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Saint Luke's Hospital
Claim this profileChesterfield, Missouri 63017
Global Leader in Cancer
Global Leader in Breast Cancer
Conducts research for Lung Cancer
Conducts research for Lymphoma
Conducts research for Non-Small Cell Lung Cancer
141 reported clinical trials
3 medical researchers
Summary
Saint Luke's Hospital is a medical facility located in Chesterfield, Missouri. This center is recognized for care of Cancer, Breast Cancer, Lung Cancer, Lymphoma, Non-Small Cell Lung Cancer and other specialties. Saint Luke's Hospital is involved with conducting 141 clinical trials across 299 conditions. There are 3 research doctors associated with this hospital, such as Joseph Sokhn, Mark J. Fesler, and Donald F. Busiek.Area of expertise
1Cancer
Global LeaderStage IV
Stage III
Stage II
2Breast Cancer
Global LeaderHER2 positive
ER positive
Stage IV
Top PIs
Joseph SokhnSaint Luke's Hospital4 years of reported clinical research
Expert in Cancer
Studies Lung Cancer
28 reported clinical trials
87 drugs studied
Mark J. FeslerSaint Luke's Hospital3 years of reported clinical research
Studies Lymphoma
Studies B-Cell Lymphoma
8 reported clinical trials
20 drugs studied
Donald F. BusiekSaint Luke's Hospital9 years of reported clinical research
Studies Cancer
Studies Breast Cancer
6 reported clinical trials
12 drugs studied
Clinical Trials running at Saint Luke's Hospital
Breast Cancer
Non-Small Cell Lung Cancer
Lung Cancer
Lymphoma
Diffuse Large B-Cell Lymphoma
Cancer
Multiple Myeloma
B-Cell Lymphoma
Bladder Cancer
Mantle Cell Lymphoma
Chemotherapy Reduction After Surgery
for Breast Cancer
This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment.
Recruiting1 award Phase 227 criteria
Targeted Therapy
for Solid Tumors
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) and have progressed on at least one line of standard systemic therapy or have no standard treatment that has been shown to prolong overall survival may be candidates for these trials. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with some genetic changes or abnormalities (mutations) may benefit from treatment that targets that particular genetic mutation. ComboMATCH is designed to match patients to a treatment that may work to control their tumor and may help doctors plan better treatment for patients with locally advanced or advanced solid tumors.
Recruiting1 award Phase 217 criteria
Marker-Directed Monitoring
for Breast Cancer
This trial studies if using blood tests to decide when to do scans is as effective as the standard way for monitoring patients with a specific type of breast cancer that has spread. The blood tests act like an early warning system for cancer activity.
Recruiting1 award N/A
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Frequently asked questions
What kind of research happens at Saint Luke's Hospital?
Saint Luke's Hospital is a medical facility located in Chesterfield, Missouri. This center is recognized for care of Cancer, Breast Cancer, Lung Cancer, Lymphoma, Non-Small Cell Lung Cancer and other specialties. Saint Luke's Hospital is involved with conducting 141 clinical trials across 299 conditions. There are 3 research doctors associated with this hospital, such as Joseph Sokhn, Mark J. Fesler, and Donald F. Busiek.