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What is Cefoxitin
CefoxitinThe Generic name of this drug
Treatment SummaryCefoxitin is a type of antibiotic used to treat a wide range of bacterial infections. It is administered through an intravenous injection and is derived from a bacteria called Streptomyces lactamdurans.
Mefoxinis the brand name
Cefoxitin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mefoxin
Cefoxitin
1978
36
Approved as Treatment by the FDA
Cefoxitin, also known as Mefoxin, is approved by the FDA for 29 uses which include Bacterial Infections and Peritonitis .Bacterial Infections
Peritonitis
Abdominal Abscess
Endometritis
Gynaecological infection
Lung Abscess
Urinary Tract Infection (UTI)
Osteomyelitis
Urinary tract infection
Abscess, Intra-Abdominal
Skin and Subcutaneous Tissue Bacterial Infections
Abdominal Infection
Peritonitis
Bacterial Urinary Tract Infections
Bone and Joint Infections
Endometritis
Pelvic Inflammatory Disease (PID)
Lower respiratory tract infection bacterial
Bacterial Infections
Intraabdominal Infections
surgical prophylaxis therapy
Parametritis
Influenza
Septicemia
Bacteria
Lung Abscess
Communicable Diseases
Antibiotics
Pneumonia
Effectiveness
How Cefoxitin Affects PatientsCefoxitin is a type of antibiotic used to treat infections caused by certain bacteria. It works against a wide range of bacteria, including anaerobic bacteria, which don't need oxygen to survive. Cefoxitin is also known to be very stable in the presence of molecules that break down other antibiotics, which helps it remain effective against certain bacteria.
How Cefoxitin works in the bodyCefoxitin kills bacteria by interfering with the production of their cell walls.
When to interrupt dosage
The proposed measure of Cefoxitin depends upon the identified ailment, including Communicable Diseases, Urinary Tract Infection (UTI) and Bacterial Infections. The amount of dosage is contingent upon the method of administration featured in the table beneath.Condition
Dosage
Administration
Antibiotics
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Communicable Diseases
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Peritonitis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Osteomyelitis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Urinary tract infection
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Urinary Tract Infection (UTI)
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Intraabdominal Infections
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Pelvic Inflammatory Disease (PID)
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Lung Abscess
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Endometritis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Bacterial Infections
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Parametritis
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Influenza
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Abdominal Abscess
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Pneumonia
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Animal bite
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Bacteria
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
surgical prophylaxis therapy
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Septicemia
100.0 mg/mL, , 200.0 mg/mL, 2000.0 mg, 1000.0 mg, 10000.0 mg, 100000.0 mg
, Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Injection, solution, Injection, solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous
Warnings
There are 20 known major drug interactions with Cefoxitin.Common Cefoxitin Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Cefoxitin is combined with Neomycin.
Tenofovir
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Cefoxitin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefoxitin.
Cefoxitin Toxicity & Overdose RiskThe most toxic dose of the drug in female mice and rabbits, when administered intravenously, is 8.0 g/kg and greater than 1.0 g/kg respectively. The most toxic dose in rats, when administered intraperitoneally, is greater than 10.0 g/kg.
Cefoxitin Novel Uses: Which Conditions Have a Clinical Trial Featuring Cefoxitin?
130 active clinical trials are examining the potential of Cefoxitin to alleviate Parametritis, Urinary tract infection and Endometritis.Condition
Clinical Trials
Trial Phases
Communicable Diseases
0 Actively Recruiting
Bacteria
0 Actively Recruiting
surgical prophylaxis therapy
0 Actively Recruiting
Pneumonia
16 Actively Recruiting
Not Applicable, Phase 3, Early Phase 1, Phase 2, Phase 1
Septicemia
1 Actively Recruiting
Not Applicable
Pelvic Inflammatory Disease (PID)
0 Actively Recruiting
Endometritis
0 Actively Recruiting
Parametritis
0 Actively Recruiting
Osteomyelitis
0 Actively Recruiting
Peritonitis
0 Actively Recruiting
Animal bite
0 Actively Recruiting
Antibiotics
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Abdominal Abscess
0 Actively Recruiting
Lung Abscess
0 Actively Recruiting
Urinary Tract Infection (UTI)
9 Actively Recruiting
Phase 1, Phase 3, Phase 4, Not Applicable
Influenza
38 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Phase 1
Bacterial Infections
0 Actively Recruiting
Intraabdominal Infections
1 Actively Recruiting
Not Applicable
Cefoxitin Reviews: What are patients saying about Cefoxitin?
3Patient Review
5/11/2013 I got an infection in my hip replacement, which required me to get a new hip replacement and go on IV antibiotics for six weeks. This caused severe diarrhea, which turned into C-diff after two weeks. I had to take oral vancomycin four times a day for 10 months. I also experienced extreme muscle decay during this time.
Patient Q&A Section about cefoxitin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is cefoxitin a penicillin?
"Cefoxitin is a derivative of cephamycin, and is a second-generation cephalosporin. Like other cephalosporins, it inhibits cell wall synthesis by linking with penicillin-binding proteins to create an unstable bacterial cell wall. Resistance develops by alterations in penicillin-binding proteins."
Answered by AI
What type of antibiotic is cefoxitin?
"Cefoxitin belongs to a class of antibiotics called cephamycins, which work by killing bacteria."
Answered by AI
What is IV cefoxitin used for?
"Cefoxitin injection is a medication used to treat bacterial infections in many different parts of the body. This medicine is also given before certain types of surgery to prevent infection. Cefoxitin injection is a type of cephalosporin antibiotic."
Answered by AI
What is another name for cefoxitin?
"MEFOXIN is a semi-synthetic cepha antibiotic that is sealed under nitrogen for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans."
Answered by AI