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Cancer Research Consortium of West Michigan NCORP
Claim this profileGrand Rapids, Michigan 49503
Global Leader in Cancer
Global Leader in Breast Cancer
Conducts research for Leukemia
Conducts research for Lymphoma
Conducts research for Adenocarcinoma
149 reported clinical trials
1 medical researcher
Summary
Cancer Research Consortium of West Michigan NCORP is a medical facility located in Grand Rapids, Michigan. This center is recognized for care of Cancer, Breast Cancer, Leukemia, Lymphoma, Adenocarcinoma and other specialties. Cancer Research Consortium of West Michigan NCORP is involved with conducting 149 clinical trials across 237 conditions. There are 1 research doctors associated with this hospital, such as Kathleen J. Yost.Area of expertise
1Cancer
Global LeaderStage IV
Stage III
Stage II
2Breast Cancer
Global LeaderER positive
Stage II
PR positive
Top PIs
Clinical Trials running at Cancer Research Consortium of West Michigan NCORP
Acute Lymphoblastic Leukemia
Chronic Myeloid Leukemia
Lymphoblastic Lymphoma
Lymphoma
Leukemia
Lymphoid Leukemia
Lymphoblastic Leukemia-Lymphoma
T-Cell Lymphoblastic Leukemia-Lymphoma
Acute Leukemia
Multiple Myeloma
Levocarnitine
for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma
This phase III trial compares the effect of adding levocarnitine to standard chemotherapy vs. standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting2 awards Phase 3
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Frequently asked questions
What kind of research happens at Cancer Research Consortium of West Michigan NCORP?
Cancer Research Consortium of West Michigan NCORP is a medical facility located in Grand Rapids, Michigan. This center is recognized for care of Cancer, Breast Cancer, Leukemia, Lymphoma, Adenocarcinoma and other specialties. Cancer Research Consortium of West Michigan NCORP is involved with conducting 149 clinical trials across 237 conditions. There are 1 research doctors associated with this hospital, such as Kathleen J. Yost.