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Blue Ridge Medical Research
Claim this profileLynchburg, Virginia 24502
Global Leader in Inflammatory Bowel Disease
Conducts research for Colorectal Cancer
Conducts research for Ulcerative Colitis
Conducts research for Ulcer
Conducts research for Esophagitis
47 reported clinical trials
1 medical researcher
Summary
Blue Ridge Medical Research is a medical facility located in Lynchburg, Virginia. This center is recognized for care of Inflammatory Bowel Disease, Colorectal Cancer, Ulcerative Colitis, Ulcer, Esophagitis and other specialties. Blue Ridge Medical Research is involved with conducting 47 clinical trials across 36 conditions. There are 1 research doctors associated with this hospital, such as Larry Clark.Top PIs
Clinical Trials running at Blue Ridge Medical Research
Ulcerative Colitis
Ulcer
Inflammatory Bowel Disease
Crohn's Disease
Esophagitis
Eosinophilic Esophagitis
Celiac Disease
Ozanimod
for Ulcerative Colitis
The purpose of this study is to explore the safety, efficacy, effects on quality of life (QOL), and biomarker response of ozanimod in participants with moderate to severely active ulcerative colitis (UC) in clinical practice.
Recruiting4 awards Phase 4
ABX464 Maintenance Therapy
for Ulcerative Colitis
This is a multicenter, randomized study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies [corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)] and/or advanced therapies [biologics (TNF inhibitors, anti-integrins, anti-IL-23), and/or S1P receptor modulators, and/or JAK inhibitors]. This study is the maintenance phase of both previous induction studies ABX464-105 and ABX464-106. All eligible subjects who have completed either one of the induction studies above mentioned, will be given the opportunity to take part in the present ABX464-107 maintenance study and will be randomized to either a double blind, placebo-controlled part (Part #1) or allocated to ABX464 50mg or 25mg open label treatment arms (Part #2) depending on their clinical response at the end of induction. This study consists of a 44-week treatment phase and a 28-days follow-up period consisting in the End of Study (EOS) visit.
Recruiting1 award Phase 3
ABX464
for Ulcerative Colitis
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrins, anti-IL-23), and/or S1P receptor modulators, and/or JAK inhibitors\].
Recruiting1 award Phase 3
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Frequently asked questions
What kind of research happens at Blue Ridge Medical Research?
Blue Ridge Medical Research is a medical facility located in Lynchburg, Virginia. This center is recognized for care of Inflammatory Bowel Disease, Colorectal Cancer, Ulcerative Colitis, Ulcer, Esophagitis and other specialties. Blue Ridge Medical Research is involved with conducting 47 clinical trials across 36 conditions. There are 1 research doctors associated with this hospital, such as Larry Clark.