trials, several cities are at the forefront of research and development. New york leads the way with 55 active trials focusing on treatments like CC-95266, bb2121, and ISB 1342. Denver follows closely behind with 43 ongoing studies investigating medications such as Lenalidomide, Bortezomib, and Cohort D1 and D2: maplirpacept (PF-07901801) + an anti-CD20 targeting agent. Lastly, Boston and Atlanta both offer promising opportunities for myeloma patients with 31 and 29 active trials respectively examining various treatment approaches including Isatuximab SAR650984, Belantamab mafodotin, TEG002, Lenalidomide, ixazomib,and bb2121. These cities serve as hubs for cutting-edge clinical research that can potentially improve outcomes for individuals battling myeloma.
Which are the top treatments for myeloma being explored in clinical trials?
Clinical trials for myeloma are uncovering promising treatments that hold potential for patients fighting this challenging disease. One standout therapy is daratumumab, currently being investigated in multiple trials and showing encouraging results. Another contender making waves is belantamab mafodotin, with its innovative approach gaining attention in ongoing research studies. Finally, lenalidomide has proven its worth over time and remains a top option under investigation as well. These three treatments are at the forefront of myeloma clinical trials, offering hope for improved outcomes and quality of life for patients in the future.
What are the most recent clinical trials for myeloma?
Exciting advancements are occurring in the realm of myeloma treatment, with recent clinical trials providing promising findings. Notable studies include Arm A, a Phase 3 trial exploring new therapeutic approaches for myeloma patients. Additionally, Teclistamab, an investigational therapy currently in Phase 3 clinical trials, shows potential as a treatment option. Another trial worth mentioning is KTX-1001, which is investigating innovative methods to combat myeloma and has entered Phase 1. These trials signify significant progress towards improving outcomes and enhancing quality of life for individuals affected by this disease.
What myeloma clinical trials were recently completed?
Recent clinical trials focusing on myeloma have made significant strides in advancing treatments for this challenging condition. In October 2021, a trial sponsored by Washington University School of Medicine concluded, evaluating the effectiveness of Uproleselan against myeloma. Another notable trial completed in September 2021 was led by the National Cancer Institute and investigated mRNA-1273 as a potential therapy option. Additionally, AgenTus Therapeutics wrapped up their agenT-797 study in January 2021. These exciting developments highlight the commitment of researchers to find innovative solutions for myeloma patients.