Texas Oncology - Tyler

Summary

Texas Oncology - Tyler is a medical facility located in Tyler, Texas. This center is recognized for care of Breast Cancer, Cancer, Lung Cancer, Pancreatic Cancer, Non-Small Cell Lung Cancer and other specialties. Texas Oncology - Tyler is involved with conducting 310 clinical trials across 227 conditions. There are 7 research doctors associated with this hospital, such as Donald A. Richards, Habte A Yimer, Anna Priebe, MD, and Sasha Davis.

Top PIs

Clinical Trials running at Texas Oncology - Tyler

Colorectal Cancer

Breast Cancer

Cancer

Chronic Lymphocytic Leukemia

Lung Cancer

Ovarian Cancer

Endometrial Cancer

Multiple Myeloma

Small Cell Lung Cancer

Solid Tumors

PF-08634404 + Chemotherapy

for Colorectal Cancer

The purpose of this study is to learn more about a new medicine called PF-08634404, and how well it works in people with cancer of the colon or rectum (CRC)). The goal is to understand if the new study medicine, combined with chemotherapy that is approved for colorectal cancer, can help people whose cancer has spread or returned after treatments taken before. To join the study, participants must meet the following conditions: * Be 18 years or older. * Have colorectal cancer that has spread to other parts of your body. * Be in good enough health to receive study treatment. * Should not be pregnant before starting treatment. Participants will be randomized (like flipping a coin) to one of 2 different treatment arms. The first arm (Arm A) will include the new medicine PF-08634404 in combination with chemotherapy that is approved for colorectal cancer, and the second arm (Arm B) will include an approved medicine for colorectal cancer, called Bevacizumab, in combination with chemotherapy that is approved for this type of cancer. Participants and their doctors will not know which arm they are being assigned to. Participants will receive all the study medications through intravenous (IV) infusions, which means the medicine is given directly into a vein. The treatment will be given in cycles, and participants may continue receiving it if it is helping and they are not experiencing serious side effects. The medicine will be given at a clinical site, where trained medical staff will check participants during and after each treatment. * The study is expected to last approximately 33 months for each participant. * Participants will have regular visits to the study site for treatment, health checks, and tests. * After stopping treatment, participants will return for a final visit about 30 to37 days later to check their health and review any side effects. * Follow-up will continue every 12 weeks by phone or in person or by reviewing health records to check on health status and any new treatments.

Recruiting

2 awards

Phase 3

3 criteria

MCLA-158

for Solid Cancers

This trial is testing a new drug called MCLA-158 to see if it can help treat certain cancers by blocking a protein that helps cancer cells grow. It focuses on patients with cancers that rely on this protein, like colorectal and head and neck cancers.

Recruiting

1 award

Phase 1 & 2

SR-8541A + Combination Therapy

for Colorectal Cancer

This is an open-label, dose escalation and expansion, multi-center phase 2 study evaluating the safety and efficacy of SR-8541A administered orally in combination with intravenous botensilimab and balstilimab in subjects with MSS-CRC with and without active liver metastases.

Recruiting

1 award

Phase 2

6 criteria