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What is Omnicef
CefdinirThe Generic name of this drug
Treatment SummaryOmnicef (cefdinir) is a type of antibiotic used to treat bacterial infections in the ear, sinus, throat, lungs, and skin. It belongs to the third generation of cephalosporin antibiotics and was approved by the FDA in 1997. Omnicef is effective against bacteria that are resistant to other types of antibiotics due to their production of beta-lactamase enzymes.
Omnicefis the brand name
Omnicef Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Omnicef
Cefdinir
1997
175
Approved as Treatment by the FDA
Cefdinir, also known as Omnicef, is approved by the FDA for 22 uses including Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus and Bronchitis .Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
Bronchitis
Maxillary Sinusitis
Tonsillitis
Bronchitis, Chronic
Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenza
Haemophilus influenzae
Acute exacerbation of chronic bronchitis caused by Haemophilus parainfluenzae
Tonsillitis streptococcal
Haemophilus influenzae
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
Acute maxillary sinusitis caused by H. influenzae
Streptococcal Pharyngitis
acute otitis media caused by S.pneumoniae
Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae
Haemophilus parainfluenzae
Moraxella catarrhalis
Acute maxillary sinusitis caused by M. catarrhalis
Moraxella catarrhalis
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
Bronchitis
Moraxella catarrhalis
Effectiveness
How Omnicef Affects PatientsCefdinir is a type of medicine that kills bacteria and prevents them from multiplying. It is effective against a wide range of gram-positive and gram-negative bacteria, including those that are resistant to other cephalosporins. Cefdinir works by stopping the bacteria from building their cell walls, which helps to stop them from spreading.
How Omnicef works in the bodyCefdinir attacks bacteria in a similar way to other beta-lactam antibiotics. It works by binding to proteins that help form the bacterial cell wall. By doing this, it interferes with the cell wall's formation, which leads to cell death. Cefdinir has a stronger effect than penicillin because it has a 6-member dihydrothiazine ring instead of the 5-member thiazolidine ring found in penicillin. This 6-member ring helps the drug resist inactivation by certain bacterial enzymes and binds to penicillin-binding proteins. In addition, cefdinir
When to interrupt dosage
The measure of Omnicef is contingent upon the diagnosed disorder, including Communicable Diseases, Bronchitis and Haemophilus parainfluenzae. The magnitude of dosage is contingent upon the approach of delivering the drug (e.g. Capsule or Capsule - Oral) as outlined in the table beneath.Condition
Dosage
Administration
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Moraxella catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus influenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Moraxella catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Sinusitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Bronchitis, Chronic
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
acute otitis media caused by S.pneumoniae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Communicable Diseases
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Maxillary Sinusitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Acute maxillary sinusitis caused by M. catarrhalis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus parainfluenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Haemophilus influenzae
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Tonsillitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Tonsillitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Streptococcal Pharyngitis
300.0 mg, , 125.0 mg/mL, 250.0 mg/mL
, Oral, Capsule, Capsule - Oral, Powder, for suspension, Powder, for suspension - Oral
Warnings
Omnicef ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Cefdinir may interact with Pulse Frequency
Common Omnicef Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefdinir.
Abacavir
Minor
Cefdinir may decrease the excretion rate of Abacavir which could result in a higher serum level.
Abciximab
Minor
The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefdinir.
Aclidinium
Minor
Cefdinir may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Cefdinir may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Omnicef Toxicity & Overdose RiskThe lowest toxic dose of cefdinir in rats has been found to be greater than 2000mg/kg. Research shows that a single dose of 5600mg/kg given orally did not cause any negative side effects. Other beta-lactam antibiotics can cause nausea, vomiting, diarrhea, stomach pain, and seizures when taken in excess.
Omnicef Novel Uses: Which Conditions Have a Clinical Trial Featuring Omnicef?
Nine ongoing investigations are assessing the utility of Omnicef for the treatment of Tonsillitis, Streptococcal Pharyngitis and Communicable Diseases.Condition
Clinical Trials
Trial Phases
Streptococcal Pharyngitis
0 Actively Recruiting
Tonsillitis
4 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Haemophilus influenzae
0 Actively Recruiting
Moraxella catarrhalis
0 Actively Recruiting
Haemophilus influenzae
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Uncomplicated skin and skin structure infections caused by streptococcus pyogenes, staphylococcus aureus
0 Actively Recruiting
Sinusitis
0 Actively Recruiting
Community acquired pneumonia caused by Susceptible strains of Streptococcus pneumoniae
0 Actively Recruiting
Maxillary Sinusitis
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
3 Actively Recruiting
Not Applicable, Phase 1, Phase 3
Moraxella catarrhalis
0 Actively Recruiting
Acute maxillary sinusitis caused by Susceptible strains of Streptococcus pneumoniae
0 Actively Recruiting
Acute maxillary sinusitis caused by M. catarrhalis
0 Actively Recruiting
acute otitis media caused by S.pneumoniae
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Haemophilus parainfluenzae
0 Actively Recruiting
Moraxella catarrhalis
0 Actively Recruiting
Bronchitis, Chronic
0 Actively Recruiting
Omnicef Reviews: What are patients saying about Omnicef?
4Patient Review
9/26/2013 My daughter was given this drug after the 3rd ear infection. After the 1st does itself my baby got rashes all over the body. The doctor asked me to give for 1 more day. It made worse the next day. Tomorrow have to call the doctor and ask again.
3.7Patient Review
5/17/2016 My two year old daughter was diagnosed with a sinus infection and double ear infection and was put on cefdinir to treat these issues. After being on the medication for 5 days she started swelling all over and breaking out in a rash/hives. A trip to the ER told us she having an allergic reaction to the medication.
3.3Patient Review
11/16/2019 I was prescribed this for a UTI and, while it did clear up the infection after five days, I am now retaining urine and unable to urinate. On a catheter for a week to see if this gets resolved. Will not take this drug again; its listed side effects include decreased or inability to urinate.
3Patient Review
10/28/2013 My daughter had a double ear infection and was prescribed this medication. However, after 10 days of taking the medicine, she broke out in a rash with hives all over her body. I'm not sure if the two are related, but it's something to be aware of if you're considering this treatment for your child.
2.7Patient Review
6/15/2013 I tried this sinus infection medication today, and unfortunately it made me feel awful. I was in a lot of pain and felt nauseous. Definitely will not be recommending it to anyone.
Patient Q&A Section about omnicef
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Omnicef used to treat?
"It will not work for viral infections (such as common cold, flu).
Cefdinir is used to treat a wide variety of bacterial infections by stopping the growth of bacteria. This antibiotic only treats bacterial infections and will not work for viral infections such as the common cold or flu."
Answered by AI
Why was Omnicef discontinued?
"About 0.4% of patients had to stop taking cefdinir because they developed gastrointestinal problems like diarrhea or nausea. 19 out of 5093 patients developed a rash that was possibly caused by the medication."
Answered by AI
Is Omnicef a strong antibiotic?
"Cefdinir is an effective antibiotic against a wide range of bacteria. However, there are other antibiotics that can treat more types of infections, or more serious infections."
Answered by AI
Is Omnicef the same as amoxicillin?
"Are Omicef and Amoxicillin drugs that treat similar infections? Omnicef (cefdinir) is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic. They are both drugs that are used to treat infections, but they are in different drug classes."
Answered by AI