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Diagnostic Imaging
Methodology for Heart Failure (LUPE Trial)
N/A
Waitlist Available
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1
Awards & highlights
LUPE Trial Summary
This trial will test whether lung ultrasound can be used to measure extravascular lung water in stabilized patients during hospitalization for acute heart failure.
Eligible Conditions
- Acute Heart Failure
LUPE Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ day 1
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in B-line score
LUPE Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Stable ADHF patientsExperimental Treatment1 Intervention
Lung ultrasound to access b lines
Group II: Control PatientsActive Control1 Intervention
Patients without any cardiopulmonary disease will be control patients for the active subjects, age-matched accordingly.
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Who is running the clinical trial?
University of PennsylvaniaLead Sponsor
2,012 Previous Clinical Trials
42,892,561 Total Patients Enrolled
42 Trials studying Heart Failure
7,499 Patients Enrolled for Heart Failure
GlaxoSmithKlineIndustry Sponsor
4,763 Previous Clinical Trials
8,104,698 Total Patients Enrolled
20 Trials studying Heart Failure
54,829 Patients Enrolled for Heart Failure
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You have serious lung conditions like severe chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, active asthma, or acute pneumonia.You have swelling in your ankles that leaves a slight pit when pressed on, but it goes away quickly.You can comfortably lie flat on your back with just one pillow (about 10 cm high) for at least 30 minutes without feeling short of breath, according to what you tell us.You are currently taking medications for COPD, such as inhalers or oxygen therapy.
Research Study Groups:
This trial has the following groups:- Group 1: Stable ADHF patients
- Group 2: Control Patients
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any current openings for this clinical experiment?
"According to the clinicaltrials.gov listing, this trial is no longer open for enrollment. Initially posted on May 4th 2017, it was last updated December 1st 2022 and subsequently closed. Despite that fact, there are still 703 other research projects looking for participants at present."
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