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UPMC Pinnacle Harrisburg
Claim this profileHarrisburg, Pennsylvania 17101
Global Leader in Breast Cancer
Global Leader in Aortic Valve Stenosis
Conducts research for Lung Cancer
Conducts research for Cancer
Conducts research for Atrial Fibrillation
93 reported clinical trials
16 medical researchers
Summary
UPMC Pinnacle Harrisburg is a medical facility located in Harrisburg, Pennsylvania. This center is recognized for care of Breast Cancer, Aortic Valve Stenosis, Lung Cancer, Cancer, Atrial Fibrillation and other specialties. UPMC Pinnacle Harrisburg is involved with conducting 93 clinical trials across 121 conditions. There are 16 research doctors associated with this hospital, such as Liza C. Villaruz, Adam Brufsky, MD, Dan P. Zandberg, and Hemal Gada, MD.Area of expertise
1Breast Cancer
Global LeaderHER2 negative
Stage IV
ER positive
2Aortic Valve Stenosis
Global LeaderTop PIs
Liza C. VillaruzUniversity of Pittsburgh Cancer Institute (UPCI)5 years of reported clinical research
Expert in Lung Cancer
Expert in Non-Small Cell Lung Cancer
37 reported clinical trials
53 drugs studied
Adam Brufsky, MDUniversity of Pittsburgh Cancer Institute (UPCI)1 year of reported clinical research
Expert in Breast Cancer
Studies Cancer
31 reported clinical trials
70 drugs studied
Dan P. ZandbergUniversity of Pittsburgh Cancer Institute (UPCI)1 year of reported clinical research
Expert in Cancer
Expert in Squamous Cell Carcinoma
18 reported clinical trials
33 drugs studied
Hemal Gada, MDUPMC Pinnacle Harrisburg Campus5 years of reported clinical research
Studies Aortic Valve Stenosis
Studies Mitral Valve Regurgitation
19 reported clinical trials
26 drugs studied
Clinical Trials running at UPMC Pinnacle Harrisburg
Breast Cancer
Non-Small Cell Lung Cancer
Lung Cancer
Mitral Valve Regurgitation
Aortic Valve Stenosis
Heart Failure
Stroke
ALK Gene Rearrangement
Tricuspid Regurgitation
Cancer
Giredestrant + Hormone Therapy
for Early-Stage Breast Cancer
This trial is testing giredestrant, a medication given after initial treatment to prevent breast cancer from returning. It focuses on patients with a specific type of early-stage breast cancer that is hormone-driven and at higher risk of recurrence. Giredestrant works by blocking the hormone estrogen from helping cancer cells grow. Giredestrant has shown promise in previous studies.
Recruiting2 awards Phase 311 criteria
Chemotherapy Reduction After Surgery
for Breast Cancer
This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment.
Recruiting1 award Phase 227 criteria
Marker-Directed Monitoring
for Breast Cancer
This trial studies if using blood tests to decide when to do scans is as effective as the standard way for monitoring patients with a specific type of breast cancer that has spread. The blood tests act like an early warning system for cancer activity.
Recruiting1 award N/A
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Frequently asked questions
What kind of research happens at UPMC Pinnacle Harrisburg?
UPMC Pinnacle Harrisburg is a medical facility located in Harrisburg, Pennsylvania. This center is recognized for care of Breast Cancer, Aortic Valve Stenosis, Lung Cancer, Cancer, Atrial Fibrillation and other specialties. UPMC Pinnacle Harrisburg is involved with conducting 93 clinical trials across 121 conditions. There are 16 research doctors associated with this hospital, such as Liza C. Villaruz, Adam Brufsky, MD, Dan P. Zandberg, and Hemal Gada, MD.