Fenway Community Health

Summary

Fenway Community Health is a medical facility located in Boston, Massachusetts. This center is recognized for care of HIV Infection, Human Immunodeficiency Virus Infection, HIV/AIDS, AIDS, Medication Adherence and other specialties. Fenway Community Health is involved with conducting 92 clinical trials across 78 conditions. There are 7 research doctors associated with this hospital, such as Kenneth Mayer, MD, Ken Mayer, MD, Peter R Chai, MD, MMS, and Conall O'Cleirigh, PhD.

Top PIs

Clinical Trials running at Fenway Community Health

Drug Addiction

HIV/AIDS

AIDS

HIV (Human Immunodeficiency Virus)

PrEP

HIV Infection

Medication Adherence

Treatment Adherence and Compliance

Noncompliance

Addiction

SmartSteps Intervention

for HIV Prevention

This is a single-arm, observational study of HIV-negative MSM with substance use disorder. Those who meet pre-screening criteria will attend a Screening Visit (Visit 1), where the informed consent process will be conducted and study eligibility will be confirmed. Eligible participants will attend three additional visits over the course of the study - the Enrollment Visit (Visit 2), Month 1 Visit (Visit 3), and Month 2 Visit (Visit 4). Participants will take one PrEP digital pill per day, for 60 days total, while using the digital pill system (DPS) and Beiwe, a digital phenotyping app. On nonadherent days, participants will receive brief surveys prompting them to report the reasons for their missed dose, as well as their engagement in substance use and sexual activity. Timeline followback will be conducted at the Month 1 and Month 2 Visits to understand the context of any nonadherence. Qualitative user experience exit interviews and dried blood spots (DBS) will be conducted at the Month 2 Visit.

Recruiting

2 awards

Phase 3

8 criteria

Text-Based Intervention

for HIV and Substance Use Disorders

People living with HIV and substance use disorders (SUDs) are less likely to be virally suppressed, which can lead to HIV transmission and negative health outcomes. This hybrid type 1 study will assess the efficacy, mechanisms, as well as facilitators and barriers to implementing the MATTER intervention, a virtually delivered 5-session text-enhanced psychobehavioral intervention designed to facilitate viral suppression by addressing internalized stigma and shame as barriers to engagement in HIV care among individuals living with HIV and SUDs in two locations with different levels of HIV resources (i.e., the Boston, Massachusetts and Miami, Florida metro areas). MATTER aims to mitigate the negative behavioral consequences of internalized stigma and shame on viral suppression by a) developing behavioral self-care goal setting skills and related self-efficacy, b) increasing metacognitive awareness (i.e., non-judgmental awareness of emotions and cognitions), and c) teaching and reinforcing compassionate self-restructuring (i.e., self- compassion), in addition to providing access to phone-based resource navigation. Scalable interventions such as MATTER are essential to our efforts to end the HIV epidemic in high priority regions.

Recruiting

1 award

N/A

11 criteria