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What is Risperdal
RisperidoneThe Generic name of this drug
Treatment SummaryRisperidone is a medication used to treat mental health conditions like schizophrenia and bipolar disorder. It is a type of antipsychotic medication that works by blocking certain chemical receptors in the brain, reducing the overactivity of certain pathways. Risperidone binds very strongly to certain receptors in the brain, and has lesser activity at other targets which may contribute to side effects.
Risperidoneis the brand name
Risperdal Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Risperidone
Risperidone
1993
522
Approved as Treatment by the FDA
Risperidone, also known as Risperidone, is approved by the FDA for 6 uses such as Mixed manic depressive episode and Bipolar 1 Disorder .Mixed manic depressive episode
Bipolar 1 Disorder
Acute Mania
Common Cold
Bipolar Disorder
Bipolar Disorder
Effectiveness
How Risperdal Affects PatientsRisperidone works by reducing the activity of certain chemicals in the brain like dopamine and serotonin. It does this by attaching itself to certain receptors in the brain, with a higher binding affinity for serotonin receptors than dopamine receptors. This makes it different from other antipsychotic drugs which tend to attach more strongly to dopamine receptors. This difference is thought to be the reason why risperidone causes fewer side effects than its predecessors.
How Risperdal works in the bodyRisperidone works by stopping too much dopamine and serotonin from being released in the brain. Excess dopamine and serotonin can cause delusions, hallucinations and other symptoms of schizophrenia. Risperidone is able to block these receptors for a short time, reducing the amount of dopamine and serotonin in the brain. This helps to reduce the symptoms of schizophrenia without causing side effects. Risperidone also blocks other receptors such as alpha-1, alpha-2, and histamine, which may also help reduce symptoms of schizophrenia, though the exact mechanism of action is not yet known.
When to interrupt dosage
The measure of Risperdal is contingent upon the determined issue, including Psychotic Disorders, Irritability and Acute Mania. The quantity of dosage changes, as per the procedure of delivery (e.g. Subcutaneous or Solution) presented in the table below.Condition
Dosage
Administration
Autism
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Acute Coryza
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Bipolar Disorder
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Behcet Syndrome
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Alzheimer's Disease
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Common Cold
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
responsive to first treatment
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Irritability
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Psychotic Disorders
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Bipolar Disorder
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Warnings
Risperdal has two contraindications. It should not be taken when encountering any of the conditions listed in the following table.Risperdal ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Risperidone may interact with Pulse Frequency
Common Risperdal Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Risperidone may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Risperidone may increase the antipsychotic activities of Amisulpride.
Aripiprazole
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Risperdal Toxicity & Overdose RiskOverdosing on Levetiracetam can cause fatigue, body spasms, rapid heart rate, slow heart rate, and seizures. The lethal dose in rats is 57.7 mg/kg if given orally or 34 mg/kg if given intravenously.
Risperdal Novel Uses: Which Conditions Have a Clinical Trial Featuring Risperdal?
359 active studies are currently being conducted to evaluate the potential of Risperdal to provide relief from Acute Mania, Bipolar Disorder and Autism.Condition
Clinical Trials
Trial Phases
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Behcet Syndrome
2 Actively Recruiting
Not Applicable, Phase 1
Schizophrenia
108 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Schizophrenia
0 Actively Recruiting
Bipolar Disorder
0 Actively Recruiting
Irritability
7 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1
Psychotic Disorders
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Common Cold
0 Actively Recruiting
Autism
6 Actively Recruiting
Phase 2, Not Applicable
Bipolar Disorder
0 Actively Recruiting
Alzheimer's Disease
27 Actively Recruiting
Not Applicable, Phase 2, Phase 1
responsive to first treatment
0 Actively Recruiting
Risperdal Reviews: What are patients saying about Risperdal?
4Patient Review
2/13/2022 I definitely notice a difference in my mood stability when I'm on this medication. Without it, I tend to swing to more extreme emotions; however, while on the medication, I feel much more even-keeled.
4Patient Review
8/13/2022 It can be tough to keep my eyes open on this medication, but I've gotten used to it. The only other downside is that sidewalk walking and being around cars can be dangerous if my eyes close for even a few seconds. But overall, this med works great for my schizophrenia.
4Patient Review
9/4/2019 I felt a little dizzy on the first day taking risperidone, but that went away quickly. After a month of taking it, I've noticed my focus and concentration have improved significantly. The only downside is that I feel a little tired, but it's not too bad.
4Patient Review
8/13/2022 It can be tough to keep my eyes open when I'm on this medication, but I've gotten used to it. The main thing is that it really helps with my schizophrenia.
4Patient Review
9/4/2019 I felt a little dizzy after taking the medication the first day, but that went away. I've been on it for 4 weeks now and have definitely noticed an improvement in my focus and concentration. The medicine makes me feel a little tired, but it's not too bad.
Patient Q&A Section about risperdal
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the side effect of Risperdal?
"To minimize dizziness and lightheadedness, get up slowly from a sitting or lying position.
Drowsiness, dizziness, lightheadedness, drooling, nausea, weight gain, or tiredness may occur. These effects can persist or worsen- tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling, so get up slowly when rising from a sitting or lying position."
Answered by AI
What is the drug Risperdal used for?
"This medication is used to treat conditions such asschizophrenia, bipolar disorder, or autism-related irritability. It is not to be used for behavioral issues in adults with dementia. A prescription from a doctor is required to obtain this medication."
Answered by AI
Is Risperdal a Xanax?
"Risperdal is usually given to people with schizophrenia, bipolar mania, and autism. Xanax is mostly given to people who have panic attacks and anxiety disorders. Risperdal and Xanax work differently and are not in the same drug class."
Answered by AI
How does Risperdal make you feel?
"It can take several days or even months for risperidone to work. Common side effects include feeling sleepy, problems with your movement and headaches. You may also feel more hungry than usual, which can lead to weight gain."
Answered by AI