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What is Prostin Vr Pediatric
AlprostadilThe Generic name of this drug
Treatment SummaryAlprostadil is a medication used to widen blood vessels and improve blood flow. In infants, this drug is used to treat life-threatening heart defects by keeping the ductus arteriosus open until surgery can be performed. In adults, it is used to treat erectile dysfunction caused by a variety of factors, including nerve damage, circulation problems and psychological issues.
Prostin Vr Pediatricis the brand name
Prostin Vr Pediatric Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Prostin Vr Pediatric
Alprostadil
1981
28
Effectiveness
How Prostin Vr Pediatric Affects PatientsAlprostadil (prostaglandin E1) is a natural substance that helps relax the walls of blood vessels and increases blood flow. In adult males, this drug increases blood flow to the penis, making it harder. In infants, it increases blood flow in the lungs or body.
How Prostin Vr Pediatric works in the bodyAlprostadil works by causing the blood vessels to widen, either in the lungs or in the penis. In infants with heart conditions, it can increase oxygen supply in the body. In adults, administration of alprostadil through injection or suppository causes the penis to swell and become rigid due to increased arterial blood flow into the corpus cavernosum. This entraps blood and prevents venous outflow.
When to interrupt dosage
The advised dosage of Prostin Vr Pediatric is subject to the diagnosed affliction, including Impotence, Raynaud's Phenomenon and Aquaporin 2. The quantity of dosage shifts, in correlation with the administration process delineated in the accompanying table.Condition
Dosage
Administration
Raynaud Disease
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Aquaporin 2
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Impotence
, 0.125 mg, 0.25 mg, 0.5 mg, 1.0 mg, 0.01 mg/mL, 0.02 mg/mL, 0.04 mg/mL, 0.0232 mg, 0.0119 mg, 0.0105 mg/mL, 0.0054 mg/mL, 0.5 mg/mL, 0.0205 mg/mL, 0.1 mg/mL, 0.0411 mg/mL, 0.2 mg/mL, 0.02 mg, 0.0033 mg/mg, 0.0022 mg/mg
, Urethral, Suppository, Suppository - Urethral, Intracavernous, Injection, powder, lyophilized, for solution - Intracavernous, Injection, powder, lyophilized, for solution, Kit; Liquid; Powder, for solution - Intracavernous, Kit; Liquid; Powder, for solution, Intra-arterial; Intravenous, Solution - Intra-arterial; Intravenous, Solution, Liquid, Liquid - Intra-arterial; Intravenous, Powder, for solution - Intracavernous, Powder, for solution, Topical, Cream - Topical, Cream, Intravascular, Injection, solution, concentrate, Injection, solution, concentrate - Intravascular, Intravascular; Intravenous, Injection, solution, Injection, solution - Intravascular; Intravenous, Solution - Intravascular, Injection, Injection - Intravascular; Intravenous
Warnings
Prostin Vr Pediatric has fourteen contraindications and should not be employed in concert with the conditions listed in the table below.Prostin Vr Pediatric ContraindicationsCondition
Risk Level
Notes
predisposition to multiple myeloma
Do Not Combine
penis
Do Not Combine
Polycythemia
Do Not Combine
Thrombocytosis
Do Not Combine
predisposition to priapism
Do Not Combine
Disease
Do Not Combine
use for sexual intercourse
Do Not Combine
penile implants
Do Not Combine
leukemia
Do Not Combine
Anemia, Sickle Cell
Do Not Combine
Pulse Frequency
Do Not Combine
Erectile Dysfunction
Do Not Combine
Hyperviscosity syndrome
Do Not Combine
Pulse Frequency
Do Not Combine
Common Prostin Vr Pediatric Drug Interactions
Drug Name
Risk Level
Description
Captopril
Minor
The excretion of Captopril can be decreased when combined with Alprostadil.
Cefdinir
Minor
The excretion of Cefdinir can be decreased when combined with Alprostadil.
Citrulline
Minor
The excretion of Citrulline can be decreased when combined with Alprostadil.
Cyclic adenosine monophosphate
Minor
The excretion of Cyclic adenosine monophosphate can be decreased when combined with Alprostadil.
Didanosine
Minor
The excretion of Didanosine can be decreased when combined with Alprostadil.
Prostin Vr Pediatric Toxicity & Overdose RiskThe lowest toxic dose of this drug in mice is 186mg/kg, and 228mg/kg in rats. Signs of overdose may include difficulty breathing, slow heartbeat, fever, low blood pressure, and flushed skin.
Prostin Vr Pediatric Novel Uses: Which Conditions Have a Clinical Trial Featuring Prostin Vr Pediatric?
27 active clinical trials are currently underway to explore the efficacy of Prostin Vr Pediatric in addressing Aquaporin 2 Deficiency, Erectile Dysfunction and Raynaud's Phenomenon.Condition
Clinical Trials
Trial Phases
Aquaporin 2
1 Actively Recruiting
Phase 3
Raynaud Disease
0 Actively Recruiting
Impotence
22 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Early Phase 1, Phase 3
Prostin Vr Pediatric Reviews: What are patients saying about Prostin Vr Pediatric?
5Patient Review
10/15/2010 This treatment saved my baby's life.
Patient Q&A Section about prostin vr pediatric
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How is prostin calculated?
"The recommended starting dose of 0.1 micrograms per kilogram of body weight per minute is based on clinical studies; however, reports show that an adequate clinical response can be achieved using a starting dose of 0.05 micrograms per kilogram of body weight per minute."
Answered by AI
How do you inject prostin?
"Inject the medication into a different area on the opposite side of the penis from the site of the last dose each time. Apply pressure to the injection site with an alcohol swab for about 5 minutes after injection to prevent bruising. Do not use a bent needle to inject this medication."
Answered by AI
What is alprostadil used for in babies?
"This medicine is used to treat certain heart, lung, and blood vessel problems in infants. It helps to keep the ductus arteriosus (blood vessel in the heart) open temporarily before having a surgery. This medicine should only be given by or under the supervision of your child's doctor."
Answered by AI
What is prostin medication?
"Prostin E2 is a medication used to treat the symptoms associated with pregnancy termination. It may be used alone or in conjunction with other medications. Prostin E2 belongs to a class of drugs known as prostaglandins, vaginal preparations, and abortifacients."
Answered by AI