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Flavanols
Cocoa Flavanols for Peripheral Arterial Disease
Recruiting1 awardPhase 3
Chicago, Illinois
This trial will test whether cocoa flavanols can improve peripheral artery disease by measuring six-minute walk distance, Actigraph-measured physical activity, brachial artery flow-mediated dilation (FMD), gastrocnemius muscle biopsy measures of endothelial nitric oxide synthase (eNOS) and phosphorylated eNOS, gastrocnemius muscle perfusion (measured by magnetic resonance imaging (MRI)) and gastrocnemius muscle characteristics (measured by muscle biopsy).
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