Zioptan

Open-angle glaucoma, Glaucoma, Open Angle Glaucoma + 1 more

Treatment

6 FDA approvals

20 Active Studies for Zioptan

Treatment for

Open-angle glaucoma

What is Zioptan

Tafluprost

The Generic name of this drug

Treatment Summary

Tafluprost is a medication that is used in eye drops to treat glaucoma and high eye pressure. It works by decreasing the amount of fluid in the eye, which helps to relieve pressure. Tafluprost was approved by the FDA in 2012 and is a chemical analogue of the hormone prostaglandin F2-alpha.

Zioptan

is the brand name

image of different drug pills on a surface

Zioptan Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Zioptan

Tafluprost

2012

Approved as Treatment by the FDA

Tafluprost, also known as Zioptan, is approved by the FDA for 6 uses which include Open Angle Glaucoma (OAG) and Increased Intra Ocular Pressure (IOP) .

Open Angle Glaucoma (OAG)

Helps manage Open Angle Glaucoma (OAG)

Increased Intra Ocular Pressure (IOP)

Helps manage Increased Intra Ocular Pressure (IOP)

Ocular Hypertension

Helps manage Ocular Hypertension

Open Angle Glaucoma

Helps manage Open Angle Glaucoma (OAG)

Glaucoma

Helps manage Increased Intra Ocular Pressure (IOP)

Ocular Hypertension

Helps manage Ocular Hypertension

Effectiveness

How Zioptan Affects Patients

Tafluprost is a new type of drug that attaches itself to the FP receptor PGF2α. It binds to this receptor 12 times more strongly than latanoprost, but does not attach to any other receptors.

How Zioptan works in the body

Tafluprost acid is a drug that helps reduce pressure in the eye. It works by increasing the outflow of fluid from the eye, allowing pressure to be relieved.

When to interrupt dosage

The suggested dosage of Zioptan is contingent upon the identified circumstance, for instance Increased Intra Ocular Pressure (IOP), Open Angle Glaucoma and Open Angle Glaucoma. The measure of dosage differs, as per the method of delivery described in the subsequent table.

Condition

Dosage

Administration

Open-angle glaucoma

, 0.045 mg/mL

, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ophthalmic

Glaucoma

, 0.045 mg/mL

, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ophthalmic

Open Angle Glaucoma

, 0.045 mg/mL

, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ophthalmic

Ocular Hypertension

, 0.045 mg/mL

, Solution, Solution - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ophthalmic

Warnings

Zioptan Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 1 known major drug interactions with Zioptan.

Common Zioptan Drug Interactions

Drug Name

Risk Level

Description

Bimatoprost

Moderate

The therapeutic efficacy of Bimatoprost can be decreased when used in combination with Tafluprost.

Zioptan Toxicity & Overdose Risk

The most common side effect of the eyes is redness in the whites of the eyes (occurring in 4-20% of cases).

image of a doctor in a lab doing drug, clinical research

Zioptan Novel Uses: Which Conditions Have a Clinical Trial Featuring Zioptan?

114 active trials are being conducted to evaluate the potential of Zioptan to manage Ocular Hypertension, Increased Intra Ocular Pressure (IOP) and Open Angle Glaucoma.

Condition

Clinical Trials

Trial Phases

Open-angle glaucoma

45 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Early Phase 1, Phase 1

Open Angle Glaucoma

9 Actively Recruiting

Phase 3, Not Applicable, Phase 4

Glaucoma

0 Actively Recruiting

Ocular Hypertension

10 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Phase 4

Zioptan Reviews: What are patients saying about Zioptan?

Patient Review

9/3/2022

Zioptan for Wide-Angle Glaucoma

This medication has been working great for me in reducing the pressure in my eyes. I haven't really noticed any negative side effects, except maybe with my balance, but I understand that can be a problem as we get older.

4.3

Patient Review

6/23/2013

Zioptan for Increased Pressure in the Eye

This medication was very effective in lowering my blood pressure, without any adverse effects. The only downside is that you can't use one vial for more than one day, and they're a bit pricey since there's no generic yet.

Patient Review

8/21/2014

Zioptan for Increased Pressure in the Eye

My doctor says this drug is perfect for me, as it doesn't contain any preservatives (to which I'm allergic). The downside is that it can cause dryness and a burning sensation. However, it has lowered my pressure beautifully.

Patient Review

12/20/2018

Zioptan for Wide-Angle Glaucoma

I've only been taking this medication for a week, but it has already worked better for me than many other medications I have tried in the past. My eyes are red, but there is no pain or itching.

3.7

Patient Review

7/31/2012

Zioptan for Wide-Angle Glaucoma

I've been using this product for a while now, and I haven't experienced any negative side effects. Additionally, there are no preservatives in Zioptan which means that there is no eye redness like with the Lumigen drop. However, you have to keep the drops refrigerated.

3.7

Patient Review

2/8/2015

Zioptan for Increased Pressure in the Eye

I experienced a number of bothersome side effects while taking this medication. These included a racing heart, shortness of breath, and stuffiness in my nasal passages. Additionally, I suffered from dry eyes, blurry vision, and dry throat/chapped lips. This was all within 6 months of starting the medication, and ultimately caused me to develop cataracts in both eyes.

3.3

Patient Review

6/22/2012

Zioptan for Increased Pressure in the Eye

This medication caused my eyes to become red and irritated, as well as giving me headaches and sinus irritation.

3.3

Patient Review

8/27/2012

Zioptan for Increased Pressure in the Eye

The dry cough and eye redness are manageable, but the heart palpitations are a bit concerning.

Patient Review

1/9/2013

Zioptan for Increased Pressure in the Eye

I experienced some heart palpitations and redness in my eyes. I also felt very dizzy.

Patient Review

2/4/2015

Zioptan for Wide-Angle Glaucoma

I've been on this medication for a little over a month and a half now, and I'm still experiencing lightheadedness and palpations. Has anyone else experienced this? How long did it last for you?

Patient Review

2/15/2015

Zioptan for Increased Pressure in the Eye

I've been experiencing sinus congestion, neck pain, and throbbing headaches for two months now. I was hoping the side effects would go away with time, but unfortunately that hasn't been the case.

2.7

Patient Review

11/27/2013

Zioptan for Wide-Angle Glaucoma

I was disappointed that this didn't do more to lower my eye pressure.

2.3

Patient Review

7/28/2013

Zioptan for Wide-Angle Glaucoma

I tried this treatment for a week and had some bad side effects like sleeplessness and indigestion. I wouldn't recommend it.

2.3

Patient Review

5/3/2022

Zioptan for Wide-Angle Glaucoma

Within three days of taking this medication, I began to experience lightening-like flashes in my eye. Additionally, a large floater appeared. However, the worst symptom by far was the vitreous gel pulling away from my eyeball which caused even more floaters, severe headaches, eye pain, blurred distance vision, and light sensitivity. This stuff is horrible and if it's truly preservative-free like they claim, then there must be something else in it that is causing all these problems.

2.3

Patient Review

3/4/2013

Zioptan for Wide-Angle Glaucoma

I developed iritis, an inflammation of the iris, after the second dose. The pain was unbearable; it felt like someone was constantly stabbing my eye with an ice pick. I also had a severe headache and became extremely sensitive to light. My co-workers said I looked like a vampire because of all the redness.

2.3

Patient Review

10/29/2013

Zioptan for Increased Pressure in the Eye

I'm choosing to discontinue this medication after only seven days due to thestuffiness in my nose which has gotten worse each day, as well as fatigue, light flashes, and dry eyes.

2.3

Patient Review

1/23/2013

Zioptan for Increased Pressure in the Eye

I have headaches, blurred vision and flashes of light when I first put the drop in. I have been on Zioptan for close 11 month to year

Patient Review

3/2/2022

Zioptan for Wide-Angle Glaucoma

My eyes felt very irritated after using this treatment. They were red and itchy, and I also experienced increased watering and sensitivity to light.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about zioptan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Zioptan used for?

"Tafluprost is used to treat high pressure inside the eye due to open-angle glaucoma or other eye diseases, such as ocular hypertension. By regulating the flow of fluid within the eye, tafluprost can help prevent blindness."

Answered by AI

Is Zioptan preservative free?

"Once a container of ZIOPTAN is opened, it can no longer be considered sterile. Any solution that is not used should be discarded immediately. ZIOPTAN can be used at the same time as other topical ophthalmic drugs to lower intraocular pressure."

Answered by AI

What is the cost of Zioptan without insurance?

"How much does Zioptan cost without insurance?

The normal retail cost of Zioptan without health insurance is $276.96 per 1, 30 Solution Solution. However, you can get a discount by using a SingleCare Zioptan coupon to pay only $183.52 for 1, 30 Solution Plas Cont of generic Zioptan."

Answered by AI

What is the generic name for Zioptan?

"At the moment, there is no cheaper generic version of Zioptan (tafluprost). However, there are some other alternatives available, such as latanoprost (Xalatan) and bimatoprost (Lumigan), which are generic medications. When it comes to Zioptan (tafluprost), how long does it take for it to work?"

Answered by AI