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C S Mott Children's Hospital

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Ann Arbor, Michigan 48109

Global Leader in Cancer

Global Leader in Neuroblastoma

Conducts research for Solid Tumors

Conducts research for Brain Tumor

Conducts research for Acute Lymphoblastic Leukemia

370 reported clinical trials

23 medical researchers

Photo of C S Mott Children's Hospital in Ann Arbor

Summary

C S Mott Children's Hospital is a medical facility located in Ann Arbor, Michigan. This center is recognized for care of Cancer, Neuroblastoma, Solid Tumors, Brain Tumor, Acute Lymphoblastic Leukemia and other specialties. C S Mott Children's Hospital is involved with conducting 370 clinical trials across 585 conditions. There are 23 research doctors associated with this hospital, such as Rajen Mody, MD, MS, Emily B. Walling, Rama Jasty, and Andrea Franson, MD.

Area of expertise

1

Cancer

Global Leader

C S Mott Children's Hospital has run 78 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Neuroblastoma

Global Leader

C S Mott Children's Hospital has run 72 trials for Neuroblastoma. Some of their research focus areas include:

MYC positive
Stage IV
MYC negative

Top PIs

Clinical Trials running at C S Mott Children's Hospital

Brain Tumor

Cancer

Neuroblastoma

Diffuse Intrinsic Pontine Glioma

Wilms Tumor

Brain Cancer

Testicular cancer

Leukemia

Solid Tumors

Acute Lymphoblastic Leukemia

Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.

Recruiting

2 awards

Phase 3

Image of trial facility.

DAY101 vs. Chemotherapy

for Pediatric Brain Cancer

This trial is testing tovorafenib, a medication given alone, in children with a specific type of brain tumor. The drug works by blocking a protein that helps cancer cells grow.

Recruiting

2 awards

Phase 3

Image of trial facility.

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.

Recruiting

1 award

Phase 2

10 criteria

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Frequently asked questions

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