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Nemours Childrens Clinic
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Jacksonville, Florida 32207
Global Leader in Cancer
Global Leader in Brain Tumor
Conducts research for Leukemia
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Neuroblastoma
418 reported clinical trials
9 medical researchers
Summary
Nemours Childrens Clinic is a medical facility located in Jacksonville, Florida. This center is recognized for care of Cancer, Brain Tumor, Leukemia, Acute Lymphoblastic Leukemia, Neuroblastoma and other specialties. Nemours Childrens Clinic is involved with conducting 418 clinical trials across 505 conditions. There are 9 research doctors associated with this hospital, such as Scott M. Bradfield, Ramamoorthy Nagasubramanian, Emi H. Caywood, and Kathryn Blake, PharmD.
Area of expertise
Cancer
Nemours Childrens Clinic has run 64 trials for Cancer. Some of their research focus areas include:
Brain Tumor
Nemours Childrens Clinic has run 58 trials for Brain Tumor. Some of their research focus areas include:
Top PIs
Scott M. Bradfield
Alfred I duPont Hospital for Children
8 years of reported clinical research
Ramamoorthy Nagasubramanian
Nemours Children's Clinic-Jacksonville
5 years of reported clinical research
Emi H. Caywood
Alfred I duPont Hospital for Children
7 years of reported clinical research
Kathryn Blake, PharmD
Nemours Children's Health System
4 years of reported clinical research
Clinical Trials running at Nemours Childrens Clinic
Brain Tumor
Cancer
Testicular cancer
Wilms Tumor
Burkitt Lymphoma
Leukemia
Neuroblastoma
Acute Lymphoblastic Leukemia
Cystic Fibrosis
Biphenotypic Leukemia
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting
2 awards
Phase 3
Lower Radiotherapy Dose
for Brain Tumors
This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.
Recruiting
1 award
Phase 2
10 criteria
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting
1 award
Phase 2
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Frequently asked questions
What kind of research happens at Nemours Childrens Clinic?
Nemours Childrens Clinic is a medical facility located in Jacksonville, Florida. This center is recognized for care of Cancer, Brain Tumor, Leukemia, Acute Lymphoblastic Leukemia, Neuroblastoma and other specialties. Nemours Childrens Clinic is involved with conducting 418 clinical trials across 505 conditions. There are 9 research doctors associated with this hospital, such as Scott M. Bradfield, Ramamoorthy Nagasubramanian, Emi H. Caywood, and Kathryn Blake, PharmD.
Where is Nemours Childrens Clinic located?
**Nemours Children's Clinic, Jacksonville, FL** - **Address:** 4600 Touchton Rd E, Jacksonville, FL 32246 - **Services:** For convenient scheduling, viewing test results, and more, use the Nemours app.
Who should I call to ask about financial aid or insurance network?
Nemours Children's Clinic offers financial assistance and insurance support. For assistance, contact their financial department at (844) 551-2065 or for billing inquiries, call customer service at (866) 390-3610, available Monday through Friday, 8 a.m. to 4 p.m. EST. The Nemours Financial Assistance Program (NFAP) provides care at discounted rates or for free to eligible patients, with eligibility based on 250% to 300% of the Federal Poverty Level Guidelines.
What insurance does Nemours Childrens Clinic accept?
Nemours Children's Health accepts a variety of insurance plans. For detailed information on specific insurance plans accepted at the Nemours Children's Clinic location, please contact the clinic directly or visit their official website.
What awards or recognition has Nemours Childrens Clinic received?
Nemours Children's Clinic in Jacksonville, Florida, is a recipient of significant funding from the National Institutes of Health (NIH), including a recent NIH R01 grant. The clinic collaborates with prestigious institutions such as Wolfson Children's Hospital, University of Florida Health Jacksonville, and Mayo Clinic Jacksonville for clinical research studies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.