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Blank Children's Hospital
Claim this profileDes Moines, Iowa 50309
Global Leader in Leukemia
Global Leader in Tumors
Conducts research for Lymphoma
Conducts research for Brain Tumor
Conducts research for Lymphoblastic Leukemia-Lymphoma
171 reported clinical trials
2 medical researchers
Summary
Blank Children's Hospital is a medical facility located in Des Moines, Iowa. This center is recognized for care of Leukemia, Tumors, Lymphoma, Brain Tumor, Lymphoblastic Leukemia-Lymphoma and other specialties. Blank Children's Hospital is involved with conducting 171 clinical trials across 322 conditions. There are 2 research doctors associated with this hospital, such as Joshua Lukenbill and Samantha L. Mallory.Area of expertise
1Leukemia
Global LeaderPhiladelphia chromosome positive
Stage II
CD5 positive
2Tumors
Global LeaderStage IV
Stage I
Stage II
Top PIs
Joshua LukenbillMedical Oncology and Hematology Associates-Des Moines4 years of reported clinical research
Expert in Cancer
Expert in Tumors
140 reported clinical trials
215 drugs studied
Samantha L. MalloryBlank Children's Hospital7 years of reported clinical research
Expert in Tumors
Expert in Brain Tumor
53 reported clinical trials
102 drugs studied
Clinical Trials running at Blank Children's Hospital
Brain Tumor
Germ Cell Tumors
Osteosarcoma
Rhabdomyosarcoma
Non-Hodgkin's Lymphoma
Langerhans Cell Histiocytosis
Tumors
Lymphoma
Acute Lymphoblastic Leukemia
Neuroectodermal Tumors
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Selumetinib vs Carboplatin/Vincristine
for Brain Cancer
This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in improving vision in subjects with LGG of the optic pathway (vision nerves). Selumetinib is a drug that works by blocking some enzymes that low-grade glioma tumor cells need for their growth. This results in killing tumor cells. Drugs used as chemotherapy, such as carboplatin and vincristine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether selumetinib works better in treating patients with NF1-associated low-grade glioma compared to standard therapy with carboplatin and vincristine.
Recruiting2 awards Phase 328 criteria
Genetic Testing-Directed Therapy
for Pediatric Cancer
This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists that has been shown to prolong survival. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic changes or abnormalities (mutations) may benefit more from treatment which targets their tumor's particular genetic mutation, and may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.
Recruiting1 award Phase 214 criteria
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Frequently asked questions
What kind of research happens at Blank Children's Hospital?
Blank Children's Hospital is a medical facility located in Des Moines, Iowa. This center is recognized for care of Leukemia, Tumors, Lymphoma, Brain Tumor, Lymphoblastic Leukemia-Lymphoma and other specialties. Blank Children's Hospital is involved with conducting 171 clinical trials across 322 conditions. There are 2 research doctors associated with this hospital, such as Joshua Lukenbill and Samantha L. Mallory.