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CHI Health Saint Francis
Claim this profileGrand Island, Nebraska 68803
Global Leader in Cancer
Global Leader in Lung Cancer
Conducts research for Breast Cancer
Conducts research for Adenocarcinoma
Conducts research for Non-Small Cell Lung Cancer
234 reported clinical trials
3 medical researchers
Summary
CHI Health Saint Francis is a medical facility located in Grand Island, Nebraska. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Adenocarcinoma, Non-Small Cell Lung Cancer and other specialties. CHI Health Saint Francis is involved with conducting 234 clinical trials across 422 conditions. There are 3 research doctors associated with this hospital, such as Richard L. Deming, Ryan Ramaekers, and Mehmet S. Copur.Area of expertise
1Cancer
Global LeaderStage IV
Stage III
Stage II
2Lung Cancer
Global LeaderStage IV
Stage II
Stage III
Top PIs
Richard L. DemingMercy Medical Center - Des Moines4 years of reported clinical research
Expert in Cancer
Expert in Breast Cancer
172 reported clinical trials
239 drugs studied
Ryan RamaekersCHI Health Saint Francis4 years of reported clinical research
Studies Multiple Myeloma
Studies Plasma Cell Neoplasms
3 reported clinical trials
11 drugs studied
Mehmet S. CopurBethesda North Hospital12 years of reported clinical research
Studies Breast Cancer
Studies Ovarian Cancer
2 reported clinical trials
8 drugs studied
Clinical Trials running at CHI Health Saint Francis
Breast Cancer
Lung Cancer
Non-Small Cell Lung Cancer
Bladder Cancer
Cancer
Bladder Carcinoma
Anal Cancer
Squamous Cell Carcinoma
Urothelial Carcinoma
Multiple Myeloma
Carvedilol
for Preventing Heart Problems in HER2 Positive Breast Cancer
This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it may prevent the heart from side effects of chemotherapy.
Recruiting2 awards Phase 323 criteria
T-DM1 + Tucatinib
for Breast Cancer
This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug, called DM1. Trastuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as HER2 receptors, and delivers DM1 to kill them. Tucatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving T-DM1 and tucatinib may work better in preventing breast cancer from relapsing in patients with HER2 positive breast cancer compared to T-DM1 alone.
Recruiting1 award Phase 313 criteria
Chemotherapy Reduction After Surgery
for Breast Cancer
This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment.
Recruiting1 award Phase 227 criteria
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Frequently asked questions
What kind of research happens at CHI Health Saint Francis?
CHI Health Saint Francis is a medical facility located in Grand Island, Nebraska. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Adenocarcinoma, Non-Small Cell Lung Cancer and other specialties. CHI Health Saint Francis is involved with conducting 234 clinical trials across 422 conditions. There are 3 research doctors associated with this hospital, such as Richard L. Deming, Ryan Ramaekers, and Mehmet S. Copur.