Craig Hospital

Summary

Craig Hospital is a medical facility located in Englewood, Colorado. This center is recognized for care of Spinal Cord Injury, Traumatic Brain Injury, Cervical Cord Injury, Endothelial Dysfunction, Chronic Persistent Surgical Pain and other specialties. Craig Hospital is involved with conducting 39 clinical trials across 42 conditions. There are 0 research doctors associated with this hospital, such as .

Top PIs

Clinical Trials running at Craig Hospital

Spinal Cord Injury

Endothelial Dysfunction

Traumatic Brain Injury

Cardiovascular Disease

Cognitive Impairment

Low Testosterone

Pararenal Aneurysms

Bowel Incontinence

Neurogenic Bowel

Hypertension

Vasoactive Agents

for Endothelial Dysfunction After Spinal Cord Injury

This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.

Recruiting

1 award

N/A

7 criteria

Testosterone

for Spinal Cord Injury

Heart attacks and strokes are among the most common causes of premature death in individuals living with spinal cord injury (SCI) and appear to occur earlier in life. The factors that lead to the heighten and accelerated risk of heart attacks and strokes in adults living with SCI remain poorly understood. The investigators aim to uncover why this happens and find ways to prevent it. Our research focuses on how important cells which line blood vessels, called endothelial cells, function after SCI. The investigators test endothelial function in live conscious people with SCI. The investigators also study signaling molecules endothelial cells release called endothelial cell derived microvesicles (EMVs), which the investigators can measure in blood to tell us the health of endothelial cells. By using these rigorous tests of vascular function, the investigators have determined that endothelial cells appear dysfunctional after SCI. The investigators also know that many men with SCI have low testosterone levels. Our team has studied testosterone's effects on endothelial dysfunction and believe low testosterone may be contributing to endothelial dysfunction after SCI. By understanding these mechanisms, the investigators hope to improve the lives of those living with SCI and reduce their risk for heart attacks and strokes. The investigators propose to study the influence of testosterone on endothelial function by using state-of-the-art clinical and laboratory experiments to assess endothelial function in men with SCI with low and normal testosterone levels.

Recruiting

1 award

N/A

5 criteria

Electrical Stimulation

for Spinal Cord Injury

The primary objective of this study is to gather information about the effectiveness of abdominal FES to improve bowel management time (BMT) for people with chronic SCI. This study will also evaluate whether abdominal FES can improve: 1) bowel-related quality of life, 2) participant-reported bowel function, 3) bowel management strategy, 4) bladder symptoms, and 5) unplanned hospital admissions. In addition, we will also explore participant perspectives and experiences about the stimulation sessions and use of the device.

Recruiting

1 award

N/A