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Topical Ruxolitinib for Hand Eczema
Study Summary
This trial will test whether Ruxolitinib, a topical medication, is effective in treating Chronic Hand Dermatitis. The trial will be conducted at the University of Rochester Medical Center in Rochester, New York, and will require subjects to come to the URMC Dermatology Clinic for at least five visits.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 3 trial • 149 Patients • NCT02038036Trial Design
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- I have had skin cancer on my hands in the last 5 years.I haven't used any antibiotic creams on my hands in the last 2 weeks.I am not pregnant, breastfeeding, or planning to become pregnant during the study.I have previously received JAK inhibitor therapy.I haven't taken any immune-suppressing drugs or steroids in the last 4 weeks.You have a low blood cell count that is concerning to the doctors.I haven't used any skin treatments on my hands, except my own moisturizers, in the last week.I haven't taken any experimental or approved biologic drugs in the last 6 months.You have a known allergy to a specific substance and cannot avoid contact with it.My liver or kidney function is severely impaired and not stable.My condition is considered moderate to severe.I have had hand eczema for over 3 months or it has come back twice in the last year.I haven't started or changed my antihistamine dose in the last 2 weeks.I do not have HIV or any primary immunodeficiency disorder.I have not taken antibiotics in the last 4 weeks.I have not had light therapy on my hands in the last 4 weeks.I haven't used any skin immune creams or steroids on my hands in the last 2 weeks.I have a serious infection on my hands.Topical treatments haven't worked for me in the past year, or I can't use them for health reasons.I have skin inflammation needing treatment, not just on my hands.I have psoriasis needing treatment, not just on my hands.My hand dermatitis is mainly due to my hands being in water for over 2 hours a day or washing them more than 20 times a day.I have had stubborn warts on my hands in the past year.
- Group 1: All Participants
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are being included in this experiment?
"Affirmative. Records on clinicaltrials.gov verify that this research trial, which was initially uploaded to the website on July 11th 2022, is actively recruiting individuals for participation. Only 15 volunteers need to be sourced from a single medical centre."
Is enrollment still an option for this research endeavor?
"Affirmative. According to information hosted on clinicaltrials.gov, this research is currently enrolling individuals; the initial posting was published on July 11th 2022 and most recently updated August 9th 2022. The trial seeks 15 participants from one medical centre."
Is there any way I can participate in this research?
"This clinical trial is recruiting 15 volunteers, aged 18-75 years old that are suffering from chronic dermatitis. Specifically, the disease severity must have been graded as moderate to severe via IGA and participants must also have unsuccessfully attempted treatment with corticosteroids or calcineurin inhibitors in the past year prior to screening for this study."
Is the minimum age requirement for this trial less than 80 years old?
"To be considered for this trial, potential participants must fall between the age range of 18 and 75. For those younger than 18 years old or over 65, there are 96 clinical trials to explore and 153 studies respectively."
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