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University of Florida Shands Cancer Center
Claim this profileGainesville, Florida 32608
Global Leader in Leukemia
Global Leader in Lymphoma
Conducts research for Nervous System Tumors
Conducts research for Brain Tumor
Conducts research for Lung Cancer
150 reported clinical trials
7 medical researchers
Summary
University of Florida Shands Cancer Center is a medical facility located in Gainesville, Florida. This center is recognized for care of Leukemia, Lymphoma, Nervous System Tumors, Brain Tumor, Lung Cancer and other specialties. University of Florida Shands Cancer Center is involved with conducting 150 clinical trials across 159 conditions. There are 7 research doctors associated with this hospital, such as Thomas J. George, Thomas Beaver, MD, William Miles, MD, and Erin Dean, MD.Area of expertise
1Leukemia
Global LeaderFLT3 positive
2Lymphoma
Global Leaderlow tumor burden
Stage IV
Stage III
Top PIs
Thomas J. GeorgeUniversity of Florida Health Science Center - Gainesville6 years of reported clinical research
Expert in Cancer
Expert in Tumors
31 reported clinical trials
101 drugs studied
Thomas Beaver, MDUniversity of Florida2 years of reported clinical research
Studies Aortic Valve Stenosis
Studies Aortic Valve Disease
7 reported clinical trials
11 drugs studied
William Miles, MDShands at the University of Florida4 years of reported clinical research
Studies Atrial Fibrillation
Studies Heart Failure
2 reported clinical trials
5 drugs studied
Erin Dean, MDUF Health Shands Cancer Hospital3 years of reported clinical research
Studies Lymphoma
Studies Non-Hodgkin's Lymphoma
1 reported clinical trial
2 drugs studied
Clinical Trials running at University of Florida Shands Cancer Center
Squamous Cell Carcinoma
Non-Hodgkin's Lymphoma
Pancreatic Cancer
Lymphoma
Heart Valve Disease
Valvular Heart Disease
Cardiovascular Disease
Mitral Valve Regurgitation
Mitral Regurgitation
Mitral Valve Disease
Tisotumab Vedotin
for Cancer
This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors and what side effects (unwanted effects) may occur. There are seven parts to this study. * In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). * In Part B, participants will receive tisotumab vedotin on Days 1, 8, and 15 every 4-week cycle. * In Part C, participants will receive tisotumab vedotin on Days 1 and 15 of every 4-week cycle. * In Part D, participants will be given treatment on Day 1 of every 3-week cycle. Participants in Part D will get tisotumab vedotin with either: * Pembrolizumab or, * Pembrolizumab and carboplatin, or * Pembrolizumab and cisplatin * In Part E, participants will receive tisotumab vedotin on Days 1 and 15 of every 4-week cycle. * In Part F, participants will receive tisotumab vedotin on Days 1, 15, and 29 of every 6-week cycle. Participants in Part F will get tisotumab vedotin with pembrolizumab. * In Part G, participants will receive tisotumab vedotin on Days 1, 15, and 29 of every 6-week cycle. Participants in Part G will get tisotumab vedotin with pembrolizumab and carboplatin.
Recruiting1 award Phase 216 criteria
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Frequently asked questions
What kind of research happens at University of Florida Shands Cancer Center?
University of Florida Shands Cancer Center is a medical facility located in Gainesville, Florida. This center is recognized for care of Leukemia, Lymphoma, Nervous System Tumors, Brain Tumor, Lung Cancer and other specialties. University of Florida Shands Cancer Center is involved with conducting 150 clinical trials across 159 conditions. There are 7 research doctors associated with this hospital, such as Thomas J. George, Thomas Beaver, MD, William Miles, MD, and Erin Dean, MD.