Methylphenidate

Narcolepsy, Attention Deficit Hyperactivity Disorder
Treatment
20 Active Studies for Methylphenidate

What is Methylphenidate

MethylphenidateThe Generic name of this drug
Treatment SummaryMethylphenidate is a medication used to treat Attention Deficit/Hyperactivity Disorder (ADHD) and narcolepsy. It is sold under the brand names Ritalin, Concerta, and Biphentin. Methylphenidate works by increasing the activity of certain brain chemicals, like dopamine and norepinephrine, which help to improve focus and attention. The effects of methylphenidate last up to 10-12 hours, so it can be taken once a day. However, methylphenidate has the potential to be abused and can cause addiction, so it is important to take it as prescribed by your doctor
Methylphenidate Hydrochlorideis the brand name
image of different drug pills on a surface
Methylphenidate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methylphenidate Hydrochloride
Methylphenidate
1955
490

Effectiveness

How Methylphenidate Affects PatientsMethylphenidate is a combination of two different isomers (d- and l-). The d-isomer is the active part of the drug, and binds to dopamine-rich areas of the brain, especially in the prefrontal cortex. This area is thought to be important in attention-deficit / hyperactivity disorder (ADHD). In animal studies, this drug has been shown to increase movement activity and cause repetitive behaviors.
How Methylphenidate works in the bodyMethylphenidate helps people with ADHD by increasing the activity of two neurotransmitters, norepinephrine and dopamine, in the brain. Low doses of methylphenidate work to reduce impulsivity and improve cognitive functions like attention and memory. It also has an effect on alpha-1 adrenergic receptors, which helps with sustained attention. People with ADHD may have genetic abnormalities that affect the dopamine transporter gene, D4 receptor gene, and D2 receptor gene. Methylphenidate can help to overcome these genetic issues by increasing dopamine activity in the brain.

When to interrupt dosage

The amount of Methylphenidate is reliant upon the diagnosed situation. The dosage quantity may differ depending upon the technique of delivery featured in the table beneath.
Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, chewable, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release - Oral, Suspension, extended release, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Narcolepsy
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, chewable, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release - Oral, Suspension, extended release, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral

Warnings

Methylphenidate Contraindications
Condition
Risk Level
Notes
advanced arteriosclerosis
Do Not Combine
Gilles de la Tourette syndrome
Do Not Combine
Thyrotoxicosis
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
Hypertensive disease
Do Not Combine
Pulse Frequency
Do Not Combine
Tension-Type Headache
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Tourette Syndrome
Do Not Combine
Pheochromocytoma
Do Not Combine
Tics
Do Not Combine
Agitation
Do Not Combine
There are 20 known major drug interactions with Methylphenidate.
Common Methylphenidate Drug Interactions
Drug Name
Risk Level
Description
Desflurane
Major
Methylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Methylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Methylphenidate may increase the hypertensive activities of Enflurane.
Halothane
Major
Methylphenidate may increase the hypertensive activities of Halothane.
Isoflurane
Major
Methylphenidate may increase the hypertensive activities of Isoflurane.
Methylphenidate Toxicity & Overdose RiskOverdosing on morphine can cause vomiting, restlessness, tremors, overactive reflexes, muscle spasms, seizures (sometimes followed by a coma), feeling happy and excited, confusion, seeing or hearing things that aren't real, delirium, sweating, redness of the face, headaches, high body temperature, rapid heartbeat, heart rhythm problems, high blood pressure, wide pupils, and dryness of the mouth. The lowest toxic dose for mice is 190mg/kg when given orally.
image of a doctor in a lab doing drug, clinical research

Methylphenidate Novel Uses: Which Conditions Have a Clinical Trial Featuring Methylphenidate?

84 active studies are presently assessing the potential of Methylphenidate to provide relief for Attention Deficit Hyperactivity Disorder.
Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
63 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2
Narcolepsy
2 Actively Recruiting
Not Applicable, Phase 1

Methylphenidate Reviews: What are patients saying about Methylphenidate?

5Patient Review
9/8/2015
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I've been using these patches for eight years now and they're still the most effective treatment I've found. It's really convenient not having to remember pills, and it doesn't screw with my diet the way some other medications can.
5Patient Review
4/8/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I have severe ADHD and this medicine makes me feel more normal than with out it. I also have depression and it helps that as well.... I actuallt dont jave any sode effects either. Hope it continues to help me.
5Patient Review
5/31/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I've only been giving my son this medication for a short time, but I'm already seeing such an amazing difference in his behavior and school performance. His teacher even contacted me to tell me how much progress he's made! I really hope that this continues to work well for him. The only side effects he's mentioned are feeling slightly dizzy and nauseous, but other than that he says he feels fine.
5Patient Review
9/8/2015
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I've been using the datrayna patches for eight years now, and they're by far the most effective treatment I've tried. I love not having to worry about forgetting pills, and it doesn't screw with my diet nearly as much as other medications have in the past.
5Patient Review
4/8/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This medication has been instrumental in managing my ADHD and depression. I haven't experienced any negative side effects, which is great.
5Patient Review
5/31/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I've only been giving my son this medication for a short time, but I've already seen such an amazing and positive difference in his behavior at school. His teacher even contacted me to tell me how well he was doing! I'm hoping the effects continue, as this has really made a world of difference for him.
4.7Patient Review
10/14/2021
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This drug is excellent for my ADHD and has helped me a lot. The only downside is that it makes me feel like a zombie, but the benefits outweigh the costs.
4.7Patient Review
7/12/2021
Methylphenidate for Recurring Sleep Episodes During the Day
This medication allowed me to focus and complete my chores for the day.
4.7Patient Review
10/14/2021
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This treatment is highly effective for my ADHD and has helped me a great deal. The only downside is that it makes me feel zombie-like; however, the benefits outweigh the costs.
4.7Patient Review
7/12/2021
Methylphenidate for Recurring Sleep Episodes During the Day
I felt more productive and focused while using this medication.
4.3Patient Review
5/27/2016
Methylphenidate for Recurring Sleep Episodes During the Day
I have a mild condition and this pill helps me with that as well as a few other disorders. It's non-addictive and the side effects are manageable. The only issue I have is sometimes I bite the inside of my mouth, but gum or hard candy takes care of that. Overall, it's been a big help in my day-to-day life.
4.3Patient Review
4/14/2018
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I have taken Adderall or Concerta for most of my life and all of my adult life. I'm currently hospitalized with a stage 4 wound located directly above my anus. During this hospitalization, they lowered my Concerta from 54mg down to 27mg. Upon my insistence and request, it has been increased to 36mg. I feel that 54mg would be a much more effective treatment.
4.3Patient Review
5/27/2016
Methylphenidate for Recurring Sleep Episodes During the Day
I have a mild condition and I found this pill to be really helpful in managing it. It's non-addictive and the side effects are manageable. The only downside is that I sometimes bite the inside of my mouth when I'm taking it, but that's an easy fix. Overall, this drug has made a big difference in my life.
4.3Patient Review
4/14/2018
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I have taken Adderall or Concerta for most of my life and all of my adult life, ironically I'm currently hospitalized with a stage 4 wound located directly above my anus. During this hospitalization they lowered my Concerta from 54mg down to 27mg and upon my insistence and a request it has been increase to 36mg. I feel that 54mg would be a much more effective treatment; however, the medical professionals here disagree.
4Patient Review
10/20/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I have found that this medication helps me to focus better on tasks. The side effects are not ideal, but manageable. For instance, I often yawn and my palms get sweaty; however, I don't feel tired. All things considered, I think this drug is working well for me.
4Patient Review
10/20/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This medication helps me focus on tasks better. The side effects are not ideal, but manageable. For example, I often yawn and my palms get sweaty; however, the drug is otherwise effective.
4Patient Review
1/18/2020
Methylphenidate for Cognitive Impairment following Traumatic Brain Injury
I may benefit from another brand name but I am afraid of what happens when I don't have it to think
4Patient Review
1/18/2020
Methylphenidate for Cognitive Impairment following Traumatic Brain Injury
I may see even better results with a different brand, but the thought of not having this medication is scary.
3.7Patient Review
1/14/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I unfortunately had to rush my daughter to the ER after just two days of taking this medication. She started having rapid heartbeats and blacking out. It was very scary for all of us.
3.7Patient Review
3/30/2021
Methylphenidate for Depression
The benefits I've experienced from this medication - more energy, focus, and happiness - have been great. It's also helped with my depression, making me feel less empty and more on-track overall. The only downside is that it doesn't last very long (I have to take it 5 times per day) and there can be some rebound effects when I stop taking it.
3.7Patient Review
1/14/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I had to rushes my daughter to the ER after only two days of taking this medication. She started having rapid heartbeats and blacking out. It was very scary for all of us.
3.7Patient Review
3/30/2021
Methylphenidate for Depression
I find that this medicine helps me be more alert and happier. The only downside is the rebound effect, where I feel worse after the effects of the drug wear off. 50mg per day
3.3Patient Review
6/18/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Terrible
3.3Patient Review
6/18/2019
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This was a terrible experience.
3Patient Review
3/17/2021
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This does help with focus problems, but it unfortunately also causes anxiety and suicidal thoughts as side effects.
3Patient Review
3/17/2021
Methylphenidate for Attention Deficit Disorder with Hyperactivity
This drug helped me focus, but I experienced side effects like anxiety and suicidal thoughts.
2Patient Review
10/24/2017
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Kremers' generic Concerta was, unfortunately, not the same as the original drug my son had been taking. He began having more severe behavior problems soon after switching, so we stopped giving it to him.
2Patient Review
4/7/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Unfortunately, this medicine came with a whole host of unsavory side effects, like a rapid heart beat, sweating, and decreased appetite. It also made it hard to concentrate and focus. While it did alleviate my condition to some degree, the side effects were not worth it.
2Patient Review
10/24/2017
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Kremers' generic Concerta was unfortunately not equivalent to the original for my son. He began having worse behavior problems after switching, so we had to go back to the old brand.
2Patient Review
4/7/2016
Methylphenidate for Attention Deficit Disorder with Hyperactivity
I experienced a whole host of negative side effects when taking this medication, including but not limited to: rapid heart rate, sweating, decreased appetite, and muscle twitching. These outweighed any benefits I saw from taking the drug, so I would not recommend it to others.
1.3Patient Review
9/29/2017
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Unfortunately, this medication had very harmful effects on my mental state. I became suicidal and ended up hurting the people around me, both mentally and physically.
1.3Patient Review
9/29/2017
Methylphenidate for Attention Deficit Disorder with Hyperactivity
Unfortunately, this medication had some pretty severe side effects for me. It made me feel incredibly suicidal and I started lashing out at the people around me, both mentally and physically.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about methylphenidate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What will methylphenidate do to a normal person?

"Do not drive after taking methylphenidate until you know how the medicine affects you, as it may cause dizziness, drowsiness, or changes in vision. Methylphenidate may also cause serious heart or blood vessel problems, which are more likely in patients with a family history of heart disease."

Answered by AI

Is methylphenidate a serious drug?

"Methylphenidate should only be used as prescribed by a doctor to avoid any serious health problems, including heart and blood pressure problems that could potentially be fatal. This medication has a risk of being habit-forming, so it should be used with caution by people who have mental/mood disorders or a substance use disorder."

Answered by AI

Is methylphenidate the same as Adderall?

"Adderall is the brand name for a mix of two stimulants called amphetamine-dextroamphetamine. Ritalin is the brand name for a stimulant called methylphenidate."

Answered by AI

Is methylphenidate a stimulant?

"Heres a rundown of how these drugs work:

These drugs work by increasing levels of the neurotransmitters dopamine and norepinephrine in the brain. This can help to improve focus, concentration, and task completion.

Stimulant medications that increase levels of dopamine and norepinephrine in the brain are often prescribed to treat children, adolescents, or adults diagnosed with attention-deficit hyperactivity disorder (ADHD). These drugs can help improve focus, concentration, and task completion."

Answered by AI

Clinical Trials for Methylphenidate

Image of St. Jude Children's Research Hospital in Memphis, United States.

Methylphenidate for Sickle Cell Disease

8 - 17
All Sexes
Memphis, TN
The purpose of this study is to determine if patients with sickle cell disease (SCD) can consistently take a drug called Methylphenidate (MPH) daily, once a day for 4 weeks to help with any thinking, attention or schoolwork problems and if they have any side effects. The study will assess any thinking or attention problems participants may have both before taking this drug and after. Additionally, the study will assess the decision-making process of the caregiver that may influence using this drug or not. Primary Objective: • Assess the feasibility, acceptability, and adherence to MPH treatment in children with SCD and EF deficits. Secondary Objective: • Evaluate neurobehavioral and safety outcomes following MPH treatment. Exploratory Objective: • Evaluate decision-making and determinants influencing methylphenidate utilization among parents.
Phase 1
Recruiting
St. Jude Children's Research HospitalAndrew Heitzer, PhD
Image of The University of Iowa in Iowa City, United States.

fMRI for Cognitive Flexibility

18 - 35
All Sexes
Iowa City, IA
The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior. Specifically, the research aims to elucidate how the mediodorsal (MD) thalamus encodes and updates "context"-the mental framework that determines which rules or actions are relevant in a given situation. This work may contribute to understanding why certain psychiatric conditions, such as schizophrenia and ADHD, involve difficulties with cognitive flexibility and control. The primary research questions are: Does the MD thalamus represent the context that organizes how working memory guides task selection? Does the MD thalamus signal when context needs to be updated after a change in task demands? Do these thalamic representations support generalization to new situations or rules? Participants will complete cognitive tasks while undergoing high-resolution brain imaging using 7-Tesla MRI. The investigators will combine behavioral data, computational modeling, and advanced neuroimaging analyses to examine how the thalamus interacts with the cortex during flexible decision-making.
Waitlist Available
Has No Placebo
The University of Iowa
Image of UCSF Nancy Friend Pritzker Psychiatry Building in San Francisco, United States.

Trigeminal Nerve Stimulation for ADHD in Children with Autism

7 - 14
All Sexes
San Francisco, CA
The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD). It will also learn about the efficacy and tolerability of the eTNS device. The main questions it aims to answer are: * Does eTNS reduce ADHD symptoms? * Does eTNS improve core and associated features of ASD? Participation spans 8-12 weeks and includes: * 4-5 in-person visits * 4 brief virtual check-ins * Nightly use of the eTNS device with a small sticky patch applied to child's forehead * Randomized assignment (those who start with the sham device may try the active device later)
Recruiting
Device
UCSF Nancy Friend Pritzker Psychiatry Building
Have you considered Methylphenidate clinical trials? We made a collection of clinical trials featuring Methylphenidate, we think they might fit your search criteria.Go to Trials
Image of Hoskinson Health and Wellness Clinic in Gillette, United States.

Biofeedback and Lifestyle Interventions for ADHD

7 - 18
All Sexes
Gillette, WY
The Pediatric Healing Minds II intervention includes a biofeedback component, breathing practices nutrition and exercise counseling. Biofeedback is a type of mind-body technique used to control body functions such as heart, lung and muscle responses. Biofeedback uses therapeutic techniques that aim to help study participants gain more awareness and control over certain physiological functions in their bodies. It involves the use of electronic monitoring equipment to provide real-time information about physiological processes such as heart rate, HRV, coherence and muscle tension. This information is then provided back to the study participant, allowing them to learn how to consciously regulate these processes. During the sessions parents are expected to attend and participate. Study participants and parents will have access to a video that provides instructions for placement of the Heart Math single small ear lobe or finger sensor. Breathing Practices include alternate nostril, qi gong and other breathing practices. Nutrition counseling includes nutrition supplementation to correct deficiencies, dietary education and an age-and gender-specific diet prescription based on the Mediterranean Diet. Exercise counseling includes developmentally appropriate guidelines for cardiopulmonary, strength and flexibility activities based on guidelines from the American College of Sports Medicine (ACSM) and the American Academy of Pediatrics (AAP). The objective of this research proposal is to examine the combined effects of an integrative approach including biofeedback, breathing practices, nutrition and exercise counseling intervention (Healing Minds II), on symptoms and severity of ADHD, impulsivity and attention (e.g., QB continuous performance test) in youth 7-18 years of age. The investigators hypothesize that ADHD symptoms and severity, impulsivity and attention will be significantly improved and coherence increased after participation in the 6-month intervention. The investigators also propose that ADHD severity in those patients with prescribed medication but poorly-controlled ADHD will demonstrate the greatest improvement compared to those not prescribed medication and those who have well-controlled ADHD.
Waitlist Available
Has No Placebo
Hoskinson Health and Wellness ClinicInara McMaster, MDHoskinson Health and Wellness Clinic
Image of Louisiana State University in Baton Rouge, United States.

Virtual Reality for ADHD

18 - 25
All Sexes
Baton Rouge, LA
The goal of this larger parallel group randomized trial is to test the impact of a virtual reality program for improving the ability of emerging adults (age 18-25) with attention deficit hyperactivity disorder (ADHD) to stay focused while completing homework and studying. This study compares the impact of using a virtual reality headset to using a virtual reality headset while also receiving feedback about levels of focus to a control group. The main question is whether participants demonstrate significantly improved concentration while completing homework and studying in virtual reality and whether they enjoy and prefer working in a virtual reality environment. Concentration is measured both through participant report and also using keyboard and mouse click data to assess work productivity objectively.
Phase 4
Waitlist Available
Louisiana State University (+1 Sites)Joshua M Langberg, PhD
Image of Duke University in Durham, United States.

Organizational Skills Training vs Mindfulness for ADHD

13 - 17
All Sexes
Durham, NC
This randomized control trial comparing Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI) among adolescents with a pre-existing ADHD diagnosis presenting to the Duke ADHD Program. Both treatments are eight 90 minute sessions. The research component will involve a pre-treatment assessment and post-treatment assessment. Both assessments will involve adolescents and one caregiver to complete questionnaires over REDCap. Rating scales will include ADHD symptom severity (Conners 3: self and parent report), functional impairment (IRS: self and parent report), executive functioning (BRIEF-2: parent report), emotion dysregulation (DERS: self and parent report), trait mindfulness (FFMQ: self report), organizational skills (BRIEF-2: parent report), treatment satisfaction (self report and parent report) and credibility (self report and parent report). Post-treatment assessments for feasibility will include attendance (measured over the course of treatment) and homework completion rates on a scale of 1 to 5 in which 5 indicates higher homework completion. We will also assess acceptability via individual items on a Likert scale (self report): overall satisfaction, how much was learned about ADHD, usefulness of information learned, content relevance to individual experience, comprehension of strategies, confidence about using strategies, likelihood of using strategies, helpfulness to share with the group, benefits from hearing from other group members, willingness to recommend the same treatment to others, and whether or not treatment was beneficial.
Recruiting
Has No Placebo
Duke UniversityJohn Mitchell, PhD
Have you considered Methylphenidate clinical trials? We made a collection of clinical trials featuring Methylphenidate, we think they might fit your search criteria.Go to Trials
Image of Montana State University in Bozeman, United States.

Speech-Gesture Combinations for Autism

Any Age
All Sexes
Bozeman, MT
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are especially disadvantaged by the lack of accessible services in their rural communities. Individuals with other cognitive profiles, including Developmental Language Disorder (DLD), ADHD, Dyslexia, and others are welcome too. The study uses methods of eye tracking and recording of brain activity to understand how hand gestures adapted from signs from American Sign Language, such as \[cry\], can promote successful understanding of words like "cry". The overarching goal is to help families effectively utilize gestures to support communication with their children.
Recruiting
Has No Placebo
Montana State University
Image of University of Pennsylvania in Philadelphia, United States.

Measurement Feedback App for Autism Spectrum Disorder

18+
All Sexes
Philadelphia, PA
The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental health outcomes in school-aged youth (ages 4-17) who receive one-to-one support in schools. The main questions it aims to answer are: 1. Does the Footsteps app improve aides' data collection quality (i.e., consistency, timeliness, and completeness)? 2. Does Footsteps use lead to improved youth behavioral health outcomes (e.g., SDQ, YTP, GAS scores)? 3. Does Footsteps improve communication and supervision processes between aides and clinical supervisors? Researchers will compare aides using Footsteps to those using a "data collection only" control app to see if Footsteps leads to higher quality data collection, enhanced supervisory communication, and better youth outcomes. Participants will: * Use either Footsteps or a control app to record de-identified data on one client's behaviors and skills over 12 weeks * Complete biweekly online surveys about data collection experiences, youth progress, and aide-supervisor communication * Participate in a virtual intake and post-trial meeting * (For a subset) Participate in a 30-45 minute qualitative interview about their experience using the app
Waitlist Available
Has No Placebo
University of PennsylvaniaHeather J Nuske, PhD
Image of Boston Children's Hospital Laboratories of Cognitive Neuroscience in Brookline, United States.

Guided Deep Breathing for ADHD

7 - 11
All Sexes
Brookline, MA
Attention-deficit/hyperactivity disorder (ADHD) affects approximately 11% of children and adolescents in the United States. Individuals with ADHD experience substantial impairments and burdens across multiple areas of daily living, including peer difficulties, academic difficulties, poor job outcomes, high rates of co-occurring disorders, and large financial costs. Although there are many well-established, evidence-based treatments for ADHD, many children continue to experience significant impairment and elevated ADHD symptoms even with prolonged treatment. Further, there are several limitations to existing treatment approaches, including medication side effects, difficulty accessing behavioral treatments, and high out-of-pocket costs for behavioral treatments. Thus, there is a crucial need to identify low cost, low burden, alternative or additive intervention approaches for pediatric ADHD. In the current pilot study, we aim to evaluate responses in behavioral and brain-based markers of attention to a mindfulness-based intervention. Mindfulness-based interventions (MBIs), including deep breathing, have received considerable research attention regarding their benefits for ADHD symptoms. Deep breathing is a strong candidate as a supplementary MBI intervention for children with ADHD due to its simplistic and easy-to-implement nature. Studies examining the effects of deep breathing on physiological arousal and ADHD symptoms in children have yielded promising results. Children will be led through a brief deep breathing intervention using a novel tool designed to optimize child engagement in deep breathing. This tool, Domi, is designed to be held in the child's hands and uses a series of haptic vibrations to provide real-time deep breathing pacing guidance. We predict that following a brief deep breathing practice, children with ADHD will demonstrate improved sustained attention, reaction time consistency, and inhibitory control. These areas of attention and behavioral functioning will be assessed using computer tasks and measures of brain activity. We plan to use the results of this study to strengthen a future application for grant funding to run a similar trial with many more children. We believe that the results of this and future studies will improve the lives of children with ADHD and their families.
Waitlist Available
Has No Placebo
Boston Children's Hospital Laboratories of Cognitive Neuroscience
Image of UPMC Magee-Womens Hospital in Pittsburgh, United States.

MomMA Intervention for ADHD

18+
Female
Pittsburgh, PA
The goal of this study is to test a behavioral program for pregnant individuals with ADHD. This behavioral program focuses on skills for managing ADHD and related symptoms in pregnancy and postpartum. This pilot effectiveness-implementation trial aims to (1) preliminarily evaluate the MomMA behavioral intervention compared to treatment as usual (TAU) on clinical outcomes and (2) evaluate implementation outcomes, including feasibility and acceptability of clinic screening within existing OB workflows; assessment and intervention protocols; provider training/fidelity to manual; and all other study protocols from the perspective of real-world providers and participants.
Waitlist Available
Has No Placebo
UPMC Magee-Womens HospitalHeather M Joseph, DO Assistant Professor of Psychiatry and Pediatrics
Have you considered Methylphenidate clinical trials? We made a collection of clinical trials featuring Methylphenidate, we think they might fit your search criteria.Go to Trials
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