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City of Hope at Irvine Lennar

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Irvine, California 92618
Global Leader in Cancer
Global Leader in Non-Small Cell Lung Cancer
Conducts research for Lung Cancer
Conducts research for Lymphoma
Conducts research for Tumors
53 reported clinical trials
30 medical researchers
Photo of City of Hope at Irvine Lennar in IrvinePhoto of City of Hope at Irvine Lennar in IrvinePhoto of City of Hope at Irvine Lennar in Irvine

Summary

City of Hope at Irvine Lennar is a medical facility located in Irvine, California. This center is recognized for care of Cancer, Non-Small Cell Lung Cancer, Lung Cancer, Lymphoma, Tumors and other specialties. City of Hope at Irvine Lennar is involved with conducting 53 clinical trials across 104 conditions. There are 30 research doctors associated with this hospital, such as Daneng Li, MD, Mark Agulnik, Vincent Chung, MD, and Marwan Fakih, MD.

Area of expertise

1Cancer
Global Leader
City of Hope at Irvine Lennar has run 19 trials for Cancer. Some of their research focus areas include:
Stage IV
HER2 positive
Stage III
2Non-Small Cell Lung Cancer
Global Leader
City of Hope at Irvine Lennar has run 16 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:
Stage IV
Stage III
EGFR positive

Top PIs

Clinical Trials running at City of Hope at Irvine Lennar

Breast Cancer
Lung Cancer
Non-Small Cell Lung Cancer
Cancer
Lymphoma
Diffuse Large B-Cell Lymphoma
Prostate Cancer
Tumors
Multiple Myeloma
Pancreatic Cancer
Image of trial facility.

Chemotherapy + Hormone Therapy

for Breast Cancer

This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.
Recruiting2 awards Phase 319 criteria
Image of trial facility.

Radiation and HER2-Targeted Therapy

for Breast Cancer

This Phase III trial compares the recurrence-free interval (RFI) among patients with early-stage, low risk HER2+ breast cancer who undergo breast conserving surgery and receive HER2-directed therapy, and are randomized to not receive adjuvant breast radiotherapy versus those who are randomized to receive adjuvant radiotherapy per the standard of care.
Recruiting2 awards Phase 315 criteria
Image of trial facility.

Durvalumab + Chemotherapy

for Breast Cancer

This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint Ultrahigh (MP2) stage II-III hormone receptor positive, HER2 negative breast cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as paclitaxel, doxorubicin, and cyclophosphamide work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. There is some evidence from previous clinical trials that people who have a MammaPrint Ultrahigh Risk result may be more likely to respond to chemotherapy and immunotherapy. Adding durvalumab to usual chemotherapy may be able to prevent the cancer from returning for patients with MP2 stage II-III hormone receptor positive, HER2 negative breast cancer.
Recruiting2 awards Phase 340 criteria

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Frequently asked questions

What kind of research happens at City of Hope at Irvine Lennar?
City of Hope at Irvine Lennar is a medical facility located in Irvine, California. This center is recognized for care of Cancer, Non-Small Cell Lung Cancer, Lung Cancer, Lymphoma, Tumors and other specialties. City of Hope at Irvine Lennar is involved with conducting 53 clinical trials across 104 conditions. There are 30 research doctors associated with this hospital, such as Daneng Li, MD, Mark Agulnik, Vincent Chung, MD, and Marwan Fakih, MD.