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BCCA - Vancouver Cancer Centre

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VANCOUVER, British Columbia V5Z 4E6

Global Leader in Breast Cancer

Global Leader in Prostate Cancer

Conducts research for Cancer

Conducts research for Lung Cancer

Conducts research for Pancreatic Cancer

539 reported clinical trials

40 medical researchers

Photo of BCCA - Vancouver Cancer Centre in VANCOUVERPhoto of BCCA - Vancouver Cancer Centre in VANCOUVERPhoto of BCCA - Vancouver Cancer Centre in VANCOUVER

Summary

BCCA - Vancouver Cancer Centre is a medical facility located in VANCOUVER, British Columbia. This center is recognized for care of Breast Cancer, Prostate Cancer, Cancer, Lung Cancer, Pancreatic Cancer and other specialties. BCCA - Vancouver Cancer Centre is involved with conducting 539 clinical trials across 383 conditions. There are 40 research doctors associated with this hospital, such as Zahi Mitri, Daniel J Renouf, MD, Anna Tinker, and Rebecca Harrison, MD.

Area of expertise

1

Breast Cancer

Global Leader

BCCA - Vancouver Cancer Centre has run 100 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
ER positive
HER2 negative
2

Prostate Cancer

Global Leader

BCCA - Vancouver Cancer Centre has run 77 trials for Prostate Cancer. Some of their research focus areas include:

Stage IV
Stage III
PSA

Top PIs

Clinical Trials running at BCCA - Vancouver Cancer Centre

Bladder Cancer

Breast Cancer

Prostate Cancer

Lung Cancer

Cancer

Ovarian Cancer

Pancreatic Cancer

Melanoma

Solid Tumors

Multiple Myeloma

Image of trial facility.

Disitamab Vedotin + Pembrolizumab vs Chemotherapy

for Bladder Cancer

This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to find out if the drugs disitamab vedotin with pembrolizumab works better than platinum-containing chemotherapy to treat patients with UC. This study will also test what side effects happen when participants take these drugs together. A side effect is anything a drug does to the body besides treating the disease. Participants in this study will have cancer that has spread through the body (metastatic) or spread near where it started (locally advanced). In this study, there are 2 different groups. Participants will be assigned to a group randomly. Participants in the disitamab vedotin arm will get the study drug disitamab vedotin once every two weeks and pembrolizumab once every 6 weeks. Participants in the standard of care arm will get gemcitabine once a week for 2 weeks with either cisplatin or carboplatin once every 3 weeks.

Recruiting

2 awards

Phase 3

Image of trial facility.

Blood Test and Immunotherapy

for Bladder Cancer

This phase II/III trial examines whether patients who have undergone surgical removal of bladder, kidney, ureter or urethra, but require an additional treatment called immunotherapy to help prevent their urinary tract (urothelial) cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or release different types of cellular products including their DNA which is referred to as circulating tumor DNA (ctDNA) into the bloodstream before changes can be seen on scans. Health care providers can measure the level of ctDNA in blood or other bodily fluids to determine which patients are at higher risk for disease progression or relapse. In this study, a blood test is used to measure ctDNA and see if there is still cancer somewhere in the body after surgery and if giving a treatment will help eliminate the cancer. Immunotherapy with monoclonal antibodies, such as nivolumab and relatlimab, can help the body's immune system to attack the cancer, and can interfere with the ability of tumor cells to grow and spread. This trial may help doctors determine if ctDNA measurement in blood can better identify patients that need additional treatment, if treatment with nivolumab prolongs patients' life and whether the additional immunotherapy treatment with relatlimab extends time without disease progression or prolongs life of urothelial cancer patients who have undergone surgical removal of their bladder, kidney, ureter or urethra.

Recruiting

1 award

Phase 2 & 3

10 criteria

Image of trial facility.

Disitamab Vedotin + Pembrolizumab

for Bladder Cancer

This trial is testing a new drug called disitamab vedotin, alone or with pembrolizumab, for patients with advanced or metastatic HER2 expressing bladder cancer. Disitamab vedotin is designed to target HER2 and has been approved for other types of cancer. The study aims to see if these drugs can effectively treat the cancer and what side effects they might cause.

Recruiting

1 award

Phase 2

4 criteria

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