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Toledo Clinic Cancer Centers-Toledo
Claim this profileToledo, Ohio 43623
Global Leader in Cancer
Global Leader in Breast Cancer
Conducts research for Adenocarcinoma
Conducts research for Non-Small Cell Lung Cancer
Conducts research for Lung Cancer
210 reported clinical trials
2 medical researchers
Summary
Toledo Clinic Cancer Centers-Toledo is a medical facility located in Toledo, Ohio. This center is recognized for care of Cancer, Breast Cancer, Adenocarcinoma, Non-Small Cell Lung Cancer, Lung Cancer and other specialties. Toledo Clinic Cancer Centers-Toledo is involved with conducting 210 clinical trials across 317 conditions. There are 2 research doctors associated with this hospital, such as REX MOWAT, MD and Mowat Rex, MD.Area of expertise
1Cancer
Global LeaderStage IV
Stage III
Stage II
2Breast Cancer
Global LeaderStage IV
HER2 negative
ER positive
Top PIs
REX MOWAT, MDToledo Clinic Cancer Centers-Toledo4 years of reported clinical research
Expert in Cancer
Expert in Breast Cancer
79 reported clinical trials
151 drugs studied
Mowat Rex, MDToledo Clinic Cancer Centers6 years of reported clinical research
Studies Adenocarcinoma
Studies Pancreatic Adenocarcinoma
1 reported clinical trial
4 drugs studied
Clinical Trials running at Toledo Clinic Cancer Centers-Toledo
Breast Cancer
Non-Small Cell Lung Cancer
Lung Cancer
Cancer
Pancreatic Cancer
Pancreatic Carcinoma
Squamous Cell Carcinoma
Colon Cancer
Melanoma
Cutaneous Melanoma
Shorter Chemo-Immunotherapy Without Anthracyclines
for Breast Cancer
This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. Cyclophosphamide is in a class of medications called alkylating agents. It works by damaging the cell's deoxyribonucleic acid (DNA) and may kill cancer cells. It may also lower the body's immune response. Docetaxel is in a class of medications called taxanes. It stops cancer cells from growing and dividing and may kill them. Doxorubicin is an anthracycline chemotherapy drug that damages DNA and may kill cancer cells. Pembrolizumab may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Shorter treatment without anthracycline chemotherapy may work the same as the usual anthracycline chemotherapy treatment for early-stage triple negative breast cancer.
Recruiting2 awards Phase 347 criteria
Pembrolizumab
for Triple-Negative Breast Cancer
The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observation will result in the same risk of cancer coming back as pembrolizumab after surgery in triple-negative breast cancer patients who achieve pathologic complete response after preoperative chemotherapy with pembrolizumab.
Recruiting2 awards Phase 319 criteria
Sacituzumab Govitecan + Pembrolizumab
for Triple Negative Breast Cancer
The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.
Recruiting2 awards Phase 36 criteria
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Frequently asked questions
What kind of research happens at Toledo Clinic Cancer Centers-Toledo?
Toledo Clinic Cancer Centers-Toledo is a medical facility located in Toledo, Ohio. This center is recognized for care of Cancer, Breast Cancer, Adenocarcinoma, Non-Small Cell Lung Cancer, Lung Cancer and other specialties. Toledo Clinic Cancer Centers-Toledo is involved with conducting 210 clinical trials across 317 conditions. There are 2 research doctors associated with this hospital, such as REX MOWAT, MD and Mowat Rex, MD.