← Back to Search

Temporo-masseteric Nerve Block for Acute Pain

Phase 2
Recruiting
Led By Gayathri D Subramanian, PhD, DMD
Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, post-procedure (day 1) and at post-operative visit (day 8)
Awards & highlights

Study Summary

This trial is testing whether a nerve block can reduce pain for people getting their lower wisdom teeth removed while sedated. People will be asked about their pain and pain meds use for a week after the procedure, and then checked in on 8 days later.

Who is the study for?
This trial is for adults aged 18-64 who need their lower wisdom teeth removed and can consent to the study. They must be healthy enough for sedation, not pregnant, have internet access with a smartphone, and able to take common pain meds like Tylenol or Advil.Check my eligibility
What is being tested?
The study tests if a local anesthetic injection called Temporo-masseteric Nerve Block reduces pain after wisdom tooth removal under sedation. Participants will report their pain levels and medication use over the first week post-surgery.See study design
What are the potential side effects?
Potential side effects may include discomfort at the injection site, possible allergic reactions to the anesthetic used in the nerve block, and typical risks associated with dental procedures such as swelling or infection.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, post-procedure (day 1) and at post-operative visit (day 8)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-procedure (day 1) and at post-operative visit (day 8) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adverse effects
Masticatory muscle pain to palpation- Temporalis and Masseter
Mean Numerical Pain Rating Scale pain score
+3 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Temporo-masseteric Nerve Block (TMNB) Injection with Local AnestheticExperimental Treatment1 Intervention
Following lower third molar extraction under intravenous sedation, the patient will receive the TMNB local anesthetic nerve block using the standard dental local anesthetic, i.e,. 2% lidocaine with 1:100,000 epinephrine, on the side/s of lower wisdom molar extraction/s

Find a Location

Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor
432 Previous Clinical Trials
64,798 Total Patients Enrolled
2 Trials studying Acute Pain
144 Patients Enrolled for Acute Pain
Gayathri D Subramanian, PhD, DMDPrincipal InvestigatorRutgers School of Dental Medicine
~3 spots leftby Nov 2024
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top