Casodex

Treatment

0 Active Studies for Casodex

What is Casodex

Bicalutamide

The Generic name of this drug

Treatment Summary

Bicalutamide is an oral medication used to treat prostate cancer. It is made up of a mixture of two different forms (R-bicalutamide and S-bicalutamide). The medication works by blocking the action of male hormones (androgens) on cancer cells.

Casodex

is the brand name

image of different drug pills on a surface

Casodex Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Casodex

Bicalutamide

1995

Effectiveness

How Casodex Affects Patients

Bicalutamide is a medicine used to treat prostate cancer. It is a nonsteroidal anti-androgen, meaning it blocks the action of male hormones (androgens) that stimulate the growth of prostate tissue, both normal and cancerous. Prostate cancer is largely affected by androgens, and can be treated with surgery or drugs that lower androgen levels. Bicalutamide is sometimes used as a single treatment, but it has not been proven to be as effective as reducing androgen levels.

How Casodex works in the body

Bicalutamide stops male hormones from attaching to cells in the prostate. This prevents these hormones from causing the prostate to grow, both normally and abnormally.

Warnings

Casodex has a single contraindication. As such, it should not be ingested when one suffers from the conditions in the below table.

Casodex Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Casodex.

Common Casodex Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Bicalutamide.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Bicalutamide.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Bicalutamide.

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Bicalutamide.

Astemizole

Major

The serum concentration of Astemizole can be increased when it is combined with Bicalutamide.

Casodex Reviews: What are patients saying about Casodex?

Patient Review

4/4/2012

Casodex for Cancer of Prostate that has Spread to Other Part of Body

I've been on this medication for five years and it has done wonders for my prostate cancer. My PSA levels have stayed low, and I attribute a lot of that success to this drug.

Patient Review

11/28/2014

Casodex for Advanced Form of Prostate Cancer

I've been on Casodex for four years now, and it's really helped me keep my PSA levels down. I haven't had any major side effects, which is great.

Patient Review

1/26/2012

Casodex for Cancer of the Prostate Gland

I feel great since my doctor prescribed this medication

4.7

Patient Review

11/21/2011

Casodex for Cancer of Prostate that has Spread to Other Part of Body

I was in a lot of pain before I started this treatment, and it took a few weeks for the medication to really start working. Even now, I still have periodic knots in my muscle, but it's manageable and doesn't stop me from living my life.

4.7

Patient Review

11/26/2014

Casodex for Cancer of Prostate that has Spread to Other Part of Body

My husband is taking Casodex as his only treatment option, since he cannot afford the Lupron shots. He's been on it for a while now and it's working well to keep him in remission. We're both very frustrated with how expensive this all is, but thankful that there are options available.

4.7

Patient Review

1/16/2014

Casodex for Cancer of Prostate that has Spread to Other Part of Body

I experienced a total loss of sexual stimulation while taking this medication. I'm not sure if the effects are reversible after stopping the medication.

4.3

Patient Review

5/21/2015

Casodex for Advanced Form of Prostate Cancer

I had no significant side effects while taking this medication. I did, however, have to get major periodontal surgery during my treatment due to bone loss.

4.3

Patient Review

12/26/2015

Casodex for Advanced Form of Prostate Cancer

I've been on this treatment for almost two years now, and it has definitely lowered my PSA levels. However, I have experienced extreme fatigue, breast tenderness, and hair loss in the first six months. These side effects are tolerable now, but they were definitely a struggle at first.

Patient Review

10/10/2013

Casodex for Cancer of the Prostate Gland

Casodex has been working well for me so far. After four months of taking it, my PSA levels dropped from 10.7 to 3.1 and then down to 3.0 two weeks later. The only side effects I've experienced are some breast tenderness and swelling, as well as a decrease in ejaculate volume; but none of these have been too bad.

Patient Review

6/26/2013

Casodex for Cancer of the Prostate Gland

I experienced dizziness, nausea, and swelling in my legs. I also lost my appetite and became constipated.

Patient Review

8/23/2011

Casodex for Cancer of Prostate that has Spread to Other Part of Body

Patient Review

4/28/2012

Casodex for Cancer of the Prostate Gland

This treatment helped me with my hot flashes.

2.3

Patient Review

6/26/2013

Casodex for Cancer of Prostate that has Spread to Other Part of Body

I've been taking this medication for six weeks now and have had trouble sleeping as well as severe itching all over my body. Additionally, my breasts are tender to the touch and my feet and ankles swell so badly that I can hardly get shoes on some days.

2.3

Patient Review

1/19/2013

Casodex for Cancer of the Prostate Gland

I used this medication to lower my PSA rating.

Patient Review

5/14/2011

Casodex for Cancer of Prostate that has Spread to Other Part of Body

Patient Review

4/1/2014

Casodex for Cancer of the Prostate Gland

I've been on Casodex for 18 months now. I get bad hot flashes, but nothing else that I can attribute to the medication. So far it seems successful, but only time will tell for sure.

Patient Q&A Section about casodex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug Casodex used for?

"Bicalutamide is a cancer treatment drug, also known by its brand name, Casodex. It is used to treat prostate cancer."

Answered by AI

Is Casodex a chemo drug?

"Casodex is not a type of chemotherapy. It is a hormone therapy used to treat prostate cancer."

Answered by AI

How long should you take Casodex for prostate cancer?

"Casodex is a medication that is taken over a long period of time. In a clinical trial, the average follow-up time was 160 weeks, or approximately three years. The amount of time you will need to take Casodex will depend on the stage of cancer."

Answered by AI

How effective is Casodex?

"The study found that Casodex, a new non-steroidal antiandrogen, is efficacious and tolerable in patients with advanced prostate cancer. The objective response rate was 55.5% and the subjective response rate was 56.1%."

Answered by AI