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Cleveland Clinic

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Cleveland, Ohio 44106
Global Leader in Cancer
Global Leader in Tumors
Conducts research for Leukemia
Conducts research for Heart Failure
Conducts research for Recurrence
3239 reported clinical trials
285 medical researchers
Photo of Cleveland Clinic in ClevelandPhoto of Cleveland Clinic in ClevelandPhoto of Cleveland Clinic in Cleveland

Summary

Cleveland Clinic is a medical facility located in Cleveland, Ohio. This center is recognized for care of Cancer, Tumors, Leukemia, Heart Failure, Recurrence and other specialties. Cleveland Clinic is involved with conducting 3,239 clinical trials across 2,192 conditions. There are 285 research doctors associated with this hospital, such as Rabi Hanna, Peter Rose, MD, Sabine s Coppieters, MD, and David Peereboom, MD.

Area of expertise

1Cancer
Global Leader
Cleveland Clinic has run 291 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage III
Stage II
2Tumors
Global Leader
Cleveland Clinic has run 144 trials for Tumors. Some of their research focus areas include:
Stage IV
Stage III
Stage I

Top PIs

Clinical Trials running at Cleveland Clinic

Lung Cancer
Non-Small Cell Lung Cancer
Prostate Cancer
Cancer
Breast Cancer
Ovarian Tumors
Acute Lymphoblastic Leukemia
Leukemia
Ovarian Cancer
Renal Cell Carcinoma
Image of trial facility.

Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.
Recruiting2 awards Phase 327 criteria
Image of trial facility.

Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
Image of trial facility.

Crizotinib

for Non-Small Cell Lung Cancer

This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-small cell lung cancer and an ALK fusion mutation.
Recruiting2 awards Phase 328 criteria

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Frequently asked questions

What kind of research happens at Cleveland Clinic?
Cleveland Clinic is a medical facility located in Cleveland, Ohio. This center is recognized for care of Cancer, Tumors, Leukemia, Heart Failure, Recurrence and other specialties. Cleveland Clinic is involved with conducting 3,239 clinical trials across 2,192 conditions. There are 285 research doctors associated with this hospital, such as Rabi Hanna, Peter Rose, MD, Sabine s Coppieters, MD, and David Peereboom, MD.
Where is Cleveland Clinic located?
**Directions to Cleveland Clinic, Cleveland, Ohio:** - **From the South:** Via I-77 or I-71, take I-90 East, exit at Chester Avenue, turn right, and proceed to East 93rd Street. - **From the Southeast or East:** Via I-271, take the Cedar Road exit, turn right on Cedar, and drive approximately eight miles to Carnegie Avenue. Then, follow Carnegie west about 1/2 mile to the CCF campus.
Who should I call to ask about financial aid or insurance network?
For financial assistance at Cleveland Clinic, reach out to the Central Business Office at 888.868.1103. To inquire about the Financial Hardship Policy or request assistance with an outstanding balance, contact the same number. For insurance-related questions, call 800.223.2273 for further assistance.
What insurance does Cleveland Clinic accept?
The Cleveland Clinic accepts a wide range of insurance plans, including but not limited to Aetna, Anthem BCBS, Cigna, Humana, Medical Mutual of Ohio, Multiplan, and United Healthcare. For Medicare patients, most plans are accepted, and coverage is through Medicare and any supplemental insurance; however, those without supplemental insurance may have a balance. Medicaid plans accepted in Ohio include AmeriHealth Caritas, Anthem Medicaid, Buckeye Community Healthplan, CareSource, Humana, Molina Healthcare, and United Healthcare Community Plan. It's advised to confirm with your insurance provider that Cleveland Clinic is included in your plan.
What awards or recognition has Cleveland Clinic received?
Cleveland Clinic is renowned for its excellence in healthcare and research, securing a spot on the U.S. News & World Report's "Best Hospitals" honor roll for 2023-24 and ranking as the No. 1 hospital for cardiology and heart surgery for the 29th consecutive year. Cleveland Clinic Children's is nationally ranked in all 10 pediatric specialties. The institution has earned numerous accolades, including the American Heart Association's Get With The Guidelines Heart Failure GOLD Plus Award, the Mitral Valve Repair Reference Center Award, and the Beacon Award of Excellence for its Heart Failure Intensive Care Unit, highlighting its commitment to patient safety, quality, and innovation.