PCOS Clinical Trials
Here are the 6 most popular medical studies for pcos
Dietary Supplement
Myo-Inositol + Letrozole for PCOS Infertility
This trial will compare the effect of letrozole with a placebo, versus letrozole with inositols, on pregnancy rates in women undergoing ovulation induction. The trial will be double-blind, meaning that neither the participants nor the research team will know which treatment each person is receiving.
Biguanides
Metformin vs. Birth Control Pills for Polycystic Ovary Syndrome
This trial will compare metformin to oral combined hormonal contraceptives in treating Polycystic Ovary Syndrome in women of later reproductive age, using the Polycystic Ovary Syndrome Questionnaire score as a proxy for patient satisfaction.
Popular filter options for pcos trials
PCOS Clinical Trials
View 42 PCOS medical studies.
Beta3-Adrenergic Receptor Agonist
Mirabegron + B Complex Plus Vitamin C for Brown Adipose Tissue
This trial is testing if brown adipose tissue (BAT) can help the body burn energy. Healthy people ages 18-40 with a body mass index between 18 and 40 may be eligible. Participants will take 2-4 pills daily for 4 weeks.
Biguanide
Metformin for Polycystic Ovary Syndrome
This trial is assessing the efficacy of metformin for hepatic fat in adolescents and young adults with polycystic ovary syndrome (PCOS). PCOS is a common condition that frequently presents in adolescence and young adulthood, and is associated with insulin resistance, NAFLD, and lipid abnormalities. Metformin is an insulin sensitizing medication that is widely used to treat type 2 diabetes mellitus, and may have beneficial effects on PCOS and NAFLD.
Behavioral Intervention
Fitness Support Group Program for Obesity
This trial is testing a program to get girls to exercise more and enjoy it more. They will do this by measuring how much they enjoy it before and after the program, as well as how it affects their risk for diseases.
Progestogen
Progesterone for Normal Puberty
This trial is testing whether or not giving progesterone to pubertal girls will prevent the nighttime increase of LH pulses. If successful, this could help researchers understand more about how menstrual cycles are established.
Metabolic Syndrome Clinical Trials
View 15 Metabolic Syndrome medical studies.
Biguanide
Metformin for Polycystic Ovary Syndrome
This trial is assessing the efficacy of metformin for hepatic fat in adolescents and young adults with polycystic ovary syndrome (PCOS). PCOS is a common condition that frequently presents in adolescence and young adulthood, and is associated with insulin resistance, NAFLD, and lipid abnormalities. Metformin is an insulin sensitizing medication that is widely used to treat type 2 diabetes mellitus, and may have beneficial effects on PCOS and NAFLD.
Behavioral Intervention
Fitness Support Group Program for Obesity
This trial is testing a program to get girls to exercise more and enjoy it more. They will do this by measuring how much they enjoy it before and after the program, as well as how it affects their risk for diseases.
Polycystic Ovarian Syndrome Clinical Trials With No Placebo
View 43 polycystic ovarian syndrome medical studies that do not have a placebo group.
Behavioral Intervention
Fitness Support Group Program for Obesity
This trial is testing a program to get girls to exercise more and enjoy it more. They will do this by measuring how much they enjoy it before and after the program, as well as how it affects their risk for diseases.
View More Pcos Trials
See another 22 medical studies focused on pcos.
Frequently Asked Questions
Introduction to pcos
What are the top hospitals conducting pcos research?
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder affecting millions of women worldwide. In the pursuit of effective treatments and advancements in understanding this condition, several leading hospitals have emerged as frontrunners in conducting clinical trials dedicated to PCOS research. The University of Virginia in Charlottesville, renowned for its expertise in reproductive health, takes top billing with six active PCOS trials and seven historically completed studies. Since their first recorded trial back in 2000, researchers at this esteemed institution have been committed to unraveling the mysteries surrounding PCOS.
Not far behind is Massachusetts General Hospital located in Boston, whose three ongoing PCOS trials demonstrate their commitment to advancing healthcare outcomes for those affected by this disorder. Though they may have fewer historical trials under their belt—three to be exact—the hospital's dedication to exploring innovative solutions shines through since recording their inaugural trial focused on PCOS management just over a decade ago, in 2009.
In addition to these remarkable institutions' contributions towards understanding and treating PCOS, the University of Virginia Center for Research in Reproduction has also made significant strides. With three active clinical trials dedicated specifically to PCOS currently underway and an impressive total of eight previous investigations conducted since initiating their first trial related to this condition back in 2006.
Meanwhile, another arm affiliated with the University of Virginia that deserves recognition is the Center for Research on Reproduction which boasts two ongoing clinical tests targeting PCOS while having contributed significantly through conducting preceding six experiments from starting its pioneering investigation on such cases way back until 2006. And last but not least - making valuable contributions relatively recently- The University of Virginia Clinical Research Unit joins forces with two active pcos clincal projects alongwith previously executed two more; theirs can be traced back only five years ago,in2016.
These notable hospitals situated across Charlottesville and Boston are collectively striving towards conquering polycystic ovary syndrome by pushing the boundaries of medical research and treatment options. Their tireless efforts illuminate a path towards better understanding, improved management, and ultimately enhanced quality of life for women living with PCOS around the globe.
Which are the best cities for pcos clinical trials?
Charlottesville, Virginia; Boston, Massachusetts; San Francisco, California; Chicago, Illinois; and Davenport, Iowa are among the top cities for PCOS clinical trials. In Charlottesville, there are 13 active trials focusing on medications like Metformin, Spironolactone, and Flutamide. Similarly in Boston and San Francisco, researchers are investigating various treatments including kisspeptin, GnRH, Tildacerfont, CPAP groups and vigorous exercise interventions. Meanwhile in Chicago and Davenport studies center around Salsalate use for PCOS management along with other interventions like Letrozole and time-restricted eating (TRE). These cities offer individuals with PCOS access to cutting-edge research aimed at improving treatment options for this common endocrine disorder.
Which are the top treatments for pcos being explored in clinical trials?
Clinical trials are actively exploring potential treatments for polycystic ovary syndrome (PCOS). Metformin, a well-known medication, is currently being tested in four ongoing trials dedicated to PCOS. Since its introduction in 2000, it has been involved in a total of 76 clinical trials related to this condition. Another treatment under investigation is spironolactone, which is being studied in two active PCOS trials and has been listed since 2016. Additionally, flutamide shows promise as a potential therapy with two active PCOS trials and five all-time clinical trials since its first listing in 2006. Continued research into these treatments offers hope for managing the challenging symptoms associated with PCOS.
What are the most recent clinical trials for pcos?
Exciting advancements are being made in the field of polycystic ovary syndrome (PCOS) research, with recent clinical trials shedding light on potential treatment options. One such trial focuses on kisspeptin and GnRH as a means to address PCOS symptoms. Another study explores the effectiveness of tildacerfont in managing the condition. Additionally, letrozole has been investigated for its impact on PCOS patients during Phase 4 trials. Similarly, an ongoing Phase 4 trial is evaluating the use of etonogestrel/ethinyl estradiol vaginal ring in individuals with PCOS. Lastly, promising results have emerged from a Phase 2 trial examining the efficacy of inositol for treating this complex condition. These latest clinical trials offer hope and promise for those affected by PCOS, bringing us closer to improved management strategies and better quality of life for patients.
What pcos clinical trials were recently completed?
Recently completed clinical trials focusing on polycystic ovary syndrome (PCOS) have provided valuable insights into potential treatments for this complex condition. In December 2017, Yale University concluded a trial investigating the use of GnRH antagonists as a therapeutic approach. Meanwhile, in August 2014, researchers at the University of Colorado, Denver completed a trial studying the effectiveness of Byetta 5Mcg Pen Injection. Additionally, in April 2013, the University of California, Los Angeles wrapped up their study on Flutamide's impact on PCOS management. These important studies enhance our understanding and pave the way for future advancements in addressing PCOS-related challenges faced by women worldwide.