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Focused Ultrasound
Focused Ultrasound for Obsessive-Compulsive Disorder
N/A
Waitlist Available
Led By Sheldon Jordan, MD
Research Sponsored by Neurological Associates of West Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Failure to remit with 3 SSRIs, antidepressants and/or anxiolytics
At least 18 years of age
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks from baseline
Awards & highlights
Study Summary
This trial will test whether using ultrasound waves can help treat people with OCD. The goal is to find out if it is safe and effective.
Who is the study for?
This trial is for adults with Obsessive-Compulsive Disorder who haven't improved after trying at least three different SSRIs, antidepressants, or anxiolytics. Participants must speak English, follow the study rules, and have a moderate to severe OCD diagnosis as indicated by scoring over 15 on the Y-BOCS.Check my eligibility
What is being tested?
The trial is testing focused ultrasound treatment's safety and effectiveness in treating OCD. It aims to see if this non-invasive method can help where traditional medications have failed.See study design
What are the potential side effects?
While not explicitly listed here, potential side effects of focused ultrasound may include discomfort at the treatment site, headache or dizziness during or after treatment. Long-term side effects are being studied.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have tried 3 different SSRIs without improvement in my condition.
Select...
I am 18 years old or older.
Select...
I have been diagnosed with Obsessive Compulsive Disorder.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 8 weeks from baseline
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks from baseline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Secondary outcome measures
Anxiety
Beck Depression Inventory (BDI-II)
Global Rating of Change (GRC)
+1 moreTrial Design
1Treatment groups
Experimental Treatment
Group I: ActiveExperimental Treatment1 Intervention
Patients will undergo ten to thirty minutes of transcranial ultrasound treatment. The sonification device will be aimed at the caudate. Targeting will include reference to scalp fiducials based on the obtained MRI; confirmation of target accuracy will either be obtained by Doppler waveform confirmation or optical tracking technology which co-registers patient neuroimaging with real space.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Focused Ultrasound
2012
Completed Phase 2
~50
Find a Location
Who is running the clinical trial?
Neurological Associates of West Los AngelesLead Sponsor
25 Previous Clinical Trials
3,930 Total Patients Enrolled
Sheldon Jordan, MDPrincipal InvestigatorNeurological Associates of West LA
12 Previous Clinical Trials
2,560 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am currently receiving treatment for cancer.I have a condition that involves abnormal growth of blood vessels.I am unable to understand and give consent for treatment.I have tried 3 different SSRIs without improvement in my condition.I am 18 years old or older.I am not proficient in English.I have been diagnosed with Obsessive Compulsive Disorder.I can't stay still enough to fall asleep in a calm environment.I have severe kidney, lung, heart, or liver disease.I have macular degeneration.I have a scalp rash or open wounds on my scalp.
Research Study Groups:
This trial has the following groups:- Group 1: Active
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is this experiment open for enrolment?
"Data hosted on clinicaltrials.gov confirms that this medical study, first posted December 1st 2020 and last edited September 26th 2022, is no longer recruiting patients. However, there are 114 other trials currently seeking participants to join their experiments."
Answered by AI
Who else is applying?
What state do they live in?
Texas
Wisconsin
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0
What site did they apply to?
Neurological Associates of West LA
Neurological Associates of West Los Angeles
Why did patients apply to this trial?
I have harm ocd and it’s lonely I also have some relationship and germ type it is very lonely I can’t talk to anyone it seems about it but a therapist.
PatientReceived 2+ prior treatments
When it comes to things regarding health, and especially mental health, I am eager to learn. Especially with have been diagnosed with conditions myself. I can relate, and I'm always interested In gaining knowledge about the human body and trying to understand why I am who I am today.
PatientReceived no prior treatments
What questions have other patients asked about this trial?
How many visits?
PatientReceived 2+ prior treatments
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