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Histone Deacetylase Inhibitor
Belinostat/Pralatrexate + CHOP for T-Cell Lymphoma
Recruiting2 awardsPhase 3
Louisville, Kentucky
This trial is testing two new drugs, Belinostat and Pralatrexate, combined with standard chemotherapy in patients with newly diagnosed PTCL. The goal is to find the safest and most effective dose. The new drugs work by either blocking cancer cell growth or tricking cancer cells into absorbing a harmful substance. Pralatrexate is a specially designed drug with greater preclinical antitumor activity than methotrexate.
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