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Sprintec vs Ortho Tri Cyclen Lo
Introduction
In women seeking contraception or regulating their menstrual cycle, certain oral contraceptives that contain variations of the hormones estrogen and progestin can be highly effective. Sprintec and Ortho Tri-Cyclen Lo are two such drugs that are often prescribed. Both these medications contain synthetic forms of estrogen (ethinyl estradiol) and progestin (norgestimate), but in different concentrations.
Sprintec is a monophasic pill, meaning it provides the same level of hormones throughout the entire monthly cycle. On the other hand, Ortho Tri-Cyclen Lo is a triphasic pill, which means its hormone levels vary at three points during each month's regimen to more closely mimic a natural menstrual cycle.
Both options serve to prevent ovulation; however, they may have slightly different side effects due to their varying hormonal compositions and fluctuations throughout the cycle.
Sprintec vs Ortho Tri Cyclen Lo Side By Side
| Attribute | Sprintec | Ortho tri cyclen lo |
|---|---|---|
| Brand Name | Sprintec | Ortho Tri Cyclen Lo |
| Contraindications | Should not be used with certain Hepatitis C drug combinations (ombitasvir/paritaprevir/ritonavir with or without dasabuvir) due to potential increase in liver enzymes. Not recommended for use with some anticonvulsants and HIV/AIDS medications as they could make Sprintec less effective. | Should not be taken if you smoke cigarettes and are over 35 years old due to an increased risk for heart attacks, blood clots, and strokes. Similar to Sprintec, not recommended with certain Hepatitis C drug combinations and may be less effective with some anticonvulsants and HIV/AIDS medications. |
| Cost | Around $70 for a 28-day pack or $10-$20 for its generic version | Around $160 for a 28-pack supply or $30-$60 for its generic version |
| Generic Name | Norgestimate and ethinyl estradiol | Norgestimate/ethinyl estradiol |
| Most Serious Side Effect | Severe migraine headaches, chest pain indicating a heart attack, stroke signs like sudden numbness or weakness, vein inflammation due to blood clots. | Signs of an allergic reaction, severe headaches, blurred vision, chest pain indicating a possible heart attack, sudden cough or wheezing indicating possible blood clots in lungs, unusual weakness suggesting stroke. |
| Severe Drug Interactions | Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir with or without dasabuvir. | Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir with or without dasabuvir. |
| Typical Dose | One active pill per day for the first 21 days followed by seven inactive or 'reminder' pills. | 25 mcg of ethinyl estradiol and varying amounts of norgestimate (0.18 mg to 0.215 mg to 0.25 mg) in the three different types of active pills over a period of three weeks, followed by hormone-free 'reminder' pills. |
What is Sprintec?
Sprintec (a generic form of the Ortho-Cyclen) and Ortho Tri Cyclen Lo are both combination oral contraceptives that contain estrogen and progestin. These drugs mark a significant development in birth control options as they prevent ovulation, change the cervical mucus to make it harder for sperm to reach the egg, and alter the uterine lining to prevent attachment of a fertilized egg. Sprintec was first approved by the FDA in 1997. It contains higher levels of hormones compared to its counterpart, Ortho Tri Cyclen Lo, which may result in fewer breakthrough bleeding episodes but also possibly more side effects such as bloating or weight gain. Whilst both medications effectively prevent pregnancy when used correctly, individual side effect profiles and response can vary so choice often depends on personal preference and medical history.
What conditions is Sprintec approved to treat?
Sprintec is approved for use in the following areas:
- Prevention of pregnancy
- Treatment of moderate acne vulgaris in females at least 15 years old who have no known contraindications to oral contraceptive therapy and have achieved menarche
- Regulation of menstrual cycle
Ortho Tri Cyclen Lo has similar applications but with a lower dosage level for those sensitive to hormone levels.
How does Sprintec help with these illnesses?
Sprintec prevents pregnancy by altering the levels of estrogen and progesterone produced in a woman's body. It accomplishes this by introducing synthetic hormones which mimic these natural ones, tricking the body into believing it is already pregnant and thus preventing ovulation. Estrogen and progesterone are two primary female sex hormones that play crucial roles in menstrual cycle regulation, pregnancy, and the development of female secondary sexual characteristics among other things. Ortho Tri Cyclen Lo has a similar effect but with lower doses of these synthetic hormones than Sprintec. This can result in fewer side effects such as bloating or weight gain; however, it may also lead to more breakthrough bleeding (bleeding between periods) due to its low dose. Therefore, both drugs prevent pregnancy effectively but differ slightly on their hormonal concentration leading to potential differences in side-effects experienced.
What is Ortho Tri Cyclen Lo?
Ortho Tri-Cyclen Lo is a brand name for norgestimate/ethinyl estradiol, which is a combination hormonal contraceptive that prevents ovulation and thickens cervical mucus to hinder sperm from reaching any eggs. It also changes the lining of the uterus to prevent attachment of a fertilized egg. This drug was first approved by the FDA in 2002. As Ortho Tri-Cyclen Lo has lower doses of hormones compared to other oral contraceptives, its side-effect profile is slightly different from those with higher hormone levels like Sprintec. Whereas some users may experience bloating or weight gain with other contraceptives, Ortho Tri-Cyclen Lo's lower estrogen level can reduce such effects but may slightly increase breakthrough bleeding risk. The benefits of using this birth control include not only effective pregnancy prevention but also improvements in heavy periods and acne symptoms, especially in patients who do not respond well to "typical" high-dose contraceptive pills such as Sprintec.
What conditions is Ortho Tri Cyclen Lo approved to treat?
Ortho Tri-Cyclen Lo is an FDA-approved medication used for the prevention of pregnancy in women. It offers a lower dosage of hormones than some other birth control pills, making it a preferred choice for many women. The applications include:
- Pregnancy prevention
- Acne treatment for patients at least 15 years old who have started menstruating and need contraception
- Regulation of menstrual cycles
How does Ortho Tri Cyclen Lo help with these illnesses?
Ortho Tri-Cyclen Lo is a hormonal contraceptive that plays an important role in preventing pregnancy by suppressing the release of eggs from the ovaries, thickening cervical mucus to inhibit sperm movement and thinning uterine lining to prevent egg implantation. It contains a lower dose of hormones than some other birth control pills such as Sprintec, which may reduce certain side effects like nausea or weight gain. Furthermore, Ortho Tri-Cyclen Lo has a tri-phasic dosage schedule, meaning hormone levels vary throughout your cycle mimicking natural rhythm more closely than monophasic pills like Sprintec where hormone levels remain constant. This can potentially lead to fewer mood swings for some women. Just like with any medication though, individual responses vary and it's crucial to talk through these options with your healthcare provider.
How effective are both Sprintec and Ortho Tri Cyclen Lo?
Both Sprintec and Ortho Tri-Cyclen Lo are combination birth control pills, containing synthetic forms of estrogen and progestin to prevent ovulation. They were approved by the FDA in 2002 and 2001 respectively, so have a well-documented history of being safe and effective for contraception. Both serve as first-line options for hormonal birth control due to their high efficacy rates when used appropriately.
The effectiveness of Sprintec and Ortho Tri-Cyclen Lo was directly compared in several clinical trials. The two drugs exhibited similar efficacy in preventing pregnancy with typical use failure rates comparable to other combination oral contraceptive pills. No significant differences were noted between patients receiving either medication regarding breakthrough bleeding or spotting occurrences.
A review from 2014 showed that both medications are also commonly prescribed for off-label uses such as acne treatment, menstrual pain relief, premenstrual dysphoric disorder (PMDD) management, among others due to their favorable side effect profiles. Furthermore, they have been recognized for their role in reducing ovarian cyst formation risk.
Ortho Tri-Cyclen Lo is typically considered after standard dose combined oral contraceptive pills like Sprintec because it contains lower doses of hormones which may reduce some side effects but could lead to more breakthrough bleeding/spotting occurrences. Therefore it might be an optimal choice if women experience intolerable adverse effects on standard dose contraceptives or desire less hormone exposure while still maintaining reliable contraception.
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At what dose is Sprintec typically prescribed?
Oral dosages of Sprintec and Ortho Tri Cyclen Lo are both taken daily for 28 days, with one active pill per day for the first 21 days followed by seven inactive or "reminder" pills. The dosage of hormones in these birth control pills varies, but studies have indicated that both medications are effective in preventing pregnancy when taken as directed. It is important to take the pill at around the same time every day without skipping doses. If you miss a dose or if there's no bleeding during the week of inactive pills, consult your healthcare provider immediately as this could indicate a possible pregnancy. As with any medication, it’s crucial not to exceed prescribed dosages unless advised by your healthcare provider.
At what dose is Ortho Tri Cyclen Lo typically prescribed?
Ortho Tri-Cyclen Lo is a birth control pill that contains 25 mcg of ethinyl estradiol and varying amounts of norgestimate, ranging from 0.18 mg to 0.215 mg to 0.25 mg in the three different types of active pills over a period of three weeks. It's usually started on the first day of your menstrual cycle or on the first Sunday after your period begins, as directed by your healthcare provider. The dosage remains consistent throughout each week except for the final seven days which are hormone-free "reminder" pills, intended to maintain routine while allowing menstruation.
Remember that Ortho Tri-Cyclen Lo should not be taken if you smoke cigarettes and are over 35 years old due to an increased risk for heart attacks, blood clots and strokes. Always consult with your healthcare provider about any potential risks associated with hormonal contraception use.
What are the most common side effects for Sprintec?
Common side effects of Sprintec include:
- Nausea and vomiting
- Bloating
- Stomach cramps
- Changes in weight or appetite
- Breast tenderness or swelling
- Freckles or darkening of facial skin (melasma)
- Increased hair growth or loss of scalp hair
- Changes in menstrual periods, decreased sex drive
- Mild itching or rash
Ortho Tri Cyclen Lo can produce similar side effects. However, it's important to remember that each person may experience these differently. If you notice any unusual changes while on these medications, please consult with your healthcare provider for guidance.
Are there any potential serious side effects for Sprintec?
Sprintec and Ortho Tri Cyclen Lo are two different birth control pills that can sometimes cause serious side effects, although these cases are relatively rare. Potential severe reactions include:
- A sudden onset of wheezing, difficulty breathing or dizziness
- Swelling in the face, lips, tongue or other parts of the body
- Rash, itching or hives on the skin (indicative of an allergic reaction)
- Severe migraine headaches
- Problems with eyesight such as blurred vision or loss of vision
- Chest pain and discomfort which could indicate a heart attack
- Vein inflammation due to blood clots; symptoms may involve swelling, redness and heat in a leg vein
- Stroke signs like sudden numbness or weakness especially on one side of the body
If you experience any severe side effects while taking either Sprintec or Ortho Tri Cyclen Lo, it's recommended that you seek immediate medical attention. Always remember to inform your healthcare provider about any existing conditions before starting new medications.
What are the most common side effects for Ortho Tri Cyclen Lo?
Ortho Tri Cyclen Lo, a popular birth control pill, may cause the following side effects:
- Nausea or vomiting (initially), stomach cramps
- Mild headache or dizziness
- Breast tenderness and swelling
- Changes in weight or appetite
- Vaginal itching or discharge
- Decreased libido
- Mood changes, feelings of depression or anxiety.
Remember that these are potential side effects; not all users will experience them. In fact, many have found Ortho Tri Cyclen Lo to be effective with minimal discomfort. Always consult your doctor about any severe or persistent symptoms.
Are there any potential serious side effects for Ortho Tri Cyclen Lo?
Ortho Tri Cyclen Lo, while generally safe and effective as a contraceptive, can have rare but serious side effects. If you experience any of the following symptoms while on this medication, seek medical attention immediately:
- Signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue or throat
- Mood changes including depression or thoughts about suicide
- Severe headaches, blurred vision or seeing spots
- Lumps in the breast
- Jaundice (yellowing of the eyes/skin)
- Chest pain or heaviness that could indicate a possible heart attack
- Sudden cough or wheezing indicating possible blood clots in lungs
- Unusual weakness in one part or one side of body suggesting stroke.
Please note these are not common occurrences but it's important to be aware and consult with your healthcare provider if you notice anything unusual.
Contraindications for Sprintec and Ortho Tri Cyclen Lo?
Both Sprintec and Ortho Tri-Cyclen Lo are combination hormonal contraceptives that can, in some individuals, cause mood swings or symptoms of depression. Should you experience a significant shift in your emotional well-being or an increase in depressive thoughts while taking these medications, please seek immediate medical attention.
Neither Sprintec nor Ortho Tri-Cyclen Lo should be used if you are currently using certain other medications like Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir with or without dasabuvir as this may increase levels of liver enzymes. Always inform your healthcare provider about all the medicines you take; it is crucial to prevent dangerous interactions between drugs. Certain other drugs including anticonvulsants and HIV/AIDS medication could make Sprintec and Ortho Tri-Cyclen Lo less effective; consult your doctor before starting on any new medication while on birth control.
How much do Sprintec and Ortho Tri Cyclen Lo cost?
For brand-name versions of these drugs:
- The price for a 28-day pack of Sprintec averages around $70, which works out to approximately $2.50 per day.
- The cost of Ortho Tri-Cyclen Lo is significantly higher, averaging around $160 for a 28-pack supply or roughly $5.70 per day.
Thus, if you're considering the costs between these two birth control pills, Sprintec would be less expensive on a per-day treatment basis than Ortho Tri-Cyclen Lo. However, it's important to remember that cost should not be your primary consideration in determining which contraceptive drug is right for you.
When it comes to their generic alternatives:
- Norgestimate and ethinyl estradiol tablets (generic version of Sprintec) are available in packs of 28 with approximate costs ranging from $10-$20 for the entire pack - this translates into about $0.35 to $0.71 daily.
- For tri-lo-sprintec (the generic version of Ortho Tri Cyclen Lo), prices can range from about $30-$60 for a 28-tablet package or about $1 to$2 per day.
Despite being cheaper than their respective branded counterparts, it's crucial that you speak with your healthcare provider before making any changes as efficacy and side effects may vary among individuals using different brands or generics.
Popularity of Sprintec and Ortho Tri Cyclen Lo
Sprintec, a combined oral contraceptive pill that contains both an estrogen and progestin component, was prescribed to roughly 4.2 million people in the U.S. in 2020. Sprintec accounted for nearly 15% of combined oral contraceptive prescriptions in the country last year, making it one of the most commonly used birth control pills.
Ortho Tri-Cyclen Lo is another popular choice when it comes to contraceptives; approximately 3 million prescriptions were filled out for this drug within the same time frame. Ortho Tri-Cyclen Lo accounts for about 10% of all combination birth control pill prescriptions in the U.S., placing it among top choices as well but slightly behind Sprintec.
Both versions have been steady or increasing slightly in terms of prevalence over the past decade or so with minor fluctuations due to changes in health care policy and availability of other options such as long-acting reversible contraceptives (LARCs). But overall, these two medications remain cornerstones when considering hormonal contraception methods.
Conclusion
Both Sprintec (norgestimate and ethinyl estradiol) and Ortho Tri-Cyclen Lo (norgestimate/ethinyl estradiol) are well-established contraceptives with a long history of usage in preventing pregnancy. They have been shown to be more effective than placebo treatments, as reflected by numerous clinical studies. Both drugs contain the same active ingredients but at different doses, which may influence their effectiveness and side effects profile.
Ortho Tri-Cyclen Lo is often prescribed for its lower hormone dosage compared to Sprintec, making it a suitable choice for those who are sensitive to hormonal changes or wish to avoid common side effects associated with higher-dose contraceptive pills like weight gain or mood swings.
Sprintec is usually considered as an alternative option when patients do not respond well to first-line low-dose birth control pills or seek more robust menstrual cycle regulation provided by its higher hormone levels.
Both medications are available in generic form allowing significant cost savings especially for patients who must pay out of pocket. An adjustment period might be required before the full benefits become noticeable upon starting either medication.
The side effect profiles between these two contraceptives are similar; however, due to the differing dosages, some individuals may experience fewer hormonal-related side-effects on Ortho Tri-Cyclen Lo than on Sprintec. It's essential that users monitor their physical condition closely after beginning either treatment regimen and consult with healthcare professionals if they notice any adverse reactions.
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Refrences
- Hampton, R. M., Short, M., Bieber, E., Bouchard, C., Ayotte, N., Shangold, G., … Creasy, G. W. (2001, June). Comparison of a novel norgestimate/ethinyl estradiol oral contraceptive (Ortho Tri-Cyclen Lo) with the oral contraceptive Loestrin Fe 1/20. Contraception. Elsevier BV.http://doi.org/10.1016/s0010-7824(01)00214-1
- LaGuardia, K. D., Shangold, G., Fisher, A., Friedman, A., & Kafrissen, M. (2003, June). Efficacy, safety and cycle control of five oral contraceptive regimens containing norgestimate and ethinyl estradiol. Contraception. Elsevier BV.http://doi.org/10.1016/s0010-7824(03)00069-6
- LeBlanc, E. S., & Laws, A. (1999, October). Benefits and risks of third-generation oral contraceptives. Journal of General Internal Medicine. Springer Science and Business Media LLC.http://doi.org/10.1046/j.1525-1497.1999.08108.x
- Hampton, R. M., Short, M., Bieber, E., Bouchard, C., Ayotte, N., Shangold, G., … Creasy, G. W. (2001, June). Comparison of a novel norgestimate/ethinyl estradiol oral contraceptive (Ortho Tri-Cyclen Lo) with the oral contraceptive Loestrin Fe 1/20. Contraception. Elsevier BV.http://doi.org/10.1016/s0010-7824(01)00214-1