Moxatag

Urinary Tract Infections, Sinusitis, Gonorrhea + 11 more

Treatment

2 FDA approvals

20 Active Studies for Moxatag

Treatment for

Urinary Tract Infections

What is Moxatag

Amoxicillin

The Generic name of this drug

Treatment Summary

Amoxicillin, also known as BRL-2333, is a type of penicillin medication that was first discovered in 1972. It is similar to other penicillin medications, but it can produce higher levels of the drug in the bloodstream than ampicillin. Amoxicillin was approved by the FDA in 1974.

Amoxicillin

is the brand name

image of different drug pills on a surface

Moxatag Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Amoxicillin

1978

1067

Approved as Treatment by the FDA

Amoxicillin, also called Amoxicillin, is approved by the FDA for 2 uses including Duodenal Ulcer and Duodenal ulcer caused by helicobacter pylori .

Duodenal Ulcer

Used to treat Duodenal ulcer caused by helicobacter pylori in combination with Clarithromycin

Duodenal ulcer caused by helicobacter pylori

Used to treat Duodenal ulcer caused by helicobacter pylori in combination with Clarithromycin

Effectiveness

How Moxatag Affects Patients

Amoxicillin works by blocking certain proteins that are necessary for the growth of bacteria, which prevents them from multiplying. It is usually prescribed to be taken twice per day, and it is generally safe even if taken in slightly larger amounts than prescribed. Patients should be aware of the potential risks of anaphylaxis, severe stomach infections, and developing resistance to the drug.

How Moxatag works in the body

Amoxicillin works by stopping a particular type of protein from being able to bind with molecules in bacterial cell walls. Without this protein, the bacteria cannot construct or repair their cell walls and will eventually die.

When to interrupt dosage

The measure of Moxatag is contingent upon the recognized affliction, including Lower Respiratory Tract Infection (LRTI), Duodenal Ulcer and Stomach Ulcer. The quantity of dosage can be found in the table below, contingent upon the technique of delivery (e.g. For suspension - Oral or Oral).

Condition

Dosage

Administration

ear, nose, and throat infections

, 500.0 mg, 875.0 mg, 200.0 mg, 400.0 mg, 200.0 mg/mL, 400.0 mg/mL, 600.0 mg/mL, 250.0 mg, 125.0 mg/mL, 250.0 mg/mL, 125.0 mg, 775.0 mg, 1000.0 mg, 25.0 mg/mL, 50.0 mg/mL, 600.0 mg, 437.5 mg, 2000.0 mg

, Oral, Tablet, film coated, Tablet, film coated - Oral, Powder, for suspension, Powder, for suspension - Oral, Tablet, chewable, Tablet, chewable - Oral, Kit, Suspension - Oral, Capsule, Capsule - Oral, Suspension, Tablet, coated, Tablet, coated - Oral, Tablet - Oral, Tablet, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, For suspension, For suspension - Oral, Granule, for suspension, Granule, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Capsule; Capsule, delayed release; Kit; Tablet, Capsule; Capsule, delayed release; Kit; Tablet - Oral, Tablet, soluble, Tablet, soluble - Oral, Tablet, for suspension - Oral, Tablet, for suspension, Tablet, extended release - Oral, Tablet, extended release, Kit - Oral, Intravenous, Powder, for solution - Intravenous, Capsule, delayed release, Capsule, delayed release - Oral

Gonorrhea

Sinusitis

Bronchitis

Otitis

ABDIC protocol

Duodenal Ulcer

Bacterial Infections

Urinary Tract Infection (UTI)

Peptic Ulcer With H. Pylori Infection

Community Acquired Pneumonia (CAP)

Urinary Tract Infections

Helicobacter Pylori Infection

Warnings

Moxatag Contraindications

Condition

Risk Level

Notes

Liver Dysfunction

Do Not Combine

Pulse Frequency

Do Not Combine

Jaundice, Obstructive

Do Not Combine

Jaundice, Obstructive

Do Not Combine

Liver Dysfunction

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Amoxicillin may interact with Pulse Frequency

There are 20 known major drug interactions with Moxatag.

Common Moxatag Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Amoxicillin.

Aclidinium

Minor

Amoxicillin may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Amoxicillin may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Albutrepenonacog alfa

Minor

Amoxicillin may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.

Allylestrenol

Minor

Amoxicillin may decrease the excretion rate of Allylestrenol which could result in a higher serum level.

Moxatag Toxicity & Overdose Risk

An overdose on ibuprofen could lead to bloody urine, decreased urine production, stomach pain, kidney failure, vomiting, diarrhea, rash, excessive energy, and drowsiness. To treat an overdose, doctors may recommend vomiting or dialysis, as well as providing supportive care.

image of a doctor in a lab doing drug, clinical research

Moxatag Novel Uses: Which Conditions Have a Clinical Trial Featuring Moxatag?

Currently, 60 active studies are underway to assess the utility of Moxatag in treating Urinary Tract Infection, Otolaryngological Infections and Bacterial Pathologies.

Condition

Clinical Trials

Trial Phases

Bacterial Infections

0 Actively Recruiting

Urinary Tract Infections

0 Actively Recruiting

Duodenal Ulcer

0 Actively Recruiting

Bronchitis

2 Actively Recruiting

Not Applicable

ABDIC protocol

0 Actively Recruiting

ear, nose, and throat infections

0 Actively Recruiting

Community Acquired Pneumonia (CAP)

5 Actively Recruiting

Not Applicable, Phase 1, Phase 3

Sinusitis

2 Actively Recruiting

Not Applicable

Helicobacter Pylori Infection

2 Actively Recruiting

Not Applicable, Phase 4

Peptic Ulcer With H. Pylori Infection

0 Actively Recruiting

Urinary Tract Infections

7 Actively Recruiting

Not Applicable, Phase 4

Gonorrhea

0 Actively Recruiting

Urinary Tract Infection (UTI)

6 Actively Recruiting

Phase 1, Phase 3, Phase 4, Phase 2

Otitis

3 Actively Recruiting

Not Applicable

Moxatag Reviews: What are patients saying about Moxatag?

Patient Review

12/7/2009

Moxatag for Strep Throat

This medication was a life-saver. I had severe strep and couldn't eat or drink for two days. After taking Moxatag, I felt better the next day. On day four, I feel 90% better.

Patient Review

4/23/2009

Moxatag for Strep Throat

4.7

Patient Review

11/4/2009

Moxatag for Strep Throat and Tonsillitis

I was really surprised by how quickly this drug kicked in and relieved my throat pain. I did have some stomach pain afterwards, but it was worth it to get rid of the infection.

4.7

Patient Review

8/27/2009

Moxatag for Strep Throat and Tonsillitis

Moxatag is much easier to take than other strep treatments, since you only have to do it once a day. Even though it's a bit more expensive, I think the convenience is worth it.

4.3

Patient Review

8/2/2011

Moxatag for Strep Throat

I'm five days in with no relief yet, but I'll give it a few more days. The only downside is the headaches I've been getting; thankfully Advil takes care of that pain.

4.3

Patient Review

2/7/2010

Moxatag for Strep Throat

This medication is very effective; however, I get terrible headaches as a side effect.

4.3

Patient Review

4/24/2011

Moxatag for Strep Throat and Tonsillitis

I'm on day seven and I've finally started to feel some relief.

3.7

Patient Review

3/16/2010

Moxatag for Strep Throat

After four days of a throbbing, scratchy throat, I went to my doctor. He prescribed Moxatag 775. After taking the first pill, I didn't feel any better and actually had some adverse reactions like dry mouth and restless sleep. However, 24 hours after taking the second pill, I'm feeling much better--no more coughing fits and less general discomfort. I'll wait until I finish the entire course of medication before giving my final verdict on its effectiveness.

Patient Review

2/5/2011

Moxatag for Strep Throat

I've been struggling with a sore throat for four days now, and I'm only on day two of this treatment. So far, I haven't experienced any relief. My doctor told me that I should have felt the effects by now, but unfortunately that hasn't been the case. The first night was spent tossing and turning in pain; however, if I regularly swallowed it did help to ease the pain somewhat. He gave me ten pills in total, saying that by day three I would be feeling better. Let's hope so. All things considered, while this medication may work eventually, don't expect any fast results.

2.7

Patient Review

3/11/2010

Moxatag for Strep Throat

I have had Strep throat for 4 days now and have been taking Moxatag. I was told by my doctor that I would feel relief in a day or 2, but unfortunately I have not experienced any change. Tylenol seems to be the only thing helping with the pain and fever at this point.

2.3

Patient Review

11/19/2009

Moxatag for Strep Throat

My son is still in a lot of pain from his strep throat despite starting this medication. We were told it would work within 24 hours, but it's now been 36 and there's no change. Fingers crossed that it will start working soon.

2.3

Patient Review

1/12/2010

Moxatag for Strep Throat

Even after taking two pills, I'm still waiting for relief from this awful sore throat. So far, no luck.

1.7

Patient Review

1/9/2010

Moxatag for Strep Throat and Tonsillitis

I wasn't a big fan of this treatment because it took forever to work.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about moxatag

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for moxatag?

"It will not work for viral infections (such as common cold, flu).

Amoxicillin is used to treat a wide variety of bacterial infections. This medication is a penicillin-type antibiotic and works by stopping the growth of bacteria. However, this antibiotic will not work against viral infections such as the common cold or the flu."

Answered by AI

What is the generic name of amoxicillin?

"The Amoxicillin drug is available as a cheaper generic version, which is just as effective as the more expensive branded version. In most cases, the generic medication will be a more cost-effective option."

Answered by AI

What is amoxicillin used to treat?

"Amoxicillin is most commonly used to treat chest and dental infections, as well as stomach ulcers. It is also frequently prescribed for children to treat ear infections and other chest infections."

Answered by AI

What is moxatag used for?

"Moxatag is a prescription medicine used to treat the symptoms of various infections like tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract. Moxatag may be used alone or with other medications. Moxatag belongs to a class of drugs called Penicillins, Amino."

Answered by AI

Clinical Trials for Moxatag

Image of Children's of Alabama in Birmingham, United States.

Antibiotic Duration for Infections in Children

60 - 17

All Sexes

Birmingham, AL

Infections like pneumonia, skin and soft tissue infection (also called SSTI or cellulitis), and urinary tract infections (UTI) are some of the most common reasons children get admitted to the hospital. All three of these conditions require antibiotics for treatment. Although antibiotics are needed to treat the infection and help children feel better, taking them longer than needed can negatively impact children and their families. Negative impacts include things like the burdens of taking more medications and medication side effects. There are guidelines (instructions) from expert medical organizations that suggest the number of days children need antibiotics, but they give a wide range (between 5 and 14 days). Unfortunately, these guidelines are not based on high-quality studies. National data suggests that doctors often choose on the higher end of this range when writing prescriptions for children in the hospital. Our three caregiver co-investigators, other parents of hospitalized children, doctors, other care providers, and researchers, all believe that additional study is needed to determine the best length of antibiotic treatment that weighs both the benefits and harms of antibiotics. The goal of our study is to understand if 5 total days of antibiotic treatment compared to 10 total days of antibiotic treatment is better for children who have been in the hospital for pneumonia, SSTI, or UTI. We will study this question through a randomized control trial. In other words, half of the children will receive 5-days of antibiotics and the other half will receive 10-days of antibiotics. Children in this study (and their caregivers) will not know how many days of antibiotics they will receive to cure their infection because some children will take a placebo (or a pill without antibiotics in it). Only the pharmacy will know if a child is getting antibiotic or placebo (for days 6-10 of treatment). During the first phase of the trial (feasibility phase), 4 hospitals will enroll children in the study. We plan on enrolling 50 patients during this phase. We are starting with just 4 hospitals, so our study team can create and update our study plans if needed. We will closely review information about how many patients and families agree to participate, and if they have any trouble completing any part of the study. We will also interview families to understand the choice to participate in the study, the choice not to participate in the study, and what it is like to be in the study. During the second study phase, we will enroll 1150 more patients across all 11 hospitals. Families will complete short, daily surveys until the 15th day after they started antibiotics, then a larger survey at day 15, at day 20, and at day 30. These surveys will ask about the child's symptoms and recovery from their illness, how the antibiotics are making them feel, and if they had to go back to their doctor, emergency room, or hospital. The answers to these questions will be combined to measure how well the child did, balancing feeling better and having bad effects from the antibiotics. We will use mathematical tests to determine which antibiotic duration is better for treating these illnesses. We will complete other mathematical tests to see if all children should receive the same length of antibiotics or if certain children should be prescribed shorter courses and others longer courses.

Phase 4

Waitlist Available

Drug

Children's of Alabama (+9 Sites)

Sunitha V Kaiser, MD, MSc

Image of Baylor College of Medicine in Houston, United States.

Educational Tool for Urinary Tract Infections

18+

All Sexes

Houston, TX

Urine culture is the most common microbiological test in the outpatient setting in the United States. Unfortunately, contamination during collection is prevalent and undermines test accuracy, leading to incorrect diagnosis, unnecessary treatment, wasted laboratory resources, and inflated costs. Unnecessary antibiotic treatment increases the risk of developing antimicrobial resistance, one of the most serious threats to patients and public health. The goal of this clinical trial is to test whether a bilingual (English and Spanish) educational intervention, an animated video and pictorial flyer, can reduce urine culture contamination and associated inappropriate antibiotic use in adult patients visiting safety-net primary care clinics. The main questions it aims to answer are: 1. Does providing patients with a bilingual educational intervention reduce urine culture contamination rates? 2. Does the intervention lead to fewer unnecessary urinary antibiotic prescriptions? 3. Does providing patients with a bilingual educational intervention reduce contaminated urinalyses? Researchers will compare patients randomized to receive the educational intervention (video and flyer) to those receiving usual care to see if the intervention improves urine collection accuracy and reduces inappropriate antibiotic use. Participants will watch a short, animated video with step-by-step instructions for proper midstream clean-catch urine (MSCC) collection, receive a pictorial flyer (with stills from the video) reinforcing the instructions, and provide a urine sample for culture. Hypothesis: patients who receive the educational intervention will have: lower urine culture contamination rates (primary outcome), fewer urinary antibiotic prescriptions (secondary outcome), and fewer contaminated urinalyses (secondary outcome). The objectives are to (1) develop educational tools: Create an animated video and pictorial flyer with step-by-step urine collection instructions for women and men, developed through an iterative, stakeholder-engaged process, (2) assess acceptability: Use mixed methods (quantitative surveys and qualitative interviews) to evaluate and refine the tools for usability and cultural/linguistic appropriateness, and (3) test effectiveness: Conduct a randomized controlled trial to assess the intervention's impact on urine contamination rates, antibiotic prescribing, and patient satisfaction.

Waitlist Available

Has No Placebo

Baylor College of Medicine

Larissa Grigoryan, MD, PhD