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McGuire VA Medical Center
Claim this profileBurke, Virginia 22015
Global Leader in Liver Cirrhosis
Global Leader in Fibrosis
Conducts research for Prostate Cancer
Conducts research for Non-alcoholic Fatty Liver Disease
Conducts research for Fatty Liver Disease
141 reported clinical trials
30 medical researchers
Summary
McGuire VA Medical Center is a medical facility located in Burke, Virginia. This center is recognized for care of Liver Cirrhosis, Fibrosis, Prostate Cancer, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease and other specialties. McGuire VA Medical Center is involved with conducting 141 clinical trials across 248 conditions. There are 30 research doctors associated with this hospital, such as Jasmohan Bajaj, MD, Lance Goetz, MD, Denise Lester, MD, and Howard Li.Top PIs
Jasmohan Bajaj, MDHunter Holmes McGuire VA Medical Center1 year of reported clinical research
Studies Liver Cirrhosis
Studies Fibrosis
7 reported clinical trials
8 drugs studied
Lance Goetz, MDHunter Holmes McGuire VA Medical Center2 years of reported clinical research
Studies Spinal Cord Injury
Studies Wounds and Injuries
3 reported clinical trials
6 drugs studied
Denise Lester, MDHunter Holmes McGuire Veterans Affairs Medical Center4 years of reported clinical research
Studies Lower Back Pain
Studies Back Pain
2 reported clinical trials
4 drugs studied
Howard LiHunter Holmes McGuire Veterans Administration Medical Center3 years of reported clinical research
Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
2 reported clinical trials
2 drugs studied
Clinical Trials running at McGuire VA Medical Center
Prostate Cancer
Lung Cancer
Liver Cirrhosis
Fibrosis
Spinal Cord Injury
Liver Failure
Heart Failure
Non-Small Cell Lung Cancer
Parkinson's Disease
Liver Disease
Pembrolizumab
for Prostate Cancer
The primary objective is to assess the activity and efficacy of pembrolizumab, a checkpoint inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either mismatch repair deficiency (dMMR) or biallelic inactivation of CDK12 (CDK12-/-). The secondary objectives involve determining the frequency with which dMMR and CDK12-/- occur in this patient population, as well as the effects of pembrolizumab on various clinical endpoints (time to PSA progression, maximal PSA response, time to initiation of alternative anti-neoplastic therapy, time to radiographic progression, overall survival, and safety and tolerability). Lastly, the study will compare the pre-treatment and at-progression metastatic tumor biopsies to investigate the molecular correlates of resistance and sensitivity to pembrolizumab via RNA-sequencing, exome-sequencing, selected protein analyses, and multiplexed immunofluorescence.
Recruiting2 awards Phase 23 criteria
Systemic + Local Therapy
for Prostate Cancer
This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-resistant prostate cancer-free survival (CRPC-free survival) for Veterans with oligometastatic prostate cancer. Oligometastasis will be defined as 1-10 sites of metastatic disease based on the clinical determination of the LSI which incorporates all imaging, clinical, and pathologic data available.
Recruiting1 award Phase 2 & 33 criteria
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Frequently asked questions
What kind of research happens at McGuire VA Medical Center?
McGuire VA Medical Center is a medical facility located in Burke, Virginia. This center is recognized for care of Liver Cirrhosis, Fibrosis, Prostate Cancer, Non-alcoholic Fatty Liver Disease, Fatty Liver Disease and other specialties. McGuire VA Medical Center is involved with conducting 141 clinical trials across 248 conditions. There are 30 research doctors associated with this hospital, such as Jasmohan Bajaj, MD, Lance Goetz, MD, Denise Lester, MD, and Howard Li.