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PI3K Inhibitor
Tipifarnib + Alpelisib for Head and Neck Cancer
Recruiting1 awardPhase 1 & 2
Orlando, Florida
This trial tests a combination of two drugs, tipifarnib and alpelisib, in patients with advanced head and neck cancer that have specific genetic changes. The drugs aim to stop cancer growth by blocking essential enzymes. Tipifarnib is a farnesyl transferase inhibitor that has shown clinical activity in head and neck squamous cell carcinoma, particularly in tumors with HRAS mutations.
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