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PET Imaging for Glioblastoma
Study Summary
This trial will use a PET scanner to test an improved method for differentiating tumor recurrence from radiation necrosis in glioblastoma patients. The new quantitative kinetic analytical methods using FDOPA in combination with FDG will provide crucial functional information to distinguish recurrent tumors from treatment-induced radiation changes in patients with treated brain neoplasms.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am a woman who is either postmenopausal or have had surgery to prevent pregnancy.I have or might have a recurring brain tumor.I am not allergic to 18F-FDOPA or 18F-FDG.I haven't consumed sugar, caffeine, or any calories 4 hours before a PET scan and can lie flat for an hour.I am willing and able to follow the study's schedule and procedures.My MRI shows my condition worsened within 3 months after radiation and temozolomide therapy.I am a woman who could potentially become pregnant.I need a PET-CT scan as advised by my doctor.I am older than 18 years.My tumor is located in a specific part of my brain.I have not changed my medication or dosage between my first and second visits.I can lie flat and still for at least 60 minutes.
- Group 1: Diagnostic
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is recruitment for this research still open?
"Affirmative. Current information on clinicaltrials.gov shows that the trial, which was first initiated on March 15th 2020 is still actively recruiting participants with a goal of enrolling 5 patients from one medical centre."
What is the scope of participants in this clinical trial?
"Affirmative. Clinicaltrials.gov displays that the clinical trial, which was initially shared on March 15th 2020, is actively searching for participants. 5 people are needed at one location to complete this research project."
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