Aristocort

Macular Edema, Stomatitis, Denture, Ophthalmia, Sympathetic + 113 more

Treatment

9 FDA approvals

20 Active Studies for Aristocort

Treatment for

Macular Edema

What is Aristocort

TriamcinoloneThe Generic name of this drug

Treatment SummaryTriamcinolone is a steroid used to treat various types of inflammation, from allergies to multiple sclerosis. It can be used as a one-time treatment for knee pain related to arthritis, or as a topical treatment for skin conditions. There are several forms of triamcinolone, including hexacetonide, acetonide, and diacetate. Triamcinolone was approved by the FDA in 1957, and in 2021 a suspension of triamcinolone acetonide was approved for suprachoroidal injection to treat macular edema associated with uveitis.

Aristocortis the brand name

image of different drug pills on a surface

Aristocort Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aristocort

Triamcinolone

1961

532

Approved as Treatment by the FDA

Triamcinolone, also called Aristocort, is approved by the FDA for 9 uses which include Keloids Scars and Ganglia .

Keloids Scars

Helps manage Keloids Scars

Ganglia

Helps manage cystic tumour of the ganglia

Lichen Planus

Helps manage Lichen Planus (LP)

Granuloma Annulare

Helps manage granuloma annulare lesions

Psoriasis

Helps manage Psoriatic plaque

Alopecia Areata

Helps manage Alopecia Areata (AA)

Neurodermatitis

Helps manage Lichen simplex chronicus

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

Necrobiosis lipoidica diabeticorum

Helps manage Necrobiosis lipoidica diabeticorum

Effectiveness

How Aristocort Affects PatientsTriamcinolone is a type of medication which reduces inflammation in many areas of the body. It should not be injected directly into the spine.

How Aristocort works in the bodyTriamcinolone helps reduce inflammation. It does this by limiting the breakdown of cell membranes which prevents the formation of certain acids. These acids are responsible for producing signals that cause inflammation. Triamcinolone also helps by making blood vessels less wide, and reducing the number of cells that flow to sites of inflammation.

When to interrupt dosage

The advised portion of Aristocort is contingent upon the determined condition, including Mycosis Fungoides (MF), Mycoses and Alopecia Areata (AA). The amount of dosage fluctuates as per the technique of delivery (e.g. Ointment or Injection, suspension - Intralesional; Parenteral) featured in the table beneath.

Condition

Dosage

Administration

Macular Edema

, 40.0 mg/mL, 10.0 mg/mL, 0.055 mg, 0.001 mg/mg, 0.25 mg/mL, 1.0 mg/mL, 0.0005 mg/mg, 0.00025 mg/mg, 0.005 mg/mg, 5.0 mg/mL, 20.0 mg/mL, 0.000147 mg/mg, 0.5 mg/mL, 40.0 mg, 1.0 mg, 0.000025 mg/mg, 0.1 %, 0.025 %, 5.0 mg, 0.25 mg, 2.0 mg, 4.0 mg, 0.5 %, 15.0 mg/mL, 6.5 mg, 80.0 mg/mL, 0.075 mg, 200.0 mg/mL, 32.0 mg, 0.055 mg/dose, 0.5 mg, 0.2 mg/pump actuation, 0.1 mg/dose, 25.0 mg/mL, 0.055 mg/pump actuation, 2.0 mg/mL, 0.4 mg/mL

Injection, suspension - Intra-articular; Intramuscular, Injection, suspension, Intra-articular; Intramuscular, , Intra-articular; Intralesional, Injection, suspension - Intra-articular; Intralesional, Nasal, Spray, metered, Spray, metered - Nasal, Topical, Cream, Cream - Topical, Ointment, Ointment - Topical, Lotion, Lotion - Topical, Intralesional; Parenteral, Injection, suspension - Intralesional; Parenteral, Intra-articular; Parenteral, Injection, suspension - Intra-articular; Parenteral, Intra-articular; Intrabursal; Intradermal; Intralesional, Injection, suspension - Intra-articular; Intrabursal; Intradermal; Intralesional, Aerosol, spray, Aerosol, spray - Topical, Paste, Paste - Topical, Kit, Injection, suspension - Intramuscular, Intramuscular, Dental, Paste - Dental, Suspension, Suspension - Intra-articular; Intramuscular, Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension - Intra-articular; Intrabursal; Intradermal; Intrasynovial, Intra-articular; Intrabursal; Intramuscular, Suspension - Intra-articular; Intrabursal; Intramuscular, Intralesional, Suspension - Intralesional, Aerosol, metered, Aerosol, metered - Nasal, Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Intra-articular, Suspension - Intra-articular, Oral, Tablet, Tablet - Oral, Liquid, Intra-articular; Intramuscular; Intrasynovial, Liquid - Intra-articular; Intramuscular; Intrasynovial, Syrup - Oral, Syrup, Intra-articular; Intradermal; Intramuscular, Liquid - Intra-articular; Intradermal; Intramuscular, Suspension - Intramuscular, Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intra-articular; Intradermal; Intralesional; Intramuscular, Spray, suspension - Nasal, Injection, solution, Injection, solution - Intra-articular; Intramuscular, Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Kit - Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Ophthalmic, Injection, suspension - Ophthalmic, Intravitreal, Suspension - Intravitreal, Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Kit - Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Spray, Spray - Topical, Intra-articular; Intrasynovial; Periarticular, Suspension - Intra-articular; Intrasynovial; Periarticular, Kit - Intra-articular; Intramuscular, Suspension - Ophthalmic, Subcutaneous, Implant, Implant - Subcutaneous, Epidural; Infiltration; Intra-articular; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intramuscular, Intra-articular; Intramuscular; Intravitreal, Injection, suspension - Intra-articular; Intramuscular; Intravitreal, Epidural; Intra-articular; Intramuscular; Topical, Kit - Epidural; Intra-articular; Intramuscular; Topical, Epidural; Infiltration; Intra-articular; Intralesional, Kit - Epidural; Infiltration; Intra-articular; Intralesional, Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Kit - Intra-articular, Paste, dentifrice, Paste, dentifrice - Dental, Kit - Infiltration; Soft tissue; Topical, Infiltration; Soft tissue; Topical, Ointment - Buccal, Buccal, Gel, Gel - Topical, Emulsion - Topical, Emulsion, Kit - Topical, Intra-articular; Intramuscular; Topical, Injection, suspension - Intra-articular, Infiltration; Intra-articular; Intramuscular; Topical, Kit - Infiltration; Intra-articular; Intramuscular; Topical

Ophthalmia, Sympathetic

Stomatitis, Aphthous

Multiple Sclerosis

Inflammation

Otitis Externa

Hypercalcemia

Hives

Berylliosis

Polymyositis

induction of Diuresis

Neurodermatitis

Intertrigo

Diaper Rash

Necrobiosis lipoidica diabeticorum

Pericarditis

Proteinuria

Tennis Elbow

Secondary adrenocortical insufficiency

Uveitis

Warnings

Aristocort has four contraindications. It should not be taken in case of any of the conditions found in the table below.Aristocort Contraindications

Condition

Risk Level

Notes

Mycoses

Do Not Combine

active periocular infections

Do Not Combine

Eye Infections

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Triamcinolone may interact with Pulse Frequency

There are 20 known major drug interactions with Aristocort.

Common Aristocort Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Triamcinolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Triamcinolone.

Aristocort Toxicity & Overdose RiskThe lowest toxic dose of triamcinolone acetonide for rats is 13,100µg/kg and 132mg/kg for mice. In rats, the lowest toxic dose is 1451mg/kg and 2168mg/kg in mice. When administered through the abdomen, the lowest toxic dose is 105mg/kg in mice. Those who overdose on triamcinolone acetonide may develop Cushing's syndrome, which can be treated with supportive therapy and mifepristone.

Aristocort Novel Uses: Which Conditions Have a Clinical Trial Featuring Aristocort?

Currently, 1076 active trials are examining the potential of Aristocort to provide relief from Lupus, Atopic Dermatitis and Brain Metastases.

Condition

Clinical Trials

Trial Phases

Asthma

97 Actively Recruiting

Phase 4, Not Applicable, Early Phase 1, Phase 2, Phase 3, Phase 1

Metastatic Brain Tumors

61 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4

Rheumatoid Arthritis

58 Actively Recruiting

Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1

Haemorrhoids

1 Actively Recruiting

Not Applicable

Congenital adrenal hyperplasia

8 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable

Granuloma Annulare

0 Actively Recruiting

oral lesions

0 Actively Recruiting

Communicable Diseases

0 Actively Recruiting

Craniotomy

0 Actively Recruiting

Inflammation

60 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3

Acne Vulgaris

0 Actively Recruiting

Lupus

63 Actively Recruiting

Phase 2, Phase 1, Phase 3, Not Applicable, Phase 4

Pure Red Cell Aplasia

1 Actively Recruiting

Phase 2

Lymphoma, Non-Hodgkin

3 Actively Recruiting

Phase 1

Eczema

0 Actively Recruiting

Pyoderma

8 Actively Recruiting

Phase 2, Phase 4, Early Phase 1, Phase 3, Not Applicable

Giant Cell Arteritis

7 Actively Recruiting

Phase 2, Phase 3, Phase 1

Itching of the Anus

0 Actively Recruiting

Ulcerative Colitis

12 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable

Rheumatic Heart Disease

0 Actively Recruiting

Aristocort Reviews: What are patients saying about Aristocort?

5Patient Review

1/17/2009

Aristocort for Rash

This treatment helps me a lot with my sweating and rashes. I'm really prone to getting pimples on my backside, but this cream takes care of it quickly.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aristocort

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for ARISTOCORT to work?

"This medication contains a topical anti-inflammatory drug from the corticosteroid family. It typically reduces inflammation and itching. Several days of treatment may be required to see the full effect."

Answered by AI

How does ARISTOCORT work in the body?

"Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here.

This medication is used to treat irritated skin, including conditions like psoriasis and eczema. It may also help with itchiness. The medication works by reducing swelling and inflammation of the skin. This medication is available in different forms and brand names. The specific brand may not be available for all the conditions discussed."

Answered by AI

Is ARISTOCORT a hydrocortisone?

"ARISTOCORT is a corticosteroid that comes in the form of a cream or ointment."

Answered by AI

What is ARISTOCORT cream used for?

"This medication is used to reduce the swelling, itching, and redness that can occur in a variety of skin conditions, such as eczema, dermatitis, allergies, and rash. It is a medium- to strong-potency corticosteroid."

Answered by AI

Clinical Trials for Aristocort

Image of Crinetics Study Site in Morehead City, United States.

Have you considered Aristocort clinical trials? We made a collection of clinical trials featuring Aristocort, we think they might fit your search criteria.

Image of University of Chicago in Chicago, United States.

Therapy De-escalation for Ulcerative Colitis

18 - 75

All Sexes

Chicago, IL

This trial aims to understand how to best treat people with ulcerative colitis. They will compare patients who are in remission and continue their medication to those who decrease or stop their medication. The goal

Waitlist Available

Has No Placebo

University of ChicagoDavid T Rubin, MD

Image of Helix Biomedics, LLC Site Number : 8400005 in Boynton Beach, United States.

Lunsekimig for Asthma

18 - 80

All Sexes

Boynton Beach, FL

This trial is testing a new medication called SC lunsekimig as an add-on therapy for asthma treatment. It will involve male and female participants with asthma who are not eligible for other biologic treatments

Phase 2

Recruiting

Drug

Helix Biomedics, LLC Site Number : 8400005 (+6 Sites)Sanofi

Image of InnovaDerm in Montreal, Canada.

PF-07905428 for Acne

18 - 40

All Sexes

Montreal, Canada

This trial aims to test a new medicine (PF-07905428) for treating acne vulgaris. They are looking for participants aged 18-40 with moderate to severe acne. The medicine will

Phase 1

Waitlist Available

Paid Trial

InnovaDermPfizer CT.gov Call CenterPfizer

Image of Altoona Center for Clinical Research in Duncansville, United States.

AP1189 + Methotrexate for Rheumatoid Arthritis

18+

All Sexes

Duncansville, PA

This trial is testing a new drug called AP1189 in combination with methotrexate for people with early rheumatoid arthritis. Participants will be given different doses of AP1189 for 12

Phase 2

Recruiting

Drug

Altoona Center for Clinical ResearchNBCD A/S

Have you considered Aristocort clinical trials? We made a collection of clinical trials featuring Aristocort, we think they might fit your search criteria.

Image of Salus Research in Fort Wayne, United States.

Stannous Fluoride Toothpaste + CPC Mouthwash for Gum Disease

18+

All Sexes

Fort Wayne, IN

"This trial aims to see if using a specific mouthwash and toothpaste together can improve gum health and reduce plaque better than just using a regular toothpaste in people with gum disease caused by plaque."

Recruiting

Has No Placebo

Salus ResearchHALEON

Image of University of Vermont Medical Center in Burlington, United States.

Exercise Program for Asthma

18+

All Sexes

Burlington, VT

This trial will study the use of a remote digital exercise program called Vitala in adults with obesity and poorly controlled asthma. The main goal is to see if participants find the program feasible and acceptable by completing

Waitlist Available

Has No Placebo

University of Vermont Medical Center

Image of The University of Texas MD Anderson Cancer Center in Houston, United States.

Systemic Therapy + Stereotactic Radiosurgery for Brain Cancer

18+

All Sexes

Houston, TX

This trial aims to determine if using stereotactic radiosurgery (SRS) can help manage brain metastases in patients who have not fully responded to systemic therapy. It also seeks to compare the effectiveness

Phase 2

Waitlist Available

Has No Placebo

The University of Texas MD Anderson Cancer CenterThomas H Beckham, MD,PHD

Image of Mayo Clinic Florida in Jacksonville, United States.

Virtual Reality for Abdominal Pain in Crohn's Disease

18 - 70

All Sexes

Jacksonville, FL

This trial aims to determine if patients with Crohn's disease who experience abdominal pain and reduced quality of life, even without active inflammation, can benefit from using virtual reality technology.

Recruiting

Has No Placebo

Mayo Clinic FloridaJami Kinnucan, MD

Have you considered Aristocort clinical trials? We made a collection of clinical trials featuring Aristocort, we think they might fit your search criteria.