Dymista

Blepharitis allergic, Rhinitis, Vasomotor, Hay Fever + 6 more

Treatment

1 Active Study for Dymista

Treatment for

Blepharitis allergic

What is Dymista

Azelastine

The Generic name of this drug

Treatment Summary

Fluticasone propionate is a synthetic glucocorticoid medication used to treat inflammation and other conditions. It comes in the form of inhalers, nasal sprays, and topical treatments and was first approved by the FDA in 1990.

Astelin

is the brand name

image of different drug pills on a surface

Dymista Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Astelin

Azelastine

1996

56

Effectiveness

How Dymista Affects Patients

Fluticasone propionate is a drug that activates certain receptors in the body to reduce inflammation, particularly in the lungs. When used topically, it has been shown to help constrict the blood vessels in the skin.

How Dymista works in the body

Fluticasone propionate helps reduce inflammation in the lungs. Its exact mechanism is not known, but it appears to work by activating certain receptors and reducing the number of eosinophils in the lungs.

When to interrupt dosage

The prescribed dose of Dymista is contingent upon the diagnosed condition, including Sinusitis, Chronic Obstructive Pulmonary Disease (COPD) and Non-Allergic Rhinitis. The quantity of dosage shifts, as per the given delivery system (e.g. Spray, metered - Nasal or Respiratory (inhalation)) featured in the table beneath.

Condition

Dosage

Administration

Keratoconjunctivitis

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Administration, Intranasal

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

allergic eye disorders

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Rhinitis, Vasomotor

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Blepharitis allergic

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Rhinitis, Allergic

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Allergy to Tree Pollen

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Hay Fever

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Allergic Conjunctivitis (AC)

, 0.137 mg, 0.5 mg/mL, 0.2055 mg, 1.37 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 0.137 mg/pump actuation

, Nasal, Spray, metered, Spray, metered - Nasal, Spray, Spray - Nasal, Solution / drops - Ophthalmic, Ophthalmic, Intraocular, Solution / drops - Intraocular, Solution / drops

Warnings

There are 20 known major drug interactions with Dymista.

Common Dymista Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Azelastine.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Azelastine.

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Azelastine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Azelastine.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Azelastine.

Dymista Toxicity & Overdose Risk

The effects of Fluticasone Propionate on certain populations has not been extensively studied. It has been found to cause birth defects in rats, but not humans. In nursing mothers, Fluticasone Propionate may suppress growth in infants, or have other adverse effects. Children using this drug may experience adrenal suppression. Older patients may be more sensitive to side effects. Fluticasone Propionate is not different for men and women, or different races. Patients with liver problems should be monitored carefully.

image of a doctor in a lab doing drug, clinical research

Dymista Novel Uses: Which Conditions Have a Clinical Trial Featuring Dymista?

389 active trials are pursuing the utility of Dymista in relieving Nasal Congestion, House Dust Mite Allergy and Atopic Dermatitis.

Condition

Clinical Trials

Trial Phases

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Administration, Intranasal

0 Actively Recruiting

Keratoconjunctivitis

0 Actively Recruiting

Hay Fever

0 Actively Recruiting

Allergy to Tree Pollen

0 Actively Recruiting

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Rhinitis, Allergic

0 Actively Recruiting

allergic eye disorders

0 Actively Recruiting

Blepharitis allergic

0 Actively Recruiting

Dymista Reviews: What are patients saying about Dymista?

5

Patient Review

4/23/2019

Dymista for Inflammation of the Nose due to an Allergy

I had sinus surgery three times and was still constantly dealing with infections, so my ENT recommended Dymista. I've been using it nightly for six months now and have not had a single issue with my sinuses. The taste is a little strange at first, but that's the only downside I can think of. It's much better than having to take antibiotics every few months.

5

Patient Review

4/26/2022

Dymista for Non-Seasonal Allergic Runny Nose

I was first prescribed this medication by a doctor in Mexico for my allergic rhinitis-induced night coughing. I'm so pleased with how well it works; I now only use it before bed and sleep great!

5

Patient Review

6/18/2022

Dymista for Non-Seasonal Allergic Runny Nose

Even though it's pricey and not covered by Australian insurance, this medication has done wonders after years of other treatments having no effect. It's worth every penny. I don't know why other reviewers mention taste or smell; all I experience is a sharp nostril-buzz that stops immediately and gets to work!

5

Patient Review

1/6/2019

Dymista for Inflammation of the Nose due to an Allergy

This product has really helped me to breathe better and sleep through the night. My husband is also happy because I don't snore anymore.

5

Patient Review

4/23/2020

Dymista for Inflammation of the Nose due to an Allergy

This nasal spray is fantastic. I can breathe through my nose and the inflammation has gone down immediately! Is it too good to be true? I don't know, but I'm going to stick with it. It also gives me energy...

5

Patient Review

1/16/2019

Dymista for Non-Seasonal Allergic Runny Nose

This is the best nasal spray that I've used.

4.7

Patient Review

9/13/2022

Dymista for Inflammation of the Nose due to an Allergy

I've been using Dymista for three months now, and it's made a huge difference in my sinus congestion and post-nasal drip. I had sinus surgery back in January 2020, but even after that I was still struggling with breathing difficulties and a croaky voice. But since adding Dymista to my daily routine (along with some extra antihistamines for good measure), I'm finally starting to feel better. I can breathe more easily, and my voice is sounding normal again.

4

Patient Review

5/18/2022

Dymista for Inflammation of the Nose due to an Allergy

This helped me to stop snoring, stopped the sore throat and bad breath, stopped inflammation of my face, made me feel more revitalised and minimised headaches and what felt like migraines. I seem to get dehydrated on this nasal spray so I need to up my water intake when using it

4

Patient Review

6/23/2022

Dymista for Inflammation of the Nose due to an Allergy

This nasal spray is very effective at clearing up my stuffy nose. The only downside is the smell, which can be quite off-putting. Additionally, it's on the pricier side.

2

Patient Review

7/2/2022

Dymista for Non-Seasonal Allergic Runny Nose

Dymista caused me to have eczema, which was diagnosed as fungal. Now, years later, I finally got diagnosed with fragrance allergy and balsam of Peru allergy. Turns out this 'medicine' is fragranced! That is just insane. Why would one put fragrance in a nasal spray that's used against allergies?!

1

Patient Review

7/1/2018

Dymista for Inflammation of the Nose due to an Allergy

Unfortunately, this did not work for me. The smell left over is offputting, the nose releases blood coloured snot and runs forever. I am suprised this product is still being sold without a caution.

1

Patient Review

3/8/2022

Dymista for Seasonal Runny Nose

Flixanase is a much better investment than this medication. I took it alongside other antihistamines and it still didn't work for me. By the afternoon, my eyes and nose were running even more than before.

1

Patient Review

7/13/2022

Dymista for Inflammation of the Nose due to an Allergy

This caused me so many problems. Avoid it if you can. I experienced brain fog, anxiety, depression, and a really dry nose. It's not worth the trouble.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about dymista

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Dymista prescribed for?

"Dymista is a nasal spray that is used to treat allergic rhinitis and rhinoconjunctivitis in adults and children who are at least 12 years old. It is a combination of an antihistamine and a glucocorticoid."

Answered by AI

Is Dymista a steroid?

"Azelastine and fluticasone nasal is a combination medication used to treat sneezing, runny or stuffy nose, and itching caused by allergies. It is for use in adults and children who are at least 6 years old."

Answered by AI

Is Dymista the same as Flonase?

"Dymista is used to relieve symptoms of seasonal allergic rhinitis, as well as to control symptoms of non-allergic rhinitis. It contains a corticosteroid, as well as an antihistamine. Flonase is used for similar purposes, and also contains a corticosteroid."

Answered by AI

Does Dymista have side effects?

"Dymista's most common side effects are minor nosebleeds, headaches, an unpleasant taste and smell, and irritation or dryness of the nose or throat—affecting over one in 10 users."

Answered by AI

Clinical Trials for Dymista