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HMG-CoA Reductase Inhibitor
Atorvastatin ± Aspirin for Lynch Syndrome
Recruiting1 awardPhase < 1
Philadelphia, Pennsylvania
This trial is testing whether a cholesterol-lowering drug (atorvastatin) alone or with a pain reliever (aspirin) can reduce colon cancer risk in people with Lynch syndrome. These individuals are at high risk for colon cancer. The study will look at how these drugs affect cell growth, death, and gene changes in the colon. Statins have anticancer activity in various cell types, including colon cancer cells.
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