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Evomela + Fludarabine + TBI for Multiple Myeloma
Study Summary
This trial is testing a new cancer treatment that uses a different form of melphalan than what is typically used, in combination with fludarabine and total-body irradiation-based reduced-intensity conditioning, in order to see if it is effective and safe.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 3 trial • 30 Patients • NCT01877837Trial Design
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Who is running the clinical trial?
Media Library
- Group 1: MEL/FLU and Total-Body Irradiation (TBI)
Frequently Asked Questions
How many volunteers have enrolled in this clinical research?
"Affirmatively, the information hosted on clinicaltrials.gov proves that this trial is actively enrolling patients; it was first posted on December 8th 2017 and recently adjusted on October 4th 2022 with a goal of recruiting 43 participants from 1 medical centre."
To what extent does Fludarabine pose a threat to human health?
"Our team at Power rated the safety of Fludarabine as a 2 in light of this Phase 2 clinical trial which has some evidence supporting its security profile, yet no data confirming efficacy."
Is recruitment for this experiment still taking place?
"Indeed, the clinicaltrials.gov database reveals that this medical trial is still open for recruitment and was first released on 8th December 2017. The study has since been updated on 4th October 2022 and seeks 43 participants from one single site."
What are the desired results of this research endeavor?
"This biomedical investigation, lasting approximately one year, will monitor Progression-Free Survival (PFS) among patients with hematological malignancies. Secondary endpoints include Neutrophil Recovery time, Primary Graft failure rate, and Number of Relapsed Disease instances."
How is Fludarabine commonly employed in medicine?
"Fludarabine has been demonstrated to have therapeutic value in the management of chronic lymphocytic leukemia, stem cell transplantation and amyloidosis."
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