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University of Alabama at Birmingham
Claim this profileBirmingham, Alabama 35205
Global Leader in Fibrosis
Global Leader in Breast Cancer
Conducts research for Cancer
Conducts research for Lymphoma
Conducts research for Human Immunodeficiency Virus Infection
2622 reported clinical trials
275 medical researchers
Summary
University of Alabama at Birmingham is a medical facility located in Birmingham, Alabama. This center is recognized for care of Fibrosis, Breast Cancer, Cancer, Lymphoma, Human Immunodeficiency Virus Infection and other specialties. University of Alabama at Birmingham is involved with conducting 2,622 clinical trials across 1,825 conditions. There are 275 research doctors associated with this hospital, such as Mustafa Ahmed, MD, Girish Dhall, MD, Pankit Vachhani, and Waldemar A Carlo, MD.Area of expertise
1Fibrosis
Global LeaderCFTR
3849+10Kb C->T positive
621+1G->T
2Breast Cancer
Global LeaderStage IV
Stage III
HER2 negative
Top PIs
Mustafa Ahmed, MDUniversity of Alabama at Birmingham6 years of reported clinical research
Studies Mitral Valve Regurgitation
Studies Heart Failure
19 reported clinical trials
32 drugs studied
Girish Dhall, MDChildren's Hospital of Alabama2 years of reported clinical research
Studies Brain Tumor
Studies Recurrence
17 reported clinical trials
36 drugs studied
Pankit VachhaniUniversity of Alabama at Birmingham2 years of reported clinical research
Studies Leukemia
Studies Acute Myeloid Leukemia
15 reported clinical trials
23 drugs studied
Waldemar A Carlo, MDUniversity of Alabama at Birmingham5 years of reported clinical research
Studies Premature Infants
Studies Premature Birth
15 reported clinical trials
21 drugs studied
Clinical Trials running at University of Alabama at Birmingham
Heart Failure
B-Cell Lymphoma
Chronic Obstructive Pulmonary Disease
Stroke
Urinary Incontinence
Lymphoma
Non-Hodgkin's Lymphoma
Atopic Dermatitis
Sickle Cell Anemia
Sickle Cell Disease
Spironolactone
for Heart Failure
Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is a unique Registry-Randomized Clinical Trial (RRCT) that will test the hypothesis that spironolactone plus standard of care compared to standard of care alone reduces the composite of CV mortality and HF hospitalization as follows: Population: HFPEF patients in the Swedish Heart Failure Registry and HFPEF patients in US. HFPEF defined as symptoms/signs of HF, elevated NTproBNP (B-type Natriuretic Peptide; N-terminal pro b-type Natriuretic Peptide) and EF\>=40%. Intervention and control: Randomized 1:1 to intervention: spironolactone + usual care vs. control: usual care alone. Outcome: Primary outcome cardiovascular death or time to HF hospitalization. Secondary outcomes include hospitalization for various causes, adverse events and treatment adherence. In Sweden outcomes are obtained automatically by linking with the Population, Patient and Drug Dispensed Registries. In the US, outcomes will be reported by sites and supplemented by data from a call center. The trial is event-driven with enrollment 7 years and study duration 9 years. For the primary outcome (CV Death or first HF hospitalization) with an event target of 721 events the sample size requires 1985 patients conservatively rounded to approximately 2000 patients.
Recruiting3 awards Phase 37 criteria
Palliative Care
for Advanced Heart Failure
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this randomized factorial pilot trial is to identify feasibility, acceptability, and preliminary efficacy of components of an intervention (UPHOLDS) to improve quality of life of older adults with advanced heart failure. Using a 2x2x2x2 factorial design, 64 adults with advanced heart failure will be randomized to receive one or more palliative care coach-delivered components, based on Ferrans' Health-Related Quality of Life Model: 1) psychoeducation on palliative care principles (4 vs. 8 sessions); 2) financial coaching (yes vs. no); 3) one-time specialty outpatient palliative care consultation (yes vs. no); and monthly follow (1 monthly follow-up call vs. monthly follow-up calls for 24 weeks).
Recruiting1 award N/A2 criteria
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Frequently asked questions
What kind of research happens at University of Alabama at Birmingham?
University of Alabama at Birmingham is a medical facility located in Birmingham, Alabama. This center is recognized for care of Fibrosis, Breast Cancer, Cancer, Lymphoma, Human Immunodeficiency Virus Infection and other specialties. University of Alabama at Birmingham is involved with conducting 2,622 clinical trials across 1,825 conditions. There are 275 research doctors associated with this hospital, such as Mustafa Ahmed, MD, Girish Dhall, MD, Pankit Vachhani, and Waldemar A Carlo, MD.
Where is University of Alabama at Birmingham located?
To reach the University of Alabama at Birmingham (UAB) Hospital:
- Take exit 259B for 4th Ave South and park in the North Pavilion parking deck at the corner of 4th Ave. South and 18th St. South.
- Follow the signs to the West Pavilion using the elevators and crosswalks, and locate the Guest Elevator A–2 Russell Clinic.
- For real-time traffic updates, consider using Waze driving directions.
Who should I call to ask about financial aid or insurance network?
**University of Alabama at Birmingham (UAB) Hospital Financial Assistance:**
- For financial assistance, contact the Financial Assistance department at (205) 801-9910 or toll-free at (800) 388-7210. They offer discounts and payment plans based on the U.S. Government’s Federal Poverty Guidelines.
- To apply, download and complete the application from their website, then return it to the specified address. UAB will notify you of their decision within 7 business days.
**Insurance-Related Inquiries:**
- For insurance questions, reach out to the Office of Student Financial Aid at (205) 934-8223 or via email. Assistance is available Monday to Friday, 8:00 am to 5:00 pm.
- In-person meetings with a Financial Aid Specialist are available at the One Stop Student Services Office in the Hill Student Center during office hours.
What insurance does University of Alabama at Birmingham accept?
The University of Alabama at Birmingham (UAB) accepts most forms of insurance, including Medicare and Medicaid, for medical services at UAB Hospital, UAB Hospital-Highlands, University Emergency Department, and The Kirklin Clinic of UAB Hospital. UAB has contracts with most major insurance companies; however, out-of-state Medicaid is not accepted. Patients are encouraged to bring proper insurance identification cards for claim submission and can receive assistance with forms if they need to file claims personally.
What awards or recognition has University of Alabama at Birmingham received?
The University of Alabama at Birmingham (UAB) Hospital is celebrated for its exceptional workplace environment, earning accolades in Shared Governance, Diversity, Inclusion and Belonging, Confidence in Senior Leadership, and Faculty Experience from the Great Colleges to Work For® program. UAB Medicine stands as the premier hospital in Alabama, recognized by U.S. News & World Report as a leading institution both in the Southeast and nationally, boasting eight nationally-ranked medical programs.