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Proton vs. Photon Therapy for Breast Cancer
Study Summary
This trial is testing whether proton therapy or photon therapy is better for treating breast cancer. It will follow patients for side effects, quality of life, and cancer control.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- There is clear proof from the doctor or scans that the cancer has spread to other parts of the body.I have had radiation therapy on the same side as my current breast or chest cancer.I have not received radiation for my current breast cancer before joining this study.I am scheduled for radiation therapy on my breast/chest and lymph nodes, including the internal mammary nodes.I have been diagnosed with breast cancer and have had surgery to remove it.I have dermatomyositis with high CPK levels or an active rash, or I have scleroderma.I don't have any other serious illnesses that would stop me from participating in the study.I have non-metastatic breast cancer at stage I, II, III, or loco-regionally recurrent.I have cancer in both breasts and will be considered as having left-sided breast cancer.I have had a lumpectomy and any form of breast reconstruction or none at all.My breast size does not limit my eligibility after lumpectomy.I am HIV positive, on HAART, and my CD4 count is ≥ 200.I had a medical check-up relevant to my condition within the last 90 days.My health insurance will cover the study's treatment, but I can pay for some costs if needed.I am 21 years old or older.I've been mostly able to care for myself in the last 3 months.
- Group 1: Photon
- Group 2: Proton
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are enrolled in this medical trial?
"To complete this clinical trial, 1278 qualified individuals are required to take part. Participants can join from the University of Florida Health Proton Therapy Institute in Jacksonville, or at Abramson Cancer Center of the University of Pennsylvania in Philadelphia."
How many research centers are currently conducting this experiment?
"This clinical trial is enlisting participants at 27 sites such as University of Florida Health Proton Therapy Institute in Jacksonville, Abramson Cancer Center of the University of Pennsylvania in Philadelphia, and University Pointe, University of Cincinnati in Hamilton. Additionally there are 24 other recruiting locations throughout the nation."
Is access to this experiment currently available for participants?
"Affirmative. According to the clinicaltrials.gov database, this trial has been recruiting since February 1st 2016 and was recently modified on November 18th 2022. A total of 1278 subjects are needed from 27 healthcare facilities for enrollment in this study."
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