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Children's Hospital of Orange County
Claim this profileOrange, California 92868
Global Leader in Leukemia
Global Leader in Tumors
Conducts research for Lymphoma
Conducts research for Brain Tumor
Conducts research for Lymphoblastic Leukemia-Lymphoma
527 reported clinical trials
22 medical researchers
Summary
Children's Hospital of Orange County is a medical facility located in Orange, California. This center is recognized for care of Leukemia, Tumors, Lymphoma, Brain Tumor, Lymphoblastic Leukemia-Lymphoma and other specialties. Children's Hospital of Orange County is involved with conducting 527 clinical trials across 692 conditions. There are 22 research doctors associated with this hospital, such as Elyssa M. Rubin, Mariko Sato, Josephine H. Haduong, and Raymond Wang, MD.Area of expertise
1Leukemia
Global LeaderStage III
Stage IV
Stage II
2Tumors
Global LeaderStage IV
Stage I
Stage II
Top PIs
Elyssa M. RubinChildren's Hospital of Orange County7 years of reported clinical research
Expert in Tumors
Expert in Brain Tumor
53 reported clinical trials
108 drugs studied
Mariko SatoUniversity of Iowa/Holden Comprehensive Cancer Center7 years of reported clinical research
Expert in Brain Tumor
Expert in Tumors
49 reported clinical trials
95 drugs studied
Josephine H. HaduongChildren's Hospital of Orange County8 years of reported clinical research
Studies Tumors
Studies Recurrence
12 reported clinical trials
21 drugs studied
Raymond Wang, MDChildren's Hospital of Orange County (CHOC)1 year of reported clinical research
Studies Mucopolysaccharidosis
Studies Krabbe Disease
7 reported clinical trials
7 drugs studied
Clinical Trials running at Children's Hospital of Orange County
Brain Tumor
Osteosarcoma
Langerhans Cell Histiocytosis
Non-Hodgkin's Lymphoma
Lymphoma
Solid Tumors
Germ Cell Tumors
Tumors
Rhabdomyosarcoma
Rhabdoid Tumor
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Selumetinib vs Carboplatin/Vincristine
for Brain Cancer
This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in improving vision in subjects with LGG of the optic pathway (vision nerves). Selumetinib is a drug that works by blocking some enzymes that low-grade glioma tumor cells need for their growth. This results in killing tumor cells. Drugs used as chemotherapy, such as carboplatin and vincristine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether selumetinib works better in treating patients with NF1-associated low-grade glioma compared to standard therapy with carboplatin and vincristine.
Recruiting2 awards Phase 328 criteria
Selumetinib + Vinblastine
for Low-Grade Glioma
This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common type of brain cancer) that has come back after prior treatment (recurrent) or does not respond to therapy (progressive). Selumetinib is a drug that works by blocking a protein that lets tumor cells grow without stopping. Vinblastine blocks cell growth by stopping cell division and may kill cancer cells. Giving selumetinib in combination with vinblastine may work better than selumetinib alone in treating recurrent or progressive low-grade glioma.
Recruiting2 awards Phase 339 criteria
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Frequently asked questions
What kind of research happens at Children's Hospital of Orange County?
Children's Hospital of Orange County is a medical facility located in Orange, California. This center is recognized for care of Leukemia, Tumors, Lymphoma, Brain Tumor, Lymphoblastic Leukemia-Lymphoma and other specialties. Children's Hospital of Orange County is involved with conducting 527 clinical trials across 692 conditions. There are 22 research doctors associated with this hospital, such as Elyssa M. Rubin, Mariko Sato, Josephine H. Haduong, and Raymond Wang, MD.
Where is Children's Hospital of Orange County located?
**Children's Hospital of Orange County (CHOC)**
Location: 1201 W. La Veta Ave., Orange, CA
For check-in, proceed to the Bill Holmes Tower entrance located on Pepper Street and follow the signs to the front entrance.
Who should I call to ask about financial aid or insurance network?
For assistance with questions on billing, our contact process involves the following steps:
1. For billing questions, contact the **Contact Process**:
- **Phone Call**: Our **Contact Process** involves the following steps:
- For billing questions, contact the **Contact Process**:
- **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
- **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
2. **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
3. **Phone Call**: Our **Phone Call** involves the process of contacting us via phone.
What insurance does Children's Hospital of Orange County accept?
The Children's Hospital of Orange County (CHOC) accepts a wide range of insurance plans, including most major PPO, HMO, and Medicare plans. They are contracted with various managed care organizations, including Aetna, Blue Cross of California, Blue Shield of California, Cigna Healthcare, HealthNet, and United HealthCare. For specific information about coverage or inquiries regarding specialist charges, it is recommended to contact your insurance carrier or the physician directly.
What awards or recognition has Children's Hospital of Orange County received?
Children's Hospital of Orange County (CHOC) in Orange, California, is a Level I pediatric trauma center, accredited by the American College of Surgeons (ACS) and Orange County Emergency Services. It has been designated as a Rare Disease Center of Excellence, focusing on novel cures for rare disorders. Additionally, CHOC has earned Magnet recognition for nursing excellence from the American Nurses Credentialing Center for the fourth time.