Vasotec

Ventricular Dysfunction, Left, Diabetic Nephropathies, Hypertensive disease + 2 more

Treatment

5 FDA approvals

20 Active Studies for Vasotec

Treatment for

Ventricular Dysfunction, Left

What is Vasotec

EnalaprilThe Generic name of this drug

Treatment SummaryEnalapril is a drug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class and is used to regulate blood pressure and maintain balance of fluids and electrolytes in the body. The drug works by blocking the production of angiotensin II, a hormone that narrows blood vessels and increases sodium reabsorption. Enalapril is sold under the brand name Vasotec and was approved by the FDA in 1985 for the treatment of hypertension, heart failure, and asymptomatic left ventricular dysfunction. It can also be found in combination with hydrochlorothiazide for the treatment of

Vasotecis the brand name

image of different drug pills on a surface

Vasotec Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Vasotec

Enalapril

1985

352

Approved as Treatment by the FDA

Enalapril, also known as Vasotec, is approved by the FDA for 5 uses including Symptomatic Congestive Heart Failure and asymptomatic Left ventricular dysfunction .

Symptomatic Congestive Heart Failure

Helps manage Symptomatic Congestive Heart Failure

asymptomatic Left ventricular dysfunction

Helps manage asymptomatic Left ventricular dysfunction

Heart Failure

Helps manage Symptomatic Congestive Heart Failure

Hypertensive disease

Helps manage High Blood Pressure (Hypertension)

Ventricular Dysfunction, Left

Helps manage asymptomatic Left ventricular dysfunction

Effectiveness

How Vasotec Affects PatientsEnalapril is a blood pressure medication that helps reduce blood pressure in people with essential and renovascular hypertension. It usually takes several weeks to see the full effects, and its effects can last up to 24 hours. Enalapril has been shown to improve cardiac performance and reduce left ventricular mass in those with congestive heart failure, and it does not often cause bradycardia or rebound hypertension when it is stopped. It does not usually cause side effects like hypokalaemia, hyperglycaemia, hyperuricaemia, or hypercholesterolaemia. In the kidneys, it increases blood flow and reduces resistance

How Vasotec works in the bodyEnalapril works by blocking the renin-angiotensin-aldosterone system, which helps to regulate blood pressure and fluid balance in the body. When stimulated, this system causes increased release of norepinephrine from neurons and affects how the blood vessels grow, contract, and retain salt. Enalapril stops a protein called angiotensin converting enzyme (ACE) from working, which reduces levels of angiotensin II. This causes the blood vessels to widen and reduces the amount of resistance to blood flow. Lowering the resistance reduces blood pressure. There is also some evidence that enalapril may

When to interrupt dosage

The prescribed dose of Vasotec is contingent upon the diagnosed condition, including asymptomatic Left ventricular dysfunction, inadequately regulated blood pressure with monotherapy and Hypertensive disease. The measure of dosage is influenced by the methodology of delivery, as outlined in the table below.

Condition

Dosage

Administration

Ventricular Dysfunction, Left

, 2.5 mg, 5.0 mg, 10.0 mg, 20.0 mg, 5000.0 mg, 8.0 mg, 4.0 mg, 16.0 mg, 2.0 mg, 32.0 mg, 1.0 mg/mL