Tri-Previfem

Acne Vulgaris, moderate Vulvovaginal atrophy, Hot flashes + 9 more
Treatment
8 FDA approvals
20 Active Studies for Tri-Previfem

What is Tri-Previfem

NorgestimateThe Generic name of this drug
Treatment SummaryEthinylestradiol was developed in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at the Schering company. It was created to be a more effective form of estrogen with higher availability when taken orally. Ethinylestradiol is now used in many contraceptive pills and was approved by the FDA in 1943.
Ortho Tri Cyclenis the brand name
image of different drug pills on a surface
Tri-Previfem Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ortho Tri Cyclen
Norgestimate
1989
113

Approved as Treatment by the FDA

Norgestimate, commonly known as Ortho Tri Cyclen, is approved by the FDA for 8 uses which include Oral Contraceptives and Osteoporosis, Postmenopausal .
Oral Contraceptives
Used to treat Oral Contraceptives in combination with Ethinylestradiol
Osteoporosis, Postmenopausal
Used to treat Postmenopausal Osteoporosis in combination with Estradiol
Acne Vulgaris
Used to treat moderate Acne vulgaris in combination with Ethinylestradiol
moderate Vulvovaginal atrophy
Used to treat moderate Vulvovaginal atrophy in combination with Estradiol
Hot flashes
Used to treat Menopause in combination with Estradiol
moderate Menopausal Vasomotor Symptoms
Used to treat moderate Menopausal Vasomotor Symptoms in combination with Estradiol
Menopause
Used to treat severe Vasomotor Symptoms Associated With Menopause in combination with Estradiol
severe menopausal vulvovaginal atrophy
Used to treat severe menopausal vulvovaginal atrophy in combination with Estradiol

Effectiveness

How Tri-Previfem Affects PatientsEthinylestradiol is a synthetic version of the hormone estrogen. It helps reduce luteinizing hormone and gonadotrophic hormone levels in the body, which can reduce the growth of the lining of the womb and prevent ovulation. It is taken once a day and is considered to be a relatively safe drug, though patients should be aware of the risk of blood clotting.
How Tri-Previfem works in the bodyEthinylestradiol is a synthetic hormone that is used in combined oral contraceptives. It works by blocking the hormones that cause ovulation, making it harder for sperm to travel, and preventing changes in the uterus that allow for pregnancy. It also decreases luteinizing hormone levels, which lowers the amount of blood flow to the uterus. Lastly, it increases the amount of a protein (sex hormone binding globulin) that binds to hormones and stops them from working.

When to interrupt dosage

The measure of Tri-Previfem is contingent upon the diagnosed condition, including Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The quantity of dosage fluctuates as per the technique of delivery as outlined in the table beneath.
Condition
Dosage
Administration
Polycystic Ovarian Syndrome
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menopause
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
severe menopausal vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Osteoporosis, Postmenopausal
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Oral Contraceptives
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menorrhagia
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hirsutism
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Menopausal Vasomotor Symptoms
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hot flashes
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Acne Vulgaris
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Dysmenorrhea
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral

Warnings

Tri-Previfem has twenty-six contraindications and should not be consumed by those experiencing any of the conditions in the following table.Tri-Previfem Contraindications
Condition
Risk Level
Notes
Breast
Do Not Combine
Breast Cancer
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hypersensitivity
Do Not Combine
Venous Thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Metrorrhagia
Do Not Combine
Liver Neoplasms
Do Not Combine
There are 20 known major drug interactions with Tri-Previfem.
Common Tri-Previfem Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Norgestimate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Norgestimate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Norgestimate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Norgestimate.
Astemizole
Major
The metabolism of Astemizole can be increased when combined with Norgestimate.
Tri-Previfem Toxicity & Overdose RiskWomen who overdose on birth control may have symptoms such as bleeding, nausea, vomiting, breast tenderness, abdominal pain, drowsiness, and fatigue. Treatment for this should include monitoring potassium and sodium levels in the body, as well as signs of acidosis, and providing supportive care.
image of a doctor in a lab doing drug, clinical research

Tri-Previfem Novel Uses: Which Conditions Have a Clinical Trial Featuring Tri-Previfem?

38 active studies are currently assessing the potential of Tri-Previfem to provide Folate supplementation therapy, alleviate Premenstrual Dysphoric Disorder and manage Menopause-related symptoms.
Condition
Clinical Trials
Trial Phases
Dysmenorrhea
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Osteoporosis, Postmenopausal
0 Actively Recruiting
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Menopause
0 Actively Recruiting
Polycystic Ovarian Syndrome
8 Actively Recruiting
Not Applicable, Early Phase 1, Phase 4, Phase 1
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
Hirsutism
0 Actively Recruiting
Hot flashes
13 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Early Phase 1
moderate Vulvovaginal atrophy
0 Actively Recruiting
Menorrhagia
0 Actively Recruiting
severe menopausal vulvovaginal atrophy
0 Actively Recruiting

Tri-Previfem Reviews: What are patients saying about Tri-Previfem?

5Patient Review
2/25/2016
Tri-Previfem for Birth Control
This birth control has been my saving grace. I was on other pills before that gave me cramps, made my period irregular, and left me feeling emotionally out of balance; none of those problems exist now.
5Patient Review
8/24/2017
Tri-Previfem for Birth Control
I've been using this birth control for four years now, and it's never let me down. It cleared up my acne, made my boobs grow, and I haven't had any problems with it.
5Patient Review
5/2/2018
Tri-Previfem for Abnormal Bleeding from the Uterus
I can't speak highly enough of this medication for girls who have painful or long periods. This has been an absolute lifesaver for me and I haven't had to go to the ER once since starting it.
4.3Patient Review
5/4/2020
Tri-Previfem for Acne
I've been on the pill for a few months now, and it's done wonders for my acne. My skin is completely clear, and I haven't had a pimple in weeks. However, I have gained some weight and my breasts have gotten slightly bigger, which isn't ideal. I'm really stressed about the weight gain because I never had issues with my weight before.
4Patient Review
3/21/2016
Tri-Previfem for Birth Control
This treatment was effective in preventing pregnancy, but it came with some serious side effects. I became an emotional wreck, crying at everything and getting extremely moody. My stomach pains were horrible, and the headaches were constant. I would not recommend this to anyone unless you are prepared to deal with some very unpleasant symptoms.
3.7Patient Review
2/15/2019
Tri-Previfem for Acne
I've been taking this for two months now. I came from Loryana in hopes of finding something more effective for my acne, and so far this has done wonders for clearing up my skin. The only downside is that I feel like I'm gaining weight and my stomach always looks bloated.
3.3Patient Review
11/7/2021
Tri-Previfem for Premenstrual Disorder with a State of Unhappiness
Though this pill did prevent pregnancy, I gained weight and experienced changes in mood that left me feeling very unhappy.
3Patient Review
12/30/2016
Tri-Previfem for Birth Control
I've found that the other commentators are accurate in their assessment of this treatment. It gives you headaches, your boobs grow but are incredibly tender for months, and you become moody and irritable. My boyfriend thinks I should stop taking it, but other research shows that the alternative treatments can cause cancer to activate and be 10 times worse. So hopefully I'll get less bitchy and psycho when I reach my one year mark. Good luck!
1.7Patient Review
3/14/2019
Tri-Previfem for Premenstrual Disorder with a State of Unhappiness
I had a really bad experience with this medicine. I was shaking all over, couldn't grab my cup, and couldn't sleep. I also had sharp abdominal pain and mood swings.
1Patient Review
1/29/2019
Tri-Previfem for Birth Control
Do not under any circumstances take this pill. It caused me severe anxiety and panic attacks for no reason, abdominal pain, diarrhea, weight gain, burning skin, and rashes all over my body.
1Patient Review
5/23/2016
Tri-Previfem for Birth Control
This pill was a complete disaster for me. Not only did it fail to prevent pregnancy, but it also caused me to gain 30lbs, go from a DD to an H cup, and suffer from panic attacks and depression. On top of all that, the physical changes it made to my body (and my voice) practically ruined my singing career. Thank you Tri Previfem, for ruining my life!
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about tri-previfem

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of birth control is tri-Previfem?

"This pill contains a combination of progestin and estrogen which prevents pregnancy by making your body think it is already pregnant."

Answered by AI

What is the generic name for Tri-Previfem?

"Ortho Tri-Cyclen Lo is a birth control pill that is taken once a day, at the same time every day, for 21 days straight. Then, one dark green pill is taken daily for 7 days."

Answered by AI

Is Tri-Previfem the same as Tri Sprintec?

"There are several generic brands of Tri-Sprintec that are quite affordable if you choose to pay out-of-pocket. These include Trinessa, Tri-Estarylla, Tri-Previfem, Tri Norgestimate ethinyl estradiol or Tri-Linyah."

Answered by AI

Is Tri-Previfem still available?

"is the most recent update on this drug. Ortho Cyclen has been discontinued and if there are any generic equivalents, they will be available."

Answered by AI

Clinical Trials for Tri-Previfem

Have you considered Tri-Previfem clinical trials? We made a collection of clinical trials featuring Tri-Previfem, we think they might fit your search criteria.
Have you considered Tri-Previfem clinical trials? We made a collection of clinical trials featuring Tri-Previfem, we think they might fit your search criteria.
Image of University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research Laboratory in Aurora, United States.

MitoQ + Exercise for Menopause-Related Vascular Health

50 - 120
Female
Aurora, CO
This trial tests whether combining moderate aerobic exercise with the antioxidant MitoQ can improve blood vessel function in postmenopausal women who lack estrogen. MitoQ aims to reduce oxidative stress and enhance blood flow by improving mitochondrial function. The study will compare the effects of exercise with MitoQ, exercise alone, and MitoQ alone. MitoQ is a mitochondria-targeted antioxidant that has been studied for its potential to enhance exercise-induced muscle adaptations and improve peak power in untrained middle-aged men.
Phase < 1
Waitlist Available
University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research LaboratoryKerrie L Moreau, PhD
Have you considered Tri-Previfem clinical trials? We made a collection of clinical trials featuring Tri-Previfem, we think they might fit your search criteria.
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