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What is Metaproterenol Sulfate
OrciprenalineThe Generic name of this drug
Treatment SummaryA beta-adrenergic agonist is a medication used to treat asthma and other breathing problems. This medication works by stimulating the beta-adrenergic receptors in the body, which helps to relax the muscles in the airways and improve breathing.
Alupentis the brand name
Metaproterenol Sulfate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alupent
Orciprenaline
1973
10
Approved as Treatment by the FDA
Orciprenaline, also known as Alupent, is approved by the FDA for 4 uses which include Bronchospasm and Chronic Obstructive Pulmonary Disease (COPD) .Bronchospasm
Chronic Obstructive Pulmonary Disease (COPD)
Helps manage Pulmonary Emphysema
Chronic Bronchitis
Helps manage Chronic Bronchitis
Asthma
Helps manage Asthma
Effectiveness
How Metaproterenol Sulfate Affects PatientsOrciprenaline (also known as metaproterenol) is a drug used to help open the airways in the lungs. It works by activating certain receptors inside the cells that lead to the relaxation of the airway muscles and a decrease in inflammation-causing molecules.
How Metaproterenol Sulfate works in the bodyOrciprenaline is a drug that activates certain receptors in your lungs, uterus, and muscles. It works by activating a specific enzyme which then increases the production of a chemical called cAMP. This leads to the drug's effects on these organs and tissues.
When to interrupt dosage
The recommended portion of Metaproterenol Sulfate is contingent upon the diagnosed disorder, including Chronic Bronchitis, Bronchospasm and Asthma. The amount of dosage is contingent upon the procedure of administration (e.g. Oral or Liquid - Respiratory (inhalation)) featured in the table below.Condition
Dosage
Administration
Bronchospasm
10.0 mg/mL, , 10.0 mg, 20.0 mg, 0.75 mg, 6.0 mg/mL, 4.0 mg/mL, 0.65 mg, 15.0 mg/mL, 2.0 mg/mL, 50.0 mg/mL
, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Aerosol, Liquid, Solution, Solution - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Liquid - Respiratory (inhalation), Aerosol - Respiratory (inhalation)
Chronic Obstructive Pulmonary Disease (COPD)
10.0 mg/mL, , 10.0 mg, 20.0 mg, 0.75 mg, 6.0 mg/mL, 4.0 mg/mL, 0.65 mg, 15.0 mg/mL, 2.0 mg/mL, 50.0 mg/mL
, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Aerosol, Liquid, Solution, Solution - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Liquid - Respiratory (inhalation), Aerosol - Respiratory (inhalation)
Asthma
10.0 mg/mL, , 10.0 mg, 20.0 mg, 0.75 mg, 6.0 mg/mL, 4.0 mg/mL, 0.65 mg, 15.0 mg/mL, 2.0 mg/mL, 50.0 mg/mL
, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Aerosol, Liquid, Solution, Solution - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Liquid - Respiratory (inhalation), Aerosol - Respiratory (inhalation)
Chronic Bronchitis
10.0 mg/mL, , 10.0 mg, 20.0 mg, 0.75 mg, 6.0 mg/mL, 4.0 mg/mL, 0.65 mg, 15.0 mg/mL, 2.0 mg/mL, 50.0 mg/mL
, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Aerosol, Liquid, Solution, Solution - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Liquid - Respiratory (inhalation), Aerosol - Respiratory (inhalation)
Warnings
Metaproterenol Sulfate ContraindicationsCondition
Risk Level
Notes
Cardiac Arrhythmia
Do Not Combine
Common Metaproterenol Sulfate Drug Interactions
Drug Name
Risk Level
Description
Iobenguane
Major
Orciprenaline can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
1-benzylimidazole
Minor
The risk or severity of hypertension can be increased when Orciprenaline is combined with 1-benzylimidazole.
2,5-Dimethoxy-4-ethylamphetamine
Minor
The risk or severity of hypertension can be increased when Orciprenaline is combined with 2,5-Dimethoxy-4-ethylamphetamine.
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Orciprenaline is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Orciprenaline is combined with 4-Bromo-2,5-dimethoxyamphetamine.
Metaproterenol Sulfate Toxicity & Overdose RiskOverdosing on Verapamil can cause chest pain, high or low blood pressure, abnormal heart rhythms, anxiety, headaches, trembling, dry mouth, racing heartbeat, nausea, dizziness, tiredness, discomfort, and difficulty sleeping. The lowest toxic dose in rats is 42 mg/kg when taken orally.
Metaproterenol Sulfate Novel Uses: Which Conditions Have a Clinical Trial Featuring Metaproterenol Sulfate?
162 active clinical trials are assessing the potential of Metaproterenol Sulfate to provide relief for Chronic Obstructive Pulmonary Disease (COPD), Chronic Bronchitis and Asthma.Condition
Clinical Trials
Trial Phases
Bronchospasm
0 Actively Recruiting
Asthma
150 Actively Recruiting
Phase 1, Phase 2, Phase 4, Not Applicable, Early Phase 1, Phase 3
Chronic Bronchitis
4 Actively Recruiting
Not Applicable, Phase 4
Chronic Obstructive Pulmonary Disease (COPD)
8 Actively Recruiting
Phase 3, Phase 4, Phase 1, Phase 2
Patient Q&A Section about metaproterenol sulfate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects to metaproterenol?
"If you experience serious side effects from Alupent, such as an allergic reaction, chest pains, or an irregular heart beat, tell your doctor."
Answered by AI
What is metaproterenol sulfate used for?
"Metaproterenol is used to prevent and treat wheezing, shortness of breath, coughing, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases by relaxes and opens air passages in the lungs, making it easier to breathe."
Answered by AI