Bystolic

Hypertensive disease
Treatment
1 FDA approval
20 Active Studies for Bystolic

What is Bystolic

NebivololThe Generic name of this drug
Treatment SummaryNebivolol is a medication used to lower blood pressure that is made up of two different elements: one that acts as a beta-blocker and another that stimulates the heart. It has been found to be more effective at lowering blood pressure than other beta-blockers such as atenolol, propranolol, and pindolol. Although it is an effective treatment, nebivolol is usually not the first choice for high blood pressure as many patients are typically treated with thiazide diuretics first. Nebivolol was approved by the FDA in 2007.
Bystolicis the brand name
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Bystolic Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bystolic
Nebivolol
2008
90

Approved as Treatment by the FDA

Nebivolol, otherwise called Bystolic, is approved by the FDA for 1 uses like Hypertensive disease .
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)

Effectiveness

How Bystolic Affects PatientsNebivolol is a drug used to lower high blood pressure. It works by blocking certain receptors in the body, which increases stroke volume and cardiac output. The effects of the drug can last for up to two days after stopping it, and a typical dose is 5-40mg daily. People should not suddenly stop taking it, as this can worsen coronary artery disease. Diabetic patients should monitor their blood sugar levels, as Nebivolol can mask signs of low blood sugar.
How Bystolic works in the bodyNebivolol works by blocking certain hormones that regulate the heart rate and blood pressure. This leads to a slower heart rate and lower blood pressure. Nebivolol also reduces the amount of aldosterone (a hormone that causes more fluid to remain in the body) and renin (a hormone that causes narrowing of the blood vessels). This lowers the amount of fluid in the body, which makes it easier for the heart to pump. Lastly, nebivolol stimulates a hormone called nitric oxide which helps relax the blood vessels and reduce stress on the heart.

When to interrupt dosage

The amount of Bystolic is contingent upon the diagnosed affliction. The portion of medication is determined by the method of delivery, as documented in the table below.
Condition
Dosage
Administration
Hypertensive disease
2.5 mg, , 5.0 mg, 10.0 mg, 20.0 mg
, Tablet, Oral, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral

Warnings

Bystolic has eight contraindications, so it should not be implemented when having any of the afflictions mentioned in the following table.Bystolic Contraindications
Condition
Risk Level
Notes
Severe Hepatic Impairment
Do Not Combine
Heart Decompensation
Do Not Combine
Type 2 Diabetes
Do Not Combine
severe bradycardia
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Nebivolol may interact with Pulse Frequency
Heart Block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
There are 20 known major drug interactions with Bystolic.
Common Bystolic Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Nebivolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Nebivolol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Nebivolol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Nebivolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Nebivolol.
Bystolic Toxicity & Overdose RiskAn overdose of Glucotrol can cause a slow heartbeat, low blood pressure, heart failure, dizziness, low blood sugar, exhaustion, vomiting, and difficulty breathing. Treatment for an overdose may include giving intravenous atropine for the slow heartbeat, vasopressors and fluids for low blood pressure, a type of medication for heart block, medication for heart failure, medications to open up the airways, and intravenous glucose for low blood sugar.
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Bystolic Novel Uses: Which Conditions Have a Clinical Trial Featuring Bystolic?

18 active investigations are currently assessing the potential of Bystolic to ameliorate Hypertensive Disease.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
27 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Bystolic Reviews: What are patients saying about Bystolic?

4Patient Review
10/24/2021
Bystolic for Ventricular Rate Control in Atrial Fibrillation
This beta blocker is great for controlling heart rate with few side effects. The only downside is that it's very expensive; however, the good news is that a generic will soon be available from ANI pharmaceuticals.
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Patient Q&A Section about bystolic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Bystolic a good beta blocker?

"Bystolic is a good choice for an antihypertensive drug because it is less likely to cause bronchospasm than other beta blockers."

Answered by AI

What are side effects of Bystolic?

"You may experience headaches, dizziness, lightheadedness, tiredness, nausea, slow heartbeat, or trouble sleeping. Let your doctor or pharmacist know if any of these effects persist or worsen. To help reduce dizziness and lightheadedness, get up slowly when you stand from a sitting or lying position."

Answered by AI

What is Bystolic prescribed for?

"BYSTOLIC belongs to a class of drugs called beta blockers. It is typically used with other medications to treat adults with high blood pressure. BYSTOLIC is not approved for use in children under 18."

Answered by AI

Is Bystolic a good blood pressure pill?

"User reviews for Bystolic show that it is an effective treatment for high blood pressure, with an average rating of 6.2 out of 10 from a total of 199 ratings. 50% of reviewers reported a positive experience, while 33% reported a negative experience."

Answered by AI

Clinical Trials for Bystolic

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Cuffless PPG Monitor for High Blood Pressure

18+
All Sexes
Miami, FL
This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM) method using an upper arm cuff-based oscillometric BP device, in both hypertensive and normotensive individuals referred by their provider to undergo a 24-hours ABPM for clinical indication. The Awake/Asleep test, which is the primary test recommended for automated wearable cuffless BP devices that are cuff-calibrated (based on the 2023 European Society of Hypertension (ESH) recommendations for the validation of cuffless blood pressure measuring devices), will be conducted in this study. The secondary aim of the study is to assess the feasibility and convenience of the PPG-based device.
Waitlist Available
Has No Placebo
U Health (+1 Sites)Ziad Zoghby, M.D., M.B.A.Biobeat Technologies Ltd.
Have you considered Bystolic clinical trials? We made a collection of clinical trials featuring Bystolic, we think they might fit your search criteria.Go to Trials
Have you considered Bystolic clinical trials? We made a collection of clinical trials featuring Bystolic, we think they might fit your search criteria.Go to Trials
Image of University of Alberta in Edmonton, Canada.

Egg White Powder for High Blood Sugar and High Blood Pressure

18 - 70
All Sexes
Edmonton, Canada
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides. This is a feasibility study to assess the acute effect of IRW in egg white hydrolysate for the management of high sugar and blood pressure. Participants at high risk of type 2 diabetes (T2D) or having T2D will undergo 4 consecutive treatments of 1 day each (randomly), during which they will consume a standardized breakfast with a smoothie containing different protein powders. Each treatment will be separated by a minimum of 1-week. Participants in the healthy control group will undergo 1 treatment only (one day).
Phase 1
Waitlist Available
University of AlbertaJianping Wu, PhD
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CardioCare Quest for High Blood Pressure

18+
All Sexes
Flagstaff, AZ
This project aims to address healthcare disparities among Navaho people diagnosed with hypertension or prehypertension through three main objectives. Firstly, it identifies and shares insights on healthcare access disparities affecting Navaho individuals experiencing nonadherence to hypertension treatment. Secondly, the proposal develops a telehealth solution based on factors identified as knowledge gaps caused by healthcare access disparities in hypertension management; we will use the factors to design a series of engaging minigames that can be incorporated into the larger CardioCare Quest. These minigames will be co-designed with end users and clinicians. Finally, the proposal conducts comprehensive qualitative and quantitative assessments of user experiences, perceptions, and challenges with CardioCare Quest.
Recruiting
Has No Placebo
Northern Arizona University (+1 Sites)Tochukwu Ikwunne, PhD
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Food as Medicine for Cardiometabolic Health

18+
All Sexes
Boston, MA
Though the Mississippi Delta has a rich agricultural history and some of the nation's most fertile soil, residents have experienced the legacy of slavery and economic exploitation through food insecurity and poverty for generations. This project focuses on Bolivar, Washington, and Sunflower, contiguous counties in the Delta that are designated as health disparity populations. Over 65% of the 100,000 residents are Black/African American and \~30% live at or below the poverty level. Obesity rates are high and the rate of diabetes is almost double the national average. Tufts University received a grant from the National Institute of Minority Health and Health Disparities to develop, test, and evaluate a Food is Medicine program in Mississippi. The Delta Growing a Resilient, Enriching, Equitable, Nourishing food System (GREENS) Food is Medicine (FIM) Project, is a collaborative project in Bolivar, Washington, and Sunflower counties in Mississippi. The intervention involves regularly distributed fruit and vegetable produce boxes as well as nutrition education materials to the intervention group. The control group will receive produce boxes later, after they complete study activities. The project's primary goal is to improve health outcomes by creating a FIM intervention. The Delta GREENS FIM Project aims to become a model for promoting nutrition security and management of chronic conditions in varied communities nationwide.
Recruiting
Has No Placebo
Tufts UniversityChristina D Economos, PhD
Have you considered Bystolic clinical trials? We made a collection of clinical trials featuring Bystolic, we think they might fit your search criteria.Go to Trials
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