Triple Sulfa

Trachoma, Pink Eye, Conjunctivitis + 1 more
Treatment
6 Active Studies for Triple Sulfa

What is Triple Sulfa

SulfacetamideThe Generic name of this drug
Treatment SummarySulfabenzamide is an antimicrobial medicine used in combination with two other drugs to treat bacterial infections in the vagina.
Blephamideis the brand name
Triple Sulfa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Blephamide
Sulfacetamide
1961
61

When to interrupt dosage

The suggested dosage of Triple Sulfa is contingent upon the diagnosed condition. The measure fluctuates depending on the method of delivery outlined in the table below.
Condition
Dosage
Administration
Pink Eye
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Trachoma
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Conjunctivitis
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical
Acne Vulgaris
0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Topical, Suspension - Topical, Solution, Solution - Topical, Cream, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Liquid - Topical, Swab, Swab - Topical, Cloth, Cloth - Topical, Rinse, Rinse - Topical, Gel, Gel - Topical, Kit, Suspension / drops, Suspension / drops - Ophthalmic, Soap, Soap - Topical, Liquid - Ophthalmic, Suspension - Ophthalmic, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Warnings

Triple Sulfa Contraindications
Condition
Risk Level
Notes
Chronic Kidney Disease (CKD)
Do Not Combine
There are 17 known major drug interactions with Triple Sulfa.
Common Triple Sulfa Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Sulfacetamide.
Benzylpenicillin
Moderate
Sulfacetamide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Estetrol
Moderate
The therapeutic efficacy of Estetrol can be decreased when used in combination with Sulfacetamide.
Insulin argine
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin argine.
Insulin aspart
Moderate
The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin aspart.

Triple Sulfa Novel Uses: Which Conditions Have a Clinical Trial Featuring Triple Sulfa?

Currently, there are 0 active clinical trials investigating the potential of Triple Sulfa in treating various undetermined conditions.
Condition
Clinical Trials
Trial Phases
Trachoma
1 Actively Recruiting
Phase 4
Acne Vulgaris
2 Actively Recruiting
Phase 1, Phase 2, Early Phase 1
Pink Eye
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting

Patient Q&A Section about triple sulfa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the names of sulfa antibiotics?

"Gantrisin, Bactrim, and Septra are all sulfonamides, a class of antibiotics. Sulfadiazine and Azulfidine are also sulfonamides. Zonegran is an anticonvulsant."

Answered by AI

What does triple sulfa Treat?

"Trisulfapyrimidine, also known as triple sulfa, is a combination of sulfadiazine, sulfamerazine, and sulfamethazine. It is commonly used to treat vaginal infections, but can also be used in combination with other drugs to treat conditions ranging from skin burns to malaria and pneumonia in HIV/AIDS patients."

Answered by AI

Is triple sulfa an antibiotic?

"Triple sulfa is an antibacterial medication used to fight bacteria in the body and to treat vaginal infections caused by the bacteria Gardnerella vaginalis."

Answered by AI

What class is triple sulfa?

"Three sulfonamides, sulfadiazine, sulfamerazine, and sulfamethazine, work together to create a triple sulfa that is active against T. gondii. This combination is more effective than pyrimethamine alone."

Answered by AI

Clinical Trials for Triple Sulfa

Image of InnovaDerm in Montreal, Canada.

PF-07905428 for Acne

18 - 40
All Sexes
Montreal, Canada
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07905428) for the potential treatment of acne vulgaris. This study is seeking participants who: * Are male or female between the ages of 18 and 40 * Are generally healthy * Are diagnosed with moderate to severe acne vulgaris (Cohort 4 only) The study medicine will be applied every day on the participant's face and/or back for 14 days (Cohorts 1 and 2) or for 28 days (Cohort 3 and 4). The investigators will compare the experiences of people receiving the study medicine to those of the people who do not. This will help the investigators determine if the study medicine is safe and effective. Participants will take part in this study for approximately 2 months. During this time, they will have 17 study visits (Cohorts 1 and 2) or 31 study visits (Cohorts 3 and 4) at the study clinic. The study team will also call participants once at the end of the study over the phone.
Phase 1
Waitlist Available
InnovaDerm (+2 Sites)Pfizer CT.gov Call CenterPfizer
Image of Medical University of South Carolina in Charleston, United States.

Isotretinoin vs Tetracycline for Acne

Any Age
All Sexes
Charleston, SC
In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases. A recent study from our institution investigated a new approach: weekly Isotretinoin dosing. The results were promising, with acne improvement and no major side effects. This suggests that weekly Isotretinoin could be a successful alternative for moderate acne in both males and females. To validate these findings, investigators propose a randomized controlled trial comparing weekly Isotretinoin to daily Doxycycline over four months. This study could confirm the safety and effectiveness of weekly Isotretinoin, as well as shed light on patient satisfaction, and long-term results compared to standard antibiotics. This research may offer a breakthrough in treating moderate acne while addressing concerns about antibiotic overuse.
Phase < 1
Recruiting
Medical University of South CarolinaAlex Richmond, MD, MSCR
Image of Stanford University in Stanford, United States.

Clascoterone Cream for Acne

Any Age
All Sexes
Stanford, CA
Mechanism-based acne treatment for transgender patients receiving testosterone currently does not exist and is an unmet medical need. This study explores clascoterone to treat testosterone induced acne. Many treatments we use to treat acne in females cannot be used in transgender males because they interfere with hormone therapy. Androgens have been associated with the development of acne vulgaris. Recently, a topical androgen receptor inhibitor cream (clascoterone) has been FDA-approved for the treatment of acne. However, clinical trials of clascoterone have excluded participants on exogenous hormones. Clascoterone has been hypothesized to be effective in the treatment of acne in transgender male participants on masculinizing hormone therapy, but it has never been studied or reported in the literature.
Phase 1 & 2
Recruiting
Stanford UniversityAnne Lynn S Chang, MD
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