Your session is about to expire
← Back to Search
FGF-2 for Ear Drum Perforation
Study Summary
This trial is testing whether or not a growth factor called FGF-2 can help heal chronic non-healing tympanic membrane perforations (TMP). The main way they will measure efficacy is by documentation of TM closure. The study will have two phases- during the first phase, subjects will be randomly assigned to receive FGF-2 or placebo, and in the second phase, subjects who did not respond to the initial treatment will receive the other treatment.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 2 trial • 57 Patients • NCT02307916Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- My tissue damage is due to a burn or radiation therapy.I have issues with the bones in my ear.I have a growth or invasion in my ear's inner parts.I am currently on radiation, steroids, immunosuppressants, or chemotherapy.I currently have an ear infection or chronic ear discharge.I am currently taking antibiotics.I have a tumor with an abnormal shape or form.I currently have or recently had a bacterial or viral infection.I have had ear canal cancer in the last 3 years.I am 18 years old or older.I have had surgery to repair my eardrum.My diabetes is not well-controlled (HbA1c 6.9% or higher).I have moderate to severe dementia, like Alzheimer's.I have had a hole in my eardrum for at least 6 months.
- Group 1: Placebo
- Group 2: Human Fibroblast Growth Factor-2 (FGF-2)
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research endeavor actively enrolling new participants?
"Data available on clinicaltrials.gov demonstrates that this experiment is actively seeking new participants since its initial posting on May 27th 2022 and subsequent editing on June 7th 2022."
Does FGF-2 pose any risk to patients when administered?
"Although FGF-2 has only been tested on a limited basis for its safety, it received an estimation of 2 out of 3 due to the Phase 2 trial data that supports it."
How many individuals is this trial recruiting?
"Affirmative. According to the information hosted by clinicaltrials.gov, this investigation is actively seeking out volunteers, having been initially posted on May 27th of 2022 and most recently updated on June 7th of that same year. 70 individuals from a single site are necessary for completion of the trial."
Are there other investigations that have taken place regarding FGF-2?
"Currently, 3 clinical trials are running to evaluate the efficacy of FGF-2. None of these active studies have advanced to Phase 3 yet and most locations for testing this treatment can be found in Nanjing, Jiangsu; though there is a total of three sites supporting these experiments."
Share this study with friends
Copy Link
Messenger